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Peer-reviewedCC BYFrontiers in immunology

The cross-talk between T and B lymphocytes and the oral microbiome in health and disease: a narrative review

  • Iwona Ordyniec-Kwaśnica1
  • Bartosz Słomiński2
  • Mateusz Lampkowski1
  • Anna Kudra3
  • Damian Muszyński4
4 affiliations
  1. 1Division of Dental Prosthetics, Medical University of Gdańsk , ,
  2. 2Department of Medical Immunology, Medical University of Gdańsk , ,
  3. 3”Zdrowie“ LLC DENTUS Dental Clinics in Gdynia , ,
  4. 4Pomeranian Dental Center Kryspin-Dent , ,
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Abstract

T and B lymphocytes are key components of the adaptive immune system, playing a central role in maintaining host homeostasis and protecting against a wide range of pathogens. A comparable form of homeostatic regulation can be observed in microbial ecosystems, including the oral cavity. This environment is extremely unstable and can be easily disrupted by various factors or stimuli. This review article presents the different types of T and B lymphocytes and their role in the human body, and attempts to answer the question of how these two basic types of immune system cells can affect the imbalance of the oral microbiome.

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Cite

BibTeXRIS
BibTeX
@article{ordynieckwasnica2026crosstalk,
  title = {{The cross-talk between T and B lymphocytes and the oral microbiome in health and disease: a narrative review}},
  author = {Iwona Ordyniec-Kwaśnica and Bartosz Słomiński and Mateusz Lampkowski and Anna Kudra and Damian Muszyński},
  journal = {Frontiers in immunology},
  year = {2026},
  month = sep,
  doi = {10.3389/fimmu.2026.1862609},
  url = {https://europepmc.org/article/PMC/PMC13662638},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - The cross-talk between T and B lymphocytes and the oral microbiome in health and disease: a narrative review
AU  - Iwona Ordyniec-Kwaśnica
AU  - Bartosz Słomiński
AU  - Mateusz Lampkowski
AU  - Anna Kudra
AU  - Damian Muszyński
PY  - 2026
DA  - 2026/09/30
JO  - Frontiers in immunology
DO  - 10.3389/fimmu.2026.1862609
UR  - https://europepmc.org/article/PMC/PMC13662638
AB  - T and B lymphocytes are key components of the adaptive immune system, playing a central role in maintaining host homeostasis and protecting against a wide range of pathogens. A comparable form of homeostatic regulation can be observed in microbial ecosystems, including the oral cavity. This environment is extremely unstable and can be easily disrupted by various factors or stimuli. This review article presents the different types of T and B lymphocytes and their role in the human body, and attempts to answer the question of how these two basic types of immune system cells can affect the imbalance of the oral microbiome.
SN  - 1664-3224
ER  -