Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 43 min ago
Peer-reviewedCC BYLaryngoscope Investigative Otolaryngology

Transcervical Epiglottic Suspension for Severe Type III Laryngomalacia in Infants: Feasibility, Safety, and Effectiveness

  1. 1Department of Otolaryngology–Head and Neck Surgery Children's Hospital Affiliated to Zhengzhou University (Henan Children's Hospital, Zhengzhou Children's Hospital), Henan Province Engineering Research Center of Early Diagnosis and Precise Treatment of Sleep Disordered Breathing Zhengzhou China
  2. 2Department of Otolaryngology–Head and Neck Surgery, Beijing Children's Hospital Capital Medical University, Beijing Key Laboratory for Pediatric Diseases of Otorhinolaryngology Head and Neck Surgery, National Center for Children's Health (NCCH) Beijing China

Abstract

Objective To evaluate the feasibility, safety, and clinical outcomes of transcervical epiglottic suspension in respiratory support‐dependent infants with Type III laryngomalacia. Methods This retrospective case series at a single‐center tertiary children's hospital included consecutive infants with endoscopically confirmed Type III laryngomalacia who were dependent on respiratory support because of upper airway obstruction. These infants underwent transcervical epiglottic suspension between January 1, 2024, and December 31, 2025. Because all eligible infants treated during the study period were included, no a priori sample size calculation was performed. Outcomes included procedural success, operative time, suture duration, perioperative complications, liberation from respiratory support, avoidance of tracheostomy, improvement in airway obstruction, feeding recovery, and catch‐up growth. Results Fifteen infants were included. Median age at surgery was 58 days. Primary procedural success was achieved in 14 of 15 infants and in all infants after revision. All infants were liberated from respiratory support, and none required tracheostomy. Airway obstruction scores improved significantly after surgery (p < 0.001). Median operative time was 20 min, median blood loss was 1 mL, median suture duration was 35 days, and median time to full oral feeding was 35 days. Among 10 infants with preoperative growth impairment, eight achieved normal weight‐for‐age status at final follow‐up. Adverse events included premature suture detachment in two infants and minor cutaneous pressure injury in one infant; no severe complications occurred. Conclusion Transcervical epiglottic suspension was feasible and was associated with rapid liberation from respiratory support and an acceptable safety profile in high‐risk infants with Type III laryngomalacia. Level of Evidence 4

Related

  1. How to … Do Feasibility, Acceptability and Potential Effectiveness Studies in Health Professions Education Research
    John Sandars
    The clinical teacherPeer-reviewedCC BYFull textEpidemiology & public healthEurope PMCEurope PMCPMC
  2. Feasibility and Preliminary Effectiveness of a Health and Wellbeing Intervention for Adults With Mild to Moderate Intellectual Disabilities.
    Helen McCready, Ken van Someren, Ben Fitzpatrick
    Journal of applied research in intellectual disabilities : JARIDPeer-reviewedCC BYFull textEpidemiology & public healthEurope PMC
  3. Giant Cervicothoracic Ganglioneuroma Misdiagnosed as Neurofibroma on Core Needle Biopsy: Transcervical Resection and Postoperative Neurological Sequelae: A Case Report
    Omar Daas, Somaya Al Kiswani, Mohammad Z Al-Qaisi +4
    Clinical case reportsPeer-reviewedCC BYFull textNeurologyEurope PMCEurope PMCPMC
  4. Evaluating the Feasibility, Acceptability, and Preliminary Effectiveness of Interprofessional Enhanced Cognitive Behavior Therapy for Anorexia Nervosa and Atypical Anorexia Nervosa: A Pilot Study
    Megan Bray, Gabriella Heruc, Susan Byrne +2
    The International Journal of Eating DisordersPeer-reviewedCC BY-NC 4.0Full textPsychiatry & mental healthPMC
  5. Feasibility and Preliminary Effectiveness of a Data-to-Care Intervention for HIV-Positive People Who Inject Drugs in Ukraine: A Pilot Cluster-Randomized Trial
    Kostyantyn Dumchev, Brian Weir, Khushee Prasad +6
    AIDS and behaviorPeer-reviewedCC BY-NC-ND 4.0Full textInfectious diseasePMC
BibTeX
@article{yang2026transcervical,
  title = {{Transcervical Epiglottic Suspension for Severe Type III Laryngomalacia in Infants: Feasibility, Safety, and Effectiveness}},
  author = {Weiguang Yang and Qingchuan Duan and Fei Zhang and Lan Jiang and Dongjie Seng and Ying Xu and Jie Zhang},
  journal = {Laryngoscope Investigative Otolaryngology},
  year = {2026},
  month = oct,
  doi = {10.1002/lio2.70584},
  url = {https://doi.org/10.1002/lio2.70584},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Transcervical Epiglottic Suspension for Severe Type III Laryngomalacia in Infants: Feasibility, Safety, and Effectiveness
AU  - Weiguang Yang
AU  - Qingchuan Duan
AU  - Fei Zhang
AU  - Lan Jiang
AU  - Dongjie Seng
AU  - Ying Xu
AU  - Jie Zhang
PY  - 2026
DA  - 2026/10/28
JO  - Laryngoscope Investigative Otolaryngology
DO  - 10.1002/lio2.70584
UR  - https://doi.org/10.1002/lio2.70584
AB  - Objective To evaluate the feasibility, safety, and clinical outcomes of transcervical epiglottic suspension in respiratory support‐dependent infants with Type III laryngomalacia. Methods This retrospective case series at a single‐center tertiary children's hospital included consecutive infants with endoscopically confirmed Type III laryngomalacia who were dependent on respiratory support because of upper airway obstruction. These infants underwent transcervical epiglottic suspension between January 1, 2024, and December 31, 2025. Because all eligible infants treated during the study period were included, no a priori sample size calculation was performed. Outcomes included procedural success, operative time, suture duration, perioperative complications, liberation from respiratory support, avoidance of tracheostomy, improvement in airway obstruction, feeding recovery, and catch‐up growth. Results Fifteen infants were included. Median age at surgery was 58 days. Primary procedural success was achieved in 14 of 15 infants and in all infants after revision. All infants were liberated from respiratory support, and none required tracheostomy. Airway obstruction scores improved significantly after surgery (p < 0.001). Median operative time was 20 min, median blood loss was 1 mL, median suture duration was 35 days, and median time to full oral feeding was 35 days. Among 10 infants with preoperative growth impairment, eight achieved normal weight‐for‐age status at final follow‐up. Adverse events included premature suture detachment in two infants and minor cutaneous pressure injury in one infant; no severe complications occurred. Conclusion Transcervical epiglottic suspension was feasible and was associated with rapid liberation from respiratory support and an acceptable safety profile in high‐risk infants with Type III laryngomalacia. Level of Evidence 4
SN  - 2378-8038
ER  -