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Peer-reviewedCC BYFrontiers in public health

eHealth literacy and decisional conflict in patients with coronary heart disease: chain mediation of cyberchondria and psychological inflexibility and a latent profile analysis

6 affiliations
  1. 1Clinical Pharmacy Center, Nanfang Hospital, Southern Medical University , , ,
  2. 2Department of Medical Imaging Function, Xi'an Electric Power Central Hospital , , ,
  3. 3Operating Department, Zhumadian Central Hospital , , ,
  4. 4Department of Emergency, Nanfang Hospital, Southern Medical University , , ,
  5. 5Department of Emergency, Ganzhou People's Hospital , , ,
  6. 6Department of Cardiology, Nanfang Hospital, Southern Medical University , , ,

Abstract

Background: Coronary heart disease (CHD) is the leading cause of cardiovascular mortality worldwide, and its management requires patients to make complex, preference-sensitive treatment decisions. Decisional conflict is common in this population and adversely affects treatment adherence and outcomes, yet its association with eHealth literacy and the underlying psychological mechanisms remain unclear.

Objective: This study examined the association between eHealth literacy and decisional conflict in patients with CHD, tested the chain-mediating roles of cyberchondria and psychological inflexibility, and identified latent profiles of eHealth literacy.

Methods: A cross-sectional design was employed, and patients with CHD were recruited from tertiary Grade A hospitals. The survey battery comprised the eHealth Literacy Scale, the Decisional Conflict Scale, the Cyberchondria Severity Scale, the psychological inflexibility subscale of the Multidimensional Psychological Flexibility Inventory, and requisite demographic items.

Results: eHealth literacy was significantly and negatively associated with decisional conflict, and this association was mediated by cyberchondria and psychological inflexibility. From a person-centered perspective, two latent subgroups of eHealth literacy were identified: a high eHealth literacy profile and a low eHealth literacy profile. One-way analysis of variance indicated that the optimal latent profiles differed significantly in decisional conflict, cyberchondria, and psychological inflexibility.

Conclusion: This study not only helps identify priority targets for interventions addressing decisional conflict in patients with CHD, but also elucidates the psychological pathways through which eHealth literacy shapes treatment decision-making, thereby informing heterogeneity-informed, tailored clinical interventions.

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BibTeX
@article{huang2026ehealth,
  title = {{eHealth literacy and decisional conflict in patients with coronary heart disease: chain mediation of cyberchondria and psychological inflexibility and a latent profile analysis}},
  author = {Yan Huang and Tianyu She and Pei Gao and Ping Zhang and Yuhan Cai and Guihua Zeng and Donglian Liu and Zhao Tang and Gang Wen},
  journal = {Frontiers in public health},
  year = {2026},
  month = oct,
  doi = {10.3389/fpubh.2026.1964166},
  url = {https://europepmc.org/article/PMC/PMC13669096},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - eHealth literacy and decisional conflict in patients with coronary heart disease: chain mediation of cyberchondria and psychological inflexibility and a latent profile analysis
AU  - Yan Huang
AU  - Tianyu She
AU  - Pei Gao
AU  - Ping Zhang
AU  - Yuhan Cai
AU  - Guihua Zeng
AU  - Donglian Liu
AU  - Zhao Tang
AU  - Gang Wen
PY  - 2026
DA  - 2026/10/01
JO  - Frontiers in public health
DO  - 10.3389/fpubh.2026.1964166
UR  - https://europepmc.org/article/PMC/PMC13669096
AB  - Background: Coronary heart disease (CHD) is the leading cause of cardiovascular mortality worldwide, and its management requires patients to make complex, preference-sensitive treatment decisions. Decisional conflict is common in this population and adversely affects treatment adherence and outcomes, yet its association with eHealth literacy and the underlying psychological mechanisms remain unclear.  Objective: This study examined the association between eHealth literacy and decisional conflict in patients with CHD, tested the chain-mediating roles of cyberchondria and psychological inflexibility, and identified latent profiles of eHealth literacy.  Methods: A cross-sectional design was employed, and patients with CHD were recruited from tertiary Grade A hospitals. The survey battery comprised the eHealth Literacy Scale, the Decisional Conflict Scale, the Cyberchondria Severity Scale, the psychological inflexibility subscale of the Multidimensional Psychological Flexibility Inventory, and requisite demographic items.  Results: eHealth literacy was significantly and negatively associated with decisional conflict, and this association was mediated by cyberchondria and psychological inflexibility. From a person-centered perspective, two latent subgroups of eHealth literacy were identified: a high eHealth literacy profile and a low eHealth literacy profile. One-way analysis of variance indicated that the optimal latent profiles differed significantly in decisional conflict, cyberchondria, and psychological inflexibility.  Conclusion: This study not only helps identify priority targets for interventions addressing decisional conflict in patients with CHD, but also elucidates the psychological pathways through which eHealth literacy shapes treatment decision-making, thereby informing heterogeneity-informed, tailored clinical interventions.
SN  - 2296-2565
ER  -