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Peer-reviewedCC BY-NC-NDInternal Medicine

Acute Lower Limb Arterial Occlusion Due to Malignant Lymphoma

  • Hana Isokawa
  • Hiroshi Abe
  • Dai Ozaki
  • Hiroyuki Isogai
  • Tetsuro Miyazaki
  • Takashi Tokano
  • Tohru Minamino
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Abstract

A 72-year-old man presented with acute left lower limb weakness and pain. Acute arterial occlusion was diagnosed, and thrombectomy pathology revealed fibrin-associated diffuse large B-cell lymphoma (FA-DLBCL). No primary lesion was detected on positron emission tomography-computed tomography. However, during radiotherapy for hypopharyngeal cancer, he developed pneumonia and died. Autopsy revealed FA-DLBCL within a mural thrombus distal to an aortic stent graft. A pathological evaluation should be considered in acute limb ischemia with atypical thrombi. FA-DLBCL should be recognized as a potential cause when embolism from mural thrombus is suspected.

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Cite

BibTeXRIS
BibTeX
@article{isokawa2026acute,
  title = {{Acute Lower Limb Arterial Occlusion Due to Malignant Lymphoma}},
  author = {Hana Isokawa and Hiroshi Abe and Dai Ozaki and Hiroyuki Isogai and Tetsuro Miyazaki and Takashi Tokano and Tohru Minamino},
  journal = {Internal Medicine},
  year = {2026},
  month = sep,
  doi = {10.2169/internalmedicine.6700-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6700-25/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Acute Lower Limb Arterial Occlusion Due to Malignant Lymphoma
AU  - Hana Isokawa
AU  - Hiroshi Abe
AU  - Dai Ozaki
AU  - Hiroyuki Isogai
AU  - Tetsuro Miyazaki
AU  - Takashi Tokano
AU  - Tohru Minamino
PY  - 2026
DA  - 2026/09/15
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6700-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6700-25/_article
AB  - A 72-year-old man presented with acute left lower limb weakness and pain. Acute arterial occlusion was diagnosed, and thrombectomy pathology revealed fibrin-associated diffuse large B-cell lymphoma (FA-DLBCL). No primary lesion was detected on positron emission tomography-computed tomography. However, during radiotherapy for hypopharyngeal cancer, he developed pneumonia and died. Autopsy revealed FA-DLBCL within a mural thrombus distal to an aortic stent graft. A pathological evaluation should be considered in acute limb ischemia with atypical thrombi. FA-DLBCL should be recognized as a potential cause when embolism from mural thrombus is suspected.
SN  - 1349-7235
SN  - 0918-2918
ER  -