Imaging Characteristics and Differential Diagnosis of Newborn Oral Tumors Based on a Prenatally Diagnosed Neumann Tumor.
8 affiliations
- 1Pediatric Center, Semmelweis University, 1083 Budapest, Hungary.
- 2Department of Obstetrics and Gynecology, Semmelweis University, 1083 Budapest, Hungary.
- 3Institute of Anesthesiology and Perioperative Care, Semmelweis University, 1083 Budapest, Hungary.
- 4Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, 1083 Budapest, Hungary.
- 5Division of Histology and Embryology, Department of Biostructure and Animal Physiology, Wrocław University of Environmental and Life Sciences, Cypriana K. Norwida 25, 50-375 Wrocław, Poland.
- 6Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Aydın Adnan Menderes University, 09100 Aydın, Türkiye.
- 7Diagnostic Imaging Center, Borsod-Abaúj-Zemplén County Central Hospital and University Teaching Hospital, Szentpéteri kapu 72-76, 3526 Miskolc, Hungary.
- 8Maxillo-Facial Surgery Ward, EMC Hospital, Pilczycka 144, 54-144 Wrocław, Poland.
Abstract
The spectrum of congenital lesions in newborns includes various soft and hard tissue masses found within or near the oral cavity. While oral clefts are often easily diagnosed prenatally and treated after birth, other critical conditions may require immediate neonatal intervention. These include airway compromise resulting from choanal atresia, alveolar mucosal fusion, or space-occupying lesions that reduce airway volume. Furthermore, some lesions may cause significant bleeding or interfere with sucking and feeding. In such cases, careful prenatal evaluation using ultrasound (USG) and magnetic resonance (MR) imaging is essential to inform the timing and strategy of surgical interventions. The occurrence of a rare lesion, such as a congenital epulis, also known as a Neumann tumor (NT), requires precise diagnostics to exclude other worrisome pathologies. Detailed MR evaluation of the oral commissure, tongue, lips, and gingival area helps identify the lesion's extent and its anatomical relationship with adjacent structures. Although serial ultrasonography demonstrated interval growth, near-term MRI showed no pharyngeal extension or laryngotracheal narrowing. An EXIT-to-airway procedure was not planned, and delivery was performed by elective cesarean section with multidisciplinary airway support available. This report highlights that local NT removal typically focuses on complete excision, evaluation of the tumor base, and assessment of the surrounding alveolar bone.
Related
- Perinatal multidisciplinary management for neonates with prenatally-diagnosed congenital complete heart block undergoing early epicardial pacemaker implantation: a retrospective single-center case series
- The diagnostic value of quantitative 99mTc-MDP SPECT/CT fusion imaging in the differential diagnosis of spinal infections
- Correlation Between the Age at Menarche, Time to Diagnosis, and Disease Severity Assessed Using the rASRM and #ENZIAN Classifications in Patients Diagnosed with Advanced Endometriosis
- Structural Brain Imaging for Newly Diagnosed Cognitive Impairment by Medicare Coverage Type
- Newly diagnosed and relapsed follicular lymphoma: EHA Clinical Practice Guidelines for diagnosis, treatment, and follow-up.
BibTeX
@article{nagy2026imaging,
title = {{Imaging Characteristics and Differential Diagnosis of Newborn Oral Tumors Based on a Prenatally Diagnosed Neumann Tumor.}},
author = {Krisztián Nagy and Zsuzsanna Nagy and Agnes Kothencz and Gergő Leipold and Gergő Göbl and Tibor Glasz and Piotr Kuropka and Ömer Uranbey and Andrea Lakatos and Kamil Nelke},
journal = {Diagnostics (Basel, Switzerland)},
year = {2026},
month = sep,
doi = {10.3390/diagnostics16193131},
url = {https://europepmc.org/article/MED/42882286},
note = {CC BY},
}
RIS
TY - JOUR
TI - Imaging Characteristics and Differential Diagnosis of Newborn Oral Tumors Based on a Prenatally Diagnosed Neumann Tumor.
AU - Krisztián Nagy
AU - Zsuzsanna Nagy
AU - Agnes Kothencz
AU - Gergő Leipold
AU - Gergő Göbl
AU - Tibor Glasz
AU - Piotr Kuropka
AU - Ömer Uranbey
AU - Andrea Lakatos
AU - Kamil Nelke
PY - 2026
DA - 2026/09/26
JO - Diagnostics (Basel, Switzerland)
DO - 10.3390/diagnostics16193131
UR - https://europepmc.org/article/MED/42882286
AB - The spectrum of congenital lesions in newborns includes various soft and hard tissue masses found within or near the oral cavity. While oral clefts are often easily diagnosed prenatally and treated after birth, other critical conditions may require immediate neonatal intervention. These include airway compromise resulting from choanal atresia, alveolar mucosal fusion, or space-occupying lesions that reduce airway volume. Furthermore, some lesions may cause significant bleeding or interfere with sucking and feeding. In such cases, careful prenatal evaluation using ultrasound (USG) and magnetic resonance (MR) imaging is essential to inform the timing and strategy of surgical interventions. The occurrence of a rare lesion, such as a congenital epulis, also known as a Neumann tumor (NT), requires precise diagnostics to exclude other worrisome pathologies. Detailed MR evaluation of the oral commissure, tongue, lips, and gingival area helps identify the lesion's extent and its anatomical relationship with adjacent structures. Although serial ultrasonography demonstrated interval growth, near-term MRI showed no pharyngeal extension or laryngotracheal narrowing. An EXIT-to-airway procedure was not planned, and delivery was performed by elective cesarean section with multidisciplinary airway support available. This report highlights that local NT removal typically focuses on complete excision, evaluation of the tumor base, and assessment of the surrounding alveolar bone.
SN - 2075-4418
ER -