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Peer-reviewedCC BY-NC-NDInternal Medicine

Follicular Lymphoma Involving the Supraglottic Larynx in a Patient with Recurrent Cutaneous B-cell Lymphoproliferative Lesions: A Case Report

Abstract

We report a rare case of follicular lymphoma involving the supraglottic larynx in an elderly woman with progressive hoarseness and potential airway compromise. Microlaryngoscopic resection was performed before systemic staging. Histopathology showed grade 1-2 follicular lymphoma. Postoperative FDG PET/CT and a bone marrow biopsy revealed no nodal, visceral, or bone marrow involvement at diagnosis. Because the clonal relationship with previous cutaneous B-cell lymphoproliferative lesions could not be assessed, a primary laryngeal origin could not be established. Involved-site radiotherapy was proposed, but declined by the patient. The patient remained free of local recurrence 6 months after surgery.

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BibTeX
@article{asai2026follicular,
  title = {{Follicular Lymphoma Involving the Supraglottic Larynx in a Patient with Recurrent Cutaneous B-cell Lymphoproliferative Lesions: A Case Report}},
  author = {Ryohei Asai and Hiroumi Matsuzaki and Shimon Otake and Tang Xiaoyan and Takeshi Oshima},
  journal = {Internal Medicine},
  year = {2026},
  month = aug,
  doi = {10.2169/internalmedicine.7631-26},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7631-26/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Follicular Lymphoma Involving the Supraglottic Larynx in a Patient with Recurrent Cutaneous B-cell Lymphoproliferative Lesions: A Case Report
AU  - Ryohei Asai
AU  - Hiroumi Matsuzaki
AU  - Shimon Otake
AU  - Tang Xiaoyan
AU  - Takeshi Oshima
PY  - 2026
DA  - 2026/08/19
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.7631-26
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7631-26/_article
AB  - We report a rare case of follicular lymphoma involving the supraglottic larynx in an elderly woman with progressive hoarseness and potential airway compromise. Microlaryngoscopic resection was performed before systemic staging. Histopathology showed grade 1-2 follicular lymphoma. Postoperative FDG PET/CT and a bone marrow biopsy revealed no nodal, visceral, or bone marrow involvement at diagnosis. Because the clonal relationship with previous cutaneous B-cell lymphoproliferative lesions could not be assessed, a primary laryngeal origin could not be established. Involved-site radiotherapy was proposed, but declined by the patient. The patient remained free of local recurrence 6 months after surgery.
SN  - 1349-7235
SN  - 0918-2918
ER  -