Green phytofabrication of silver nanoparticles from underexplored cypriot plant species with tunable antimicrobial, antioxidant and anticancer activities.
5 affiliations
- 1Department of Bioengineering, Faculty of Engineering, Cyprus International University North Cyprus, Via Mersin 10 Haspolat Nicosia Turkey [email protected].
- 2Biotechnology Research Centre, Cyprus International University North Cyprus, Via Mersin 10 Haspolat Nicosia Turkey.
- 3Department of Basic Sciences and Humanities, Faculty of Arts and Sciences, Cyprus International University North Cyprus, Via Mersin 10 Haspolat Nicosia Turkey.
- 4Irfan Suat Gunsel, Operational Research Institute, Near East University TRNC Mersin 10 Nicosia 99138 Turkey.
- 5Jadara Research Center, Jadara University Jordan.
Abstract
The chemical stability and biocompatibility of nanoparticles produced from plant extracts indicate medicinal implications, rendering them suitable candidates for antibacterial and antioxidant applications. This study aimed to synthesize AgNPs using A. andrachne and P. lentiscus leaf extracts and compare their antioxidant, antibacterial, and anticancer activities. This study presented the green synthesis of highly stable silver nanoparticles, measuring around 90.87 nm and 78.26 nm, derived from the extracts of Arbutus andrachne and Pistacia lentiscus, respectively. The surface compositional analysis of the synthesized silver nanoparticles (AgNPs) was conducted using UV-visible spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, zeta potential analysis, energy-dispersive X-ray spectroscopy, and scanning electron microscopy. Gas chromatography-mass spectrometry analysis was conducted to separate and detect the chemical components of the plant extracts. The antimicrobial efficacy of AgNPs was demonstrated against Escherichia coli and Enterococcus faecalis. Both samples showed significant cytotoxicity against a cancer cell line, with cell viability decreasing as AgNP concentration increased, and it was observed that A. andrachne AgNPs exhibited stronger cytotoxic effects than P. lentiscus AgNPs. Overall, the findings demonstrate the potential of A. andrachne and P. lentiscus extracts for the green synthesis of biologically active AgNPs.
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BibTeX
@article{kavaz2026green,
title = {{Green phytofabrication of silver nanoparticles from underexplored cypriot plant species with tunable antimicrobial, antioxidant and anticancer activities.}},
author = {Doga Kavaz and Temitayo Margaret Omoyeni and Buse Taskiranlar and Huzaifa Umar},
journal = {RSC advances},
year = {2026},
month = oct,
doi = {10.1039/d6ra06253a},
url = {https://europepmc.org/article/MED/42909186},
note = {CC BY},
}
RIS
TY - JOUR
TI - Green phytofabrication of silver nanoparticles from underexplored cypriot plant species with tunable antimicrobial, antioxidant and anticancer activities.
AU - Doga Kavaz
AU - Temitayo Margaret Omoyeni
AU - Buse Taskiranlar
AU - Huzaifa Umar
PY - 2026
DA - 2026/10/21
JO - RSC advances
DO - 10.1039/d6ra06253a
UR - https://europepmc.org/article/MED/42909186
AB - The chemical stability and biocompatibility of nanoparticles produced from plant extracts indicate medicinal implications, rendering them suitable candidates for antibacterial and antioxidant applications. This study aimed to synthesize AgNPs using A. andrachne and P. lentiscus leaf extracts and compare their antioxidant, antibacterial, and anticancer activities. This study presented the green synthesis of highly stable silver nanoparticles, measuring around 90.87 nm and 78.26 nm, derived from the extracts of Arbutus andrachne and Pistacia lentiscus, respectively. The surface compositional analysis of the synthesized silver nanoparticles (AgNPs) was conducted using UV-visible spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, zeta potential analysis, energy-dispersive X-ray spectroscopy, and scanning electron microscopy. Gas chromatography-mass spectrometry analysis was conducted to separate and detect the chemical components of the plant extracts. The antimicrobial efficacy of AgNPs was demonstrated against Escherichia coli and Enterococcus faecalis. Both samples showed significant cytotoxicity against a cancer cell line, with cell viability decreasing as AgNP concentration increased, and it was observed that A. andrachne AgNPs exhibited stronger cytotoxic effects than P. lentiscus AgNPs. Overall, the findings demonstrate the potential of A. andrachne and P. lentiscus extracts for the green synthesis of biologically active AgNPs.
SN - 2046-2069
ER -