Peripheral Nerve Schwannoma with an Unusual Anatomical Site.
4 affiliations
- 1National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After Academician V.I. Kulakov of the Ministry of Health of Russia, Moscow 117513, Russia.
- 2Department of Pathology and Clinical Pathology, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
- 3Diagnostic Clinical Center №2, Petrovsky National Research Center of Surgery, Moscow 117593, Russia.
- 4N.N. Blokhin National Medical Research Center of Oncology, Moscow 115522, Russia.
Abstract
We present the case of a 40-year-old woman diagnosed with schwannoma at an infrequent localization. The patient complained of multiple painful lesions in the vulvar region and perianal fold, accompanied by intense, constant pain that slightly increased during menstruation. The initial diagnosis was extragenital endometriosis. Histopathological analysis demonstrated a characteristic proliferation of bland spindle cells arranged in short fascicles containing Verocay bodies, as well as a distinctive immunophenotype, supporting the diagnosis of schwannoma. This case underscores the diagnostic difficulty of distinguishing schwannoma from other mesenchymal tumors and non-tumor lesions at this site using imaging alone and emphasizes the need for histopathological confirmation to reach a definitive diagnosis.
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BibTeX
@article{badlaeva2026peripheral,
title = {{Peripheral Nerve Schwannoma with an Unusual Anatomical Site.}},
author = {Alina Badlaeva and Natalia Mezhelumova and Natalia Arzhanukhina and Dmitry Bulanov},
journal = {Reports (MDPI)},
year = {2026},
month = oct,
doi = {10.3390/reports9040332},
url = {https://europepmc.org/article/MED/42924784},
note = {CC BY},
}
RIS
TY - JOUR
TI - Peripheral Nerve Schwannoma with an Unusual Anatomical Site.
AU - Alina Badlaeva
AU - Natalia Mezhelumova
AU - Natalia Arzhanukhina
AU - Dmitry Bulanov
PY - 2026
DA - 2026/10/01
JO - Reports (MDPI)
DO - 10.3390/reports9040332
UR - https://europepmc.org/article/MED/42924784
AB - We present the case of a 40-year-old woman diagnosed with schwannoma at an infrequent localization. The patient complained of multiple painful lesions in the vulvar region and perianal fold, accompanied by intense, constant pain that slightly increased during menstruation. The initial diagnosis was extragenital endometriosis. Histopathological analysis demonstrated a characteristic proliferation of bland spindle cells arranged in short fascicles containing Verocay bodies, as well as a distinctive immunophenotype, supporting the diagnosis of schwannoma. This case underscores the diagnostic difficulty of distinguishing schwannoma from other mesenchymal tumors and non-tumor lesions at this site using imaging alone and emphasizes the need for histopathological confirmation to reach a definitive diagnosis.
SN - 2571-841X
ER -