Skip to content
DraconiticResearch
Search Sources API
181,713 studies31 sourcesUpdated 15 min ago
Peer-reviewedLicence not statedCell

A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death

  • Meredith Nicole Nix1,2
  • Sai P. Gourisankar3,2
  • Kevin Bowman4,2
  • Sabin A. Nettles5,2
  • H H Yang4,2
  • Brendan G. Dwyer3,2
  • Roman C. Sarott3,2
  • Hind Z. Abuzaid5,6
  • Michael M. Martinez3,2
  • Nick A. Phillips7,2
  • Vincent Cabaud Gibouin4,2
  • Artur Hakobyan8,2
19 more authors
  • Vahram Arakelov8,2
  • Garik Petrosyan8,2
  • Aram Davtyan8,2
  • Yanlan Wang5,2
  • Juste Simanauskaite5,2
  • Bryan A. Romero3,2
  • Hannah M. Jones3,2
  • A. Krokhotin5,6
  • Tara N. Lowensohn9,2
  • Lei Chen10,2
  • Cara Low3,2
  • Hannes S. Vogel5
  • Mark M. Davis10
  • Daniel Fernández11
  • Tinghu Zhang3
  • Michael R. Green12
  • Stephen M. Hinshaw13
  • Nathanael S. Gray14
  • Gerald R. Crabtree15
15 affiliations
  1. 1Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA; Department of Chemistry, Stanford University, Stanford, CA, USA
  2. 2Stanford University
  3. 3Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA
  4. 4Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA
  5. 5Department of Pathology, Stanford University, Stanford, CA, USA
  6. 6University of Texas MD Anderson Cancer Center
  7. 7Department of Cancer Biology, Stanford University, Stanford, CA, USA
  8. 8Deep Origin, South San Francisco, CA, USA
  9. 9Department of Chemistry, Stanford University, Stanford, CA, USA
  10. 10Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA
  11. 11Macromolecular Structure, Nucleus at Sarafan ChEM-H, Stanford University, Stanford, CA, USA
  12. 12Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: [email protected]
  13. 13Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA. Electronic address: [email protected]
  14. 14Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA. Electronic address: [email protected]
  15. 15Department of Pathology, Stanford University, Stanford, CA, USA; Department of Developmental Biology, Stanford University, Stanford, CA, USA. Electronic address: [email protected]
Open at sourceDOICite

Related

  1. Sphingolipid metabolic subtyping defines SPHK1 as an oncogene and characterizes immunosuppressive TME features in gastric cancer.
    Zeyu Wang, Zhuying Yue, Chengkai Jiang
    Cancer cell internationalPeer-reviewedCC BYFull textMolecular biology & gene regulationEurope PMCDOAJ
  2. Scaling of structural variability of ecDNA polymer condensates with copy number boosts and stabilises oncogene regulatory contacts
    M. Conte, S. Kundu, S. Guha +1
    bioRxivPreprintCC BY-NC-NDFull textBiophysicsbioRxiv
  3. A tight inducible model for oncogene function and drug testing
    Matthias Hamdorf, Luca Wallner, Sonja Sternberg +2
    Scientific ReportsPeer-reviewedCC BY 4.0Full textMolecular biology & gene regulationCrossrefDOAJ
  4. Self-assembled nucleolipid G-quadruplexes act as multitarget decoys for oncogene suppression in pancreatic cancer
    Faith Kivunga, Virginie Baylot, Tina Kauss +6
    Scientific ReportsPeer-reviewedCC BY 4.0Full textMolecular biology & gene regulationCrossref
  5. Avidity by Design: Scalable Programmed Synthesis of Bivalent DNA-Encoded Libraries for Enhanced Selection Sensitivity
    Spurti U Akki, Yasmin Arjomandi, Tracy Chan +13
    ChemRxivPreprintCC BY-NC-NDFull textMolecular biology & gene regulationChemRxiv

Cite

BibTeXRIS
BibTeX
@article{nix2026bivalent,
  title = {{A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death}},
  author = {Meredith Nicole Nix and Sai P. Gourisankar and Kevin Bowman and Sabin A. Nettles and H H Yang and Brendan G. Dwyer and Roman C. Sarott and Hind Z. Abuzaid and Michael M. Martinez and Nick A. Phillips and Vincent Cabaud Gibouin and Artur Hakobyan and Vahram Arakelov and Garik Petrosyan and Aram Davtyan and Yanlan Wang and Juste Simanauskaite and Bryan A. Romero and Hannah M. Jones and A. Krokhotin and Tara N. Lowensohn and Lei Chen and Cara Low and Hannes S. Vogel and Mark M. Davis and Daniel Fernández and Tinghu Zhang and Michael R. Green and Stephen M. Hinshaw and Nathanael S. Gray and Gerald R. Crabtree},
  journal = {Cell},
  year = {2026},
  month = jul,
  doi = {10.1016/j.cell.2026.06.037},
  url = {https://doi.org/10.1101/2025.03.14.643404},
}
RIS
TY  - JOUR
TI  - A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death
AU  - Meredith Nicole Nix
AU  - Sai P. Gourisankar
AU  - Kevin Bowman
AU  - Sabin A. Nettles
AU  - H H Yang
AU  - Brendan G. Dwyer
AU  - Roman C. Sarott
AU  - Hind Z. Abuzaid
AU  - Michael M. Martinez
AU  - Nick A. Phillips
AU  - Vincent Cabaud Gibouin
AU  - Artur Hakobyan
AU  - Vahram Arakelov
AU  - Garik Petrosyan
AU  - Aram Davtyan
AU  - Yanlan Wang
AU  - Juste Simanauskaite
AU  - Bryan A. Romero
AU  - Hannah M. Jones
AU  - A. Krokhotin
AU  - Tara N. Lowensohn
AU  - Lei Chen
AU  - Cara Low
AU  - Hannes S. Vogel
AU  - Mark M. Davis
AU  - Daniel Fernández
AU  - Tinghu Zhang
AU  - Michael R. Green
AU  - Stephen M. Hinshaw
AU  - Nathanael S. Gray
AU  - Gerald R. Crabtree
PY  - 2026
DA  - 2026/07/20
JO  - Cell
DO  - 10.1016/j.cell.2026.06.037
UR  - https://doi.org/10.1101/2025.03.14.643404
SN  - 0092-8674
SN  - 1097-4172
ER  -