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Peer-reviewedCC BYClinical case reports

Giant Cervicothoracic Ganglioneuroma Misdiagnosed as Neurofibroma on Core Needle Biopsy: Transcervical Resection and Postoperative Neurological Sequelae: A Case Report

  • Omar Daas1
  • Somaya Al Kiswani2
  • Mohammad Z Al-Qaisi3
  • Ahmad Daas4
  • Ashjan Al Shakkah5
  • Sohaib Salahat6
  • Abdullah Nofal7
7 affiliations
  1. 1Department of Medicine The University of Jordan Amman Jordan.
  2. 2Radiology Department King Hussein Cancer Center Amman Jordan.
  3. 3Radiology Department Hamad Medical Corporation Doha Qatar.
  4. 4Department of Neurosurgery Ibn al-Haytham Hospital Amman Jordan.
  5. 5Oncology Imaging Fellow, Radiology Department King Hussein Cancer Center Amman Jordan.
  6. 6Department of Medicine, Faculty of Medicine and Health Sciences An-Najah National University Nablus Palestine.
  7. 7Head of Diagnostic Radiology Department King Hussein Cancer Center Amman Jordan.
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Abstract

Ganglioneuroma (GN) may be misdiagnosed as neurofibroma when core needle biopsy samples only contain Schwannian stroma without mature ganglion cells. Even giant cervicothoracic GNs may be resectable through a transcervical approach alone. Recurrent laryngeal nerve palsy and Horner syndrome are foreseeable, anatomically predictable risks requiring dedicated preoperative counseling.

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Cite

BibTeXRIS
BibTeX
@article{daas2026giant,
  title = {{Giant Cervicothoracic Ganglioneuroma Misdiagnosed as Neurofibroma on Core Needle Biopsy: Transcervical Resection and Postoperative Neurological Sequelae: A Case Report}},
  author = {Omar Daas and Somaya Al Kiswani and Mohammad Z Al-Qaisi and Ahmad Daas and Ashjan Al Shakkah and Sohaib Salahat and Abdullah Nofal},
  journal = {Clinical case reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73816},
  url = {https://europepmc.org/article/PMC/PMC13717949},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Giant Cervicothoracic Ganglioneuroma Misdiagnosed as Neurofibroma on Core Needle Biopsy: Transcervical Resection and Postoperative Neurological Sequelae: A Case Report
AU  - Omar Daas
AU  - Somaya Al Kiswani
AU  - Mohammad Z Al-Qaisi
AU  - Ahmad Daas
AU  - Ashjan Al Shakkah
AU  - Sohaib Salahat
AU  - Abdullah Nofal
PY  - 2026
DA  - 2026/10/29
JO  - Clinical case reports
DO  - 10.1002/ccr3.73816
UR  - https://europepmc.org/article/PMC/PMC13717949
AB  - Ganglioneuroma (GN) may be misdiagnosed as neurofibroma when core needle biopsy samples only contain Schwannian stroma without mature ganglion cells. Even giant cervicothoracic GNs may be resectable through a transcervical approach alone. Recurrent laryngeal nerve palsy and Horner syndrome are foreseeable, anatomically predictable risks requiring dedicated preoperative counseling.
SN  - 2050-0904
ER  -