Effects of Vitamin B12 on the Reductive Transformation of PFOS and F-53B by Nanoscale Zero-Valent Zinc.
- 1Ministry of Education Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China.
Abstract
Perfluorooctane sulfonate (PFOS) and 6:2 chlorinated polyfluoroalkyl ether sulfonate (F-53B) are persistent per- and polyfluoroalkyl substances of concern in aquatic environments. This study compared their anaerobic reductive transformation by nanoscale zero-valent zinc (nZn⁰), with and without vitamin B12 (VB12). Solutions containing 1 mg/L PFOS or F-53B were treated with nZn⁰ (278 mg/L) and, where indicated, 0.05 mmol/L VB12 (67.8 mg/L) at pH 8.5 and 30 °C for 20 days. After correction for losses observed in reagent-free blanks, PFOS loss was negligible with nZn⁰ alone but reached approximately 34% with nZn⁰ + VB12, and the corresponding defluorination rate was 33.9%. In contrast, F-53B showed approximately 85% blank-corrected loss by day 6 with either nZn⁰ alone or nZn⁰ + VB12, while defluorination rates reached 38.0% and 30.7%, respectively, indicating no enhancing benefit of VB12 for F-53B under the studied conditions. Nominal-mass LC-MS/MS features consistent with partially defluorinated and hydrogen-substituted products were observed, and tentative transformation pathways were proposed. These results demonstrated compound-specific effects of VB12 and emphasized the distinction among loss, transformation and defluorination when evaluating PFAS destruction.
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BibTeX
@article{gao2026effects,
title = {{Effects of Vitamin B12 on the Reductive Transformation of PFOS and F-53B by Nanoscale Zero-Valent Zinc.}},
author = {Shunshun Gao and Tao Wang and Yun Yang and Qingzhi Cai and Xiaoxia Lu},
journal = {Toxics},
year = {2026},
month = sep,
doi = {10.3390/toxics14100844},
url = {https://europepmc.org/article/MED/42931631},
note = {CC BY},
}
RIS
TY - JOUR
TI - Effects of Vitamin B12 on the Reductive Transformation of PFOS and F-53B by Nanoscale Zero-Valent Zinc.
AU - Shunshun Gao
AU - Tao Wang
AU - Yun Yang
AU - Qingzhi Cai
AU - Xiaoxia Lu
PY - 2026
DA - 2026/09/23
JO - Toxics
DO - 10.3390/toxics14100844
UR - https://europepmc.org/article/MED/42931631
AB - Perfluorooctane sulfonate (PFOS) and 6:2 chlorinated polyfluoroalkyl ether sulfonate (F-53B) are persistent per- and polyfluoroalkyl substances of concern in aquatic environments. This study compared their anaerobic reductive transformation by nanoscale zero-valent zinc (nZn⁰), with and without vitamin B12 (VB12). Solutions containing 1 mg/L PFOS or F-53B were treated with nZn⁰ (278 mg/L) and, where indicated, 0.05 mmol/L VB12 (67.8 mg/L) at pH 8.5 and 30 °C for 20 days. After correction for losses observed in reagent-free blanks, PFOS loss was negligible with nZn⁰ alone but reached approximately 34% with nZn⁰ + VB12, and the corresponding defluorination rate was 33.9%. In contrast, F-53B showed approximately 85% blank-corrected loss by day 6 with either nZn⁰ alone or nZn⁰ + VB12, while defluorination rates reached 38.0% and 30.7%, respectively, indicating no enhancing benefit of VB12 for F-53B under the studied conditions. Nominal-mass LC-MS/MS features consistent with partially defluorinated and hydrogen-substituted products were observed, and tentative transformation pathways were proposed. These results demonstrated compound-specific effects of VB12 and emphasized the distinction among loss, transformation and defluorination when evaluating PFAS destruction.
SN - 2305-6304
ER -