Do participant testimony videos make people more interested in taking part in a clinical trial? A randomised Study Within a Trial (SWAT), registration SWAT203
Abstract
Background: Potentially eligible participants do not always agree to take part in trials when approached, which makes recruitment more challenging, time-consuming, and costly. We conducted a Study Within a Trial (SWAT) to evaluate whether showing people brief video testimonies about taking part in research increased their interest in participating.
Methods: The host trial was a randomised controlled trial of a digital intervention for paranoia (STOP; Successful Treatment of Paranoia). People who were referred to the host trial and opted to receive an online version of the Participant Information Sheet were eligible for enrolment into the SWAT. Before accessing the online Participant Information Sheet, people were randomly allocated to watch either a brief online video with participant testimonies about taking part in physical health research (generic), mental health research (tailored to topic of host trial), or a no video control. We collected data on who expressed interest in taking part, and who went on to be randomised into the trial in each condition.
Results: Four hundred eighty people took part in the SWAT (generic video = 62, tailored video = 188, no video = 230). People who were shown a video (of either type) were significantly more likely to express an interest in participating (OR 1.45; 95% CI, 1.02 to 2.09) compared to people who were not shown a video. However, the generic video was more effective than the tailored video in increasing the likelihood that someone would express interest in the trial (OR 2.52; 95% CI, 1.38 to 4.72).
Conclusions: Videos of participant testimonies led to enhanced interest in participating in the trial. Further research is needed to better understand the benefits or drawbacks associated with using generic vs. tailored patient testimony videos for different areas of health research.
Trial registration: SWAT 203: The effect of patient testimony videos on recruitment to a clinical trial. Registered on 18 November 2021 on the SWAT Repository Store hosted by The Northern Ireland Network for Trials Methodology Research (MRC Hubs for Trials Methodology Research) SWAT Store | The Northern Ireland Network for Trials Methodology Research (qub.ac.uk).
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BibTeX
@article{teale2026participant,
title = {{Do participant testimony videos make people more interested in taking part in a clinical trial? A randomised Study Within a Trial (SWAT), registration SWAT203}},
author = {Ashley-Louise Teale and Shadi Daryan and Carolina Fialho and Chloe Hampshire and Tanya Ricci and Rayan Taher and Jenny Yiend and Pamela Jacobsen},
journal = {Trials},
year = {2026},
month = oct,
doi = {10.1186/s13063-026-10042-9},
url = {https://link.springer.com/10.1186/s13063-026-10042-9},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Do participant testimony videos make people more interested in taking part in a clinical trial? A randomised Study Within a Trial (SWAT), registration SWAT203
AU - Ashley-Louise Teale
AU - Shadi Daryan
AU - Carolina Fialho
AU - Chloe Hampshire
AU - Tanya Ricci
AU - Rayan Taher
AU - Jenny Yiend
AU - Pamela Jacobsen
PY - 2026
DA - 2026/10/07
JO - Trials
DO - 10.1186/s13063-026-10042-9
UR - https://link.springer.com/10.1186/s13063-026-10042-9
AB - Background: Potentially eligible participants do not always agree to take part in trials when approached, which makes recruitment more challenging, time-consuming, and costly. We conducted a Study Within a Trial (SWAT) to evaluate whether showing people brief video testimonies about taking part in research increased their interest in participating. Methods: The host trial was a randomised controlled trial of a digital intervention for paranoia (STOP; Successful Treatment of Paranoia). People who were referred to the host trial and opted to receive an online version of the Participant Information Sheet were eligible for enrolment into the SWAT. Before accessing the online Participant Information Sheet, people were randomly allocated to watch either a brief online video with participant testimonies about taking part in physical health research (generic), mental health research (tailored to topic of host trial), or a no video control. We collected data on who expressed interest in taking part, and who went on to be randomised into the trial in each condition. Results: Four hundred eighty people took part in the SWAT (generic video = 62, tailored video = 188, no video = 230). People who were shown a video (of either type) were significantly more likely to express an interest in participating (OR 1.45; 95% CI, 1.02 to 2.09) compared to people who were not shown a video. However, the generic video was more effective than the tailored video in increasing the likelihood that someone would express interest in the trial (OR 2.52; 95% CI, 1.38 to 4.72). Conclusions: Videos of participant testimonies led to enhanced interest in participating in the trial. Further research is needed to better understand the benefits or drawbacks associated with using generic vs. tailored patient testimony videos for different areas of health research. Trial registration: SWAT 203: The effect of patient testimony videos on recruitment to a clinical trial. Registered on 18 November 2021 on the SWAT Repository Store hosted by The Northern Ireland Network for Trials Methodology Research (MRC Hubs for Trials Methodology Research) SWAT Store | The Northern Ireland Network for Trials Methodology Research (qub.ac.uk).
SN - 1745-6215
ER -