Anxiety and Mindfulness in the Relationship Between Stress and Depression in Patients With Coronary Artery Disease: A Parallel Mediation Analysis.
4 affiliations
- 1Kyungpook National University College of Nursing, Daegu, South Korea.
- 2Daegu Health College of Nursing, Daegu, South Korea.
- 3Pohang SeMyung Christianity Hospital, Pohang-si, Gyeongsangbuk-do, South Korea.
- 4Daegu Catholic University College of Nursing, Daegu, South Korea.
Abstract
Aim
To examine the indirect effect of anxiety and mindfulness on the relationship between stress and depression in patients with coronary artery disease.Design
A correlational, cross-sectional design was used.Methods
Participants of this study comprised 112 patients with coronary artery disease recruited from a general hospital in South Korea between January and September 2021. The Korean versions of the Depression Anxiety Stress Scale-21 and Mindful Attention Awareness Scale were used. Data were analysed using parallel multiple mediation analysis (PROCESS macro Model 4).Results
Stress, anxiety, mindfulness and depression were significantly correlated. The total indirect effect through anxiety and mindfulness on the relationship between stress and depression was significant (B = 0.37, 95% CI [0.200, 0.592]). The specific indirect effect through mindfulness was significant (B = 0.26, 95% CI [0.122, 0.423]), whereas the indirect effect through anxiety was not statistically significant (B = 0.11, 95% CI [-0.003, 0.268]).Conclusion
Mindfulness may be an important psychological factor associated with the relationship between stress and depression in patients with coronary artery disease. Further research is needed to clarify the role of anxiety in this relationship.Implications for the profession and patient care
Mindfulness-based approaches may be considered as complementary strategies for managing psychological distress and depressive symptoms in patients with coronary artery disease. Anxiety should also be assessed as part of comprehensive psychological care.
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BibTeX
@article{song2026anxiety,
title = {{Anxiety and Mindfulness in the Relationship Between Stress and Depression in Patients With Coronary Artery Disease: A Parallel Mediation Analysis.}},
author = {Yeoungsuk Song and Yoonmi Lee and Hong A Lim and Junghoon Lee},
journal = {Nursing open},
year = {2026},
month = oct,
doi = {10.1002/nop2.70992},
url = {https://europepmc.org/article/MED/42963779},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Anxiety and Mindfulness in the Relationship Between Stress and Depression in Patients With Coronary Artery Disease: A Parallel Mediation Analysis.
AU - Yeoungsuk Song
AU - Yoonmi Lee
AU - Hong A Lim
AU - Junghoon Lee
PY - 2026
DA - 2026/10/30
JO - Nursing open
DO - 10.1002/nop2.70992
UR - https://europepmc.org/article/MED/42963779
AB - Aim To examine the indirect effect of anxiety and mindfulness on the relationship between stress and depression in patients with coronary artery disease.Design A correlational, cross-sectional design was used.Methods Participants of this study comprised 112 patients with coronary artery disease recruited from a general hospital in South Korea between January and September 2021. The Korean versions of the Depression Anxiety Stress Scale-21 and Mindful Attention Awareness Scale were used. Data were analysed using parallel multiple mediation analysis (PROCESS macro Model 4).Results Stress, anxiety, mindfulness and depression were significantly correlated. The total indirect effect through anxiety and mindfulness on the relationship between stress and depression was significant (B = 0.37, 95% CI [0.200, 0.592]). The specific indirect effect through mindfulness was significant (B = 0.26, 95% CI [0.122, 0.423]), whereas the indirect effect through anxiety was not statistically significant (B = 0.11, 95% CI [-0.003, 0.268]).Conclusion Mindfulness may be an important psychological factor associated with the relationship between stress and depression in patients with coronary artery disease. Further research is needed to clarify the role of anxiety in this relationship.Implications for the profession and patient care Mindfulness-based approaches may be considered as complementary strategies for managing psychological distress and depressive symptoms in patients with coronary artery disease. Anxiety should also be assessed as part of comprehensive psychological care.
SN - 2054-1058
ER -