Efficacy, Buffering Capacity and Dynamics of Saliva-Stimulating Products.
5 affiliations
- 1Heba Ashi Associate Professor, Department of Dental Public Health, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia. Experimental design, performed the experiments, wrote the manuscript.
- 2Guglielmo Campus Senior Lecturer, Department of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Box 450, SE-405 30 Gothenburg, Sweden; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy. Idea contribution, performed the statistical evaluation, wrote the manuscript and contributed substantially to the discussion.
- 3Anna Lehrkinder Biomedical Scientist, Department of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Box 450, SE-405 30 Gothenburg, Sweden. Experimental design, performed the experiments, proofread the manuscript, performed a certain test, contributed substantially to the discussion.
- 4Ali Alshabeeb Biomedical Scientist, Department of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Box 450, SE-405 30 Gothenburg, Sweden. Performed the experiments, performed a certain test, and proofread the manuscript.
- 5Peter Lingström Professor, Department of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Box 450, SE-405 30 Gothenburg, Sweden. Idea, hypothesis, experimental design, wrote the manuscript, proofread the manuscript and contributed substantially to the discussion.
Abstract
Background
Saliva maintains the health and integrity of the oral cavity while composing a complex symphony within it. Saliva's lubricating qualities not only make talking and swallowing easier, but also promote digestion by breaking down lipids and carbohydrates through enzymatic processes.Aim
To compare the efficacy, buffering capacity and temporal dynamics of six different saliva-stimulating products in a randomised controlled crossover trial.Methods and materials
Twelve healthy adults were enrolled, each testing six products (chewing gum with mint, Salivin, Jaw Peer medium, Jaw Peer large, Jaw Peer small and control) on separate days. Stimulated saliva secretion rate, buffering capacity, and pH were measured at baseline and at 1, 3 and 6 min following product use. Comparison between products and different time points for the same product was performed using two-way ANOVA followed by Tukey's post hoc test. A significance level of p 0.05 was applied for statistical significance.Results
Chewing gum with mint and Jaw Peer large produced the highest stimulated saliva secretion rates. The Jaw Peer product showed the greatest decrease in buffering capacity, while Salivin showed stable buffering capacity over time. Significant temporal variations in buffering capacity were observed for all products. No significant differences were found in unstimulated salivary secretion rate between products.Conclusions
Unstimulated salivary flow rate products exhibit different effects on salivary flow, buffering capacity, and temporal dynamics. Choice of product should be individualised based on patient preferences, specific clinical needs and duration of action, although very limited improvement was noticed with these saliva-stimulating products compared to chewing paraffin alone.
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BibTeX
@article{ashi2026efficacy,
title = {{Efficacy, Buffering Capacity and Dynamics of Saliva-Stimulating Products.}},
author = {Heba Ashi and Guglielmo Campus and Anna Lehrkinder and Ali Alshabeeb and Peter Lingström},
journal = {Oral health \& preventive dentistry},
year = {2026},
month = oct,
doi = {10.3290/j.ohpd.c_2850},
url = {https://europepmc.org/article/MED/42905046},
note = {CC BY},
}
RIS
TY - JOUR
TI - Efficacy, Buffering Capacity and Dynamics of Saliva-Stimulating Products.
AU - Heba Ashi
AU - Guglielmo Campus
AU - Anna Lehrkinder
AU - Ali Alshabeeb
AU - Peter Lingström
PY - 2026
DA - 2026/10/21
JO - Oral health & preventive dentistry
DO - 10.3290/j.ohpd.c_2850
UR - https://europepmc.org/article/MED/42905046
AB - Background Saliva maintains the health and integrity of the oral cavity while composing a complex symphony within it. Saliva's lubricating qualities not only make talking and swallowing easier, but also promote digestion by breaking down lipids and carbohydrates through enzymatic processes.Aim To compare the efficacy, buffering capacity and temporal dynamics of six different saliva-stimulating products in a randomised controlled crossover trial.Methods and materials Twelve healthy adults were enrolled, each testing six products (chewing gum with mint, Salivin, Jaw Peer medium, Jaw Peer large, Jaw Peer small and control) on separate days. Stimulated saliva secretion rate, buffering capacity, and pH were measured at baseline and at 1, 3 and 6 min following product use. Comparison between products and different time points for the same product was performed using two-way ANOVA followed by Tukey's post hoc test. A significance level of p 0.05 was applied for statistical significance.Results Chewing gum with mint and Jaw Peer large produced the highest stimulated saliva secretion rates. The Jaw Peer product showed the greatest decrease in buffering capacity, while Salivin showed stable buffering capacity over time. Significant temporal variations in buffering capacity were observed for all products. No significant differences were found in unstimulated salivary secretion rate between products.Conclusions Unstimulated salivary flow rate products exhibit different effects on salivary flow, buffering capacity, and temporal dynamics. Choice of product should be individualised based on patient preferences, specific clinical needs and duration of action, although very limited improvement was noticed with these saliva-stimulating products compared to chewing paraffin alone.
SN - 1602-1622
SN - 1757-9996
ER -