Clinical predictors of mortality in earthquake victims with crush-related acute kidney injury requiring hemodialysis.
- 1Department of Nephrology, Adana City Training and Research Hospital, Adana-Türkiye.
- 2Department of Nephrology, Adana Baskent University Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye.
Abstract
Background
Major earthquakes frequently cause crush injuries that lead to acute kidney injury (AKI), posing significant challenges for medical teams. Understanding which patients are at the highest risk of mortality can help physicians make better treatment decisions during these disasters. This study examined earthquake victims who developed severe kidney problems requiring dialysis to identify factors that predict survival.Methods
A retrospective cohort study was conducted at a major tertiary hospital. Of the 5,338 earthquake victims treated, 1,416 adults developed AKI, of whom 159 required hemodialysis for crush-related injuries. Demographics, clinical features, laboratory parameters, and outcomes were analyzed during logistic regression to identify independent predictors of mortality.Results
The cohort's mean age was 38.3±14.6 years, with 62.9% male. Mortality was 30.8%. Independent predictors of mortality were septic shock (odds ratio [OR]: 52.148), elevated sodium levels (OR: 1.186), and hypoalbuminemia (OR: 0.877). Prolonged extrication time, systemic infections, and metabolic acidosis were significantly associated with mortality. Demand for hemodialysis peaked in the 1st week, with hyperkalemia and sepsis as major complications.Conclusion
Mortality among earthquake victims with crush-related renal injury depends primarily on overall disease severity rather than renal function alone. Septic shock, blood chemistry imbalances, and prolonged entrapment were the main determinants of survival. Prompt rescue and aggressive treatment of infections and metabolic problems are essential to saving lives in future disasters.
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BibTeX
@article{tanburoglu2026clinical,
title = {{Clinical predictors of mortality in earthquake victims with crush-related acute kidney injury requiring hemodialysis.}},
author = {Derya Başak Tanburoğlu and Engin Onan and Emrah Gunay and Fatma Ulku Adam and Mehmet Horoz},
journal = {Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma \& emergency surgery : TJTES},
year = {2026},
month = oct,
doi = {10.14744/tjtes.2026.09619},
url = {https://europepmc.org/article/MED/42841886},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Clinical predictors of mortality in earthquake victims with crush-related acute kidney injury requiring hemodialysis.
AU - Derya Başak Tanburoğlu
AU - Engin Onan
AU - Emrah Gunay
AU - Fatma Ulku Adam
AU - Mehmet Horoz
PY - 2026
DA - 2026/10/01
JO - Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
DO - 10.14744/tjtes.2026.09619
UR - https://europepmc.org/article/MED/42841886
AB - Background Major earthquakes frequently cause crush injuries that lead to acute kidney injury (AKI), posing significant challenges for medical teams. Understanding which patients are at the highest risk of mortality can help physicians make better treatment decisions during these disasters. This study examined earthquake victims who developed severe kidney problems requiring dialysis to identify factors that predict survival.Methods A retrospective cohort study was conducted at a major tertiary hospital. Of the 5,338 earthquake victims treated, 1,416 adults developed AKI, of whom 159 required hemodialysis for crush-related injuries. Demographics, clinical features, laboratory parameters, and outcomes were analyzed during logistic regression to identify independent predictors of mortality.Results The cohort's mean age was 38.3±14.6 years, with 62.9% male. Mortality was 30.8%. Independent predictors of mortality were septic shock (odds ratio [OR]: 52.148), elevated sodium levels (OR: 1.186), and hypoalbuminemia (OR: 0.877). Prolonged extrication time, systemic infections, and metabolic acidosis were significantly associated with mortality. Demand for hemodialysis peaked in the 1st week, with hyperkalemia and sepsis as major complications.Conclusion Mortality among earthquake victims with crush-related renal injury depends primarily on overall disease severity rather than renal function alone. Septic shock, blood chemistry imbalances, and prolonged entrapment were the main determinants of survival. Prompt rescue and aggressive treatment of infections and metabolic problems are essential to saving lives in future disasters.
SN - 1306-696X
SN - 1307-7945
ER -