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Peer-reviewedCC BY 4.0Japanese Journal of Radiology

Imaging of benign salivary gland tumors under the fifth WHO classification, with a focus on rare histologic types and newly listed entities—Part II

  • Tohru Takeshita1
  • Taro Shimono2
  • Hirotaka Takita2
  • Daiju Ueda2,3
  • Kayo Ueda4
  • Yukio Miki2
  • Akira Yamamoto2
4 affiliations
  1. 1Department of Radiology, Osaka Habikino Medical Center, 3-7-1, Habikino, Habikino, Osaka City, 583-8588 Japan
  2. 2Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3, Asahi-Machi, Abeno-ku, Osaka, 545-8585 Japan
  3. 3Department of Artificial Intelligence, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan
  4. 4Department of Pathology, Osaka Habikino Medical Center, 3-7-1, Habikino, Habikino, Osaka, 583-8588 Japan
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Abstract

The World Health Organization (WHO) Classification of Head and Neck Tumors was updated from the fourth edition (published in 2017) to the fifth edition (published in 2024). The current WHO classification lists 15 benign and 21 malignant epithelial salivary gland tumors (SGTs). Among the benign epithelial tumors, four entities are newly listed: intercalated duct adenoma/hyperplasia, striated duct adenoma, sclerosing polycystic adenoma, and keratocystoma. This second article in a two-part review series summarizes the four newly listed benign SGTs, focusing on their classification background, clinicopathologic features, and reported imaging findings. As the published imaging literature remains limited, radiologic-pathologic correlation remains essential for recognizing these rare entities and avoiding overinterpretation of benign lesions. The aims of this review are to clarify the currently recognized imaging features of these rare tumors while emphasizing the need for careful integration of imaging, histopathologic, immunohistochemical, and molecular findings.

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Cite

BibTeXRIS
BibTeX
@article{takeshita2026imaging,
  title = {{Imaging of benign salivary gland tumors under the fifth WHO classification, with a focus on rare histologic types and newly listed entities—Part II}},
  author = {Tohru Takeshita and Taro Shimono and Hirotaka Takita and Daiju Ueda and Kayo Ueda and Yukio Miki and Akira Yamamoto},
  journal = {Japanese Journal of Radiology},
  year = {2026},
  month = jul,
  doi = {10.1007/s11604-026-02055-w},
  url = {https://doi.org/10.1007/s11604-026-02055-w},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Imaging of benign salivary gland tumors under the fifth WHO classification, with a focus on rare histologic types and newly listed entities—Part II
AU  - Tohru Takeshita
AU  - Taro Shimono
AU  - Hirotaka Takita
AU  - Daiju Ueda
AU  - Kayo Ueda
AU  - Yukio Miki
AU  - Akira Yamamoto
PY  - 2026
DA  - 2026/07/22
JO  - Japanese Journal of Radiology
DO  - 10.1007/s11604-026-02055-w
UR  - https://doi.org/10.1007/s11604-026-02055-w
AB  - The World Health Organization (WHO) Classification of Head and Neck Tumors was updated from the fourth edition (published in 2017) to the fifth edition (published in 2024). The current WHO classification lists 15 benign and 21 malignant epithelial salivary gland tumors (SGTs). Among the benign epithelial tumors, four entities are newly listed: intercalated duct adenoma/hyperplasia, striated duct adenoma, sclerosing polycystic adenoma, and keratocystoma. This second article in a two-part review series summarizes the four newly listed benign SGTs, focusing on their classification background, clinicopathologic features, and reported imaging findings. As the published imaging literature remains limited, radiologic-pathologic correlation remains essential for recognizing these rare entities and avoiding overinterpretation of benign lesions. The aims of this review are to clarify the currently recognized imaging features of these rare tumors while emphasizing the need for careful integration of imaging, histopathologic, immunohistochemical, and molecular findings.
SN  - 1867-1071
SN  - 1867-108X
ER  -