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Peer-reviewedCC BY 4.0Frontiers in Radiology

Evaluating the impact of passive driver position on image consistency and repeatability in 3.0T cardiac magnetic resonance elastography

  • Jun Wang1,2,3
  • Shutian An1,2,3
  • Zhen Wang1,2,3
  • Zichen Hu1,2,3
  • Yueyue Zhang1,2,3
  • Daiwang Jia1,2,3
  • Yong Cheng1,2,3
  • Yang Xiang1,2,3
  • Ruan Fang1,2,3
  • Peiyang Zheng4
  • Zijun Zheng1,2,3
  • Zhanglei Li1,2,3
4 more authors
  • Yewen Jiang1,2,3
  • Yongqiang Yu1,2,3
  • Ren Zhao4
  • Xiaohu Li1,2,3
4 affiliations
  1. 1Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
  2. 2Research Center of Clinical Medical Imaging, Hefei, Anhui, China
  3. 3Anhui Province Clinical Image Quality Control Center, Hefei, Anhui, China
  4. 4Department of Cardiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
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Abstract

Background: Cardiac magnetic resonance elastography (MRE) is a non-invasive technique that quantifies myocardial stiffness by tracking shear wave propagation through the heart. Shear waves are generated externally and delivered to the thorax through a passive driver placed on the chest. Passive driver position is a critical yet underexplored determinant of measurement quality.

Purpose: To compare two passive driver positions in 3.0 T cardiac MRE — the apical surface projection (ASP) and the left lateral chest wall (LCW) — and to determine which yields more reliable left ventricular (LV) myocardial stiffness measurements.

Methods: Twenty-three healthy volunteers (mean age 43.0 ± 17.0 years; 14 men, 9 women) underwent two cardiac MRE acquisitions, with the passive driver placed first at the ASP and then at the LCW. LV myocardial stiffness and the octahedral shear strain signal-to-noise ratio (OSS-SNR) were measured at both positions. Differences between positions were analyzed using paired t-tests with Cohen's d. Inter- and intra-observer reproducibility were assessed using intraclass correlation coefficients (ICC) and Bland–Altman analysis.

Results: Myocardial stiffness was significantly lower at the ASP than at the LCW (9.0 ± 1.7 kPa vs. 14.7 ± 3.0 kPa; mean difference −5.8 kPa, 95% CI −7.2 to −4.3; P<0.001; Cohen's d=−1.73). OSS-SNR was significantly higher at the ASP (1.72 ± 0.48 vs. 1.25 ± 0.29; P<0.001; Cohen's d=0.85). At the ASP, stiffness measurements demonstrated excellent intra- and inter-observer agreement, with ICCs of 0.962 and 0.963, respectively. At the LCW, stiffness measurements demonstrated good inter-observer agreement and excellent intra-observer agreement, with ICCs of 0.839 and 0.914, respectively.

Conclusion: Passive driver placement at the ASP resulted in significantly higher OSS-SNR and superior reproducibility for LV myocardial stiffness measurements compared with LCW placement. Therefore, the ASP should be considered the preferred driver position for cardiac MRE in clinical and research settings.

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Cite

BibTeXRIS
BibTeX
@article{wang2026evaluating,
  title = {{Evaluating the impact of passive driver position on image consistency and repeatability in 3.0T cardiac magnetic resonance elastography}},
  author = {Jun Wang and Shutian An and Zhen Wang and Zichen Hu and Yueyue Zhang and Daiwang Jia and Yong Cheng and Yang Xiang and Ruan Fang and Peiyang Zheng and Zijun Zheng and Zhanglei Li and Yewen Jiang and Yongqiang Yu and Ren Zhao and Xiaohu Li},
  journal = {Frontiers in Radiology},
  year = {2026},
  month = oct,
  doi = {10.3389/fradi.2026.1912855},
  url = {https://doi.org/10.3389/fradi.2026.1912855},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Evaluating the impact of passive driver position on image consistency and repeatability in 3.0T cardiac magnetic resonance elastography
AU  - Jun Wang
AU  - Shutian An
AU  - Zhen Wang
AU  - Zichen Hu
AU  - Yueyue Zhang
AU  - Daiwang Jia
AU  - Yong Cheng
AU  - Yang Xiang
AU  - Ruan Fang
AU  - Peiyang Zheng
AU  - Zijun Zheng
AU  - Zhanglei Li
AU  - Yewen Jiang
AU  - Yongqiang Yu
AU  - Ren Zhao
AU  - Xiaohu Li
PY  - 2026
DA  - 2026/10/12
JO  - Frontiers in Radiology
DO  - 10.3389/fradi.2026.1912855
UR  - https://doi.org/10.3389/fradi.2026.1912855
AB  - Background: Cardiac magnetic resonance elastography (MRE) is a non-invasive technique that quantifies myocardial stiffness by tracking shear wave propagation through the heart. Shear waves are generated externally and delivered to the thorax through a passive driver placed on the chest. Passive driver position is a critical yet underexplored determinant of measurement quality.  Purpose: To compare two passive driver positions in 3.0 T cardiac MRE — the apical surface projection (ASP) and the left lateral chest wall (LCW) — and to determine which yields more reliable left ventricular (LV) myocardial stiffness measurements.  Methods: Twenty-three healthy volunteers (mean age 43.0 ± 17.0 years; 14 men, 9 women) underwent two cardiac MRE acquisitions, with the passive driver placed first at the ASP and then at the LCW. LV myocardial stiffness and the octahedral shear strain signal-to-noise ratio (OSS-SNR) were measured at both positions. Differences between positions were analyzed using paired t-tests with Cohen's d. Inter- and intra-observer reproducibility were assessed using intraclass correlation coefficients (ICC) and Bland–Altman analysis.  Results: Myocardial stiffness was significantly lower at the ASP than at the LCW (9.0 ± 1.7 kPa vs. 14.7 ± 3.0 kPa; mean difference −5.8 kPa, 95% CI −7.2 to −4.3; P<0.001; Cohen's d=−1.73). OSS-SNR was significantly higher at the ASP (1.72 ± 0.48 vs. 1.25 ± 0.29; P<0.001; Cohen's d=0.85). At the ASP, stiffness measurements demonstrated excellent intra- and inter-observer agreement, with ICCs of 0.962 and 0.963, respectively. At the LCW, stiffness measurements demonstrated good inter-observer agreement and excellent intra-observer agreement, with ICCs of 0.839 and 0.914, respectively.  Conclusion: Passive driver placement at the ASP resulted in significantly higher OSS-SNR and superior reproducibility for LV myocardial stiffness measurements compared with LCW placement. Therefore, the ASP should be considered the preferred driver position for cardiac MRE in clinical and research settings.
SN  - 2673-8740
ER  -