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PreprintCC BY 4.0arXiv

Design-Assisted Regression

Abstract

We consider regression problems in which the marginal distribution of the covariates is informative for estimation and variable selection, rather than merely auxiliary. Motivated by random-design, high-dimensional, and latent-effect settings, we propose a general design-assisted regression framework in which the estimating criterion depends on both the conditional model for Y | bfX and structured features of the covariate distribution. The framework identifies two roles of design information: stabilizing weak design directions through quadratic regularization and correcting latent-effect distortion through nuisance augmentation. We establish oracle properties for the resulting estimator, separate the effects of stochastic error, shrinkage, and approximation, and compare it with a benchmark sparse procedure that ignores design information. These results show that the proposed framework improves estimation while preserving first-order prediction performance. Numerical studies and two real-data applications illustrate the practical impact of incorporating design information.

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BibTeX
@misc{ye2026designassisted,
  title = {{Design-Assisted Regression}},
  author = {Shangyuan Ye and Guanbo Wang and Cong Zhang and Ye Liang},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2609.12886},
  eprint = {2609.12886},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2609.12886},
  note = {CC BY 4.0},
}
RIS
TY  - UNPB
TI  - Design-Assisted Regression
AU  - Shangyuan Ye
AU  - Guanbo Wang
AU  - Cong Zhang
AU  - Ye Liang
PY  - 2026
DA  - 2026/09/11
PB  - arXiv
DO  - 10.48550/arxiv.2609.12886
UR  - https://arxiv.org/abs/2609.12886
AB  - We consider regression problems in which the marginal distribution of the covariates is informative for estimation and variable selection, rather than merely auxiliary. Motivated by random-design, high-dimensional, and latent-effect settings, we propose a general design-assisted regression framework in which the estimating criterion depends on both the conditional model for Y | bfX and structured features of the covariate distribution. The framework identifies two roles of design information: stabilizing weak design directions through quadratic regularization and correcting latent-effect distortion through nuisance augmentation. We establish oracle properties for the resulting estimator, separate the effects of stochastic error, shrinkage, and approximation, and compare it with a benchmark sparse procedure that ignores design information. These results show that the proposed framework improves estimation while preserving first-order prediction performance. Numerical studies and two real-data applications illustrate the practical impact of incorporating design information.
ER  -