High-grade thoracic intradural extramedullary solitary fibrous tumor: A case report and literature review.
- 1Spine Surgery Service, Clínica Sebastián de Belalcázar, Clínica Colsanitas, Cali, Colombia.
- 2Faculty Member, Orthopedics and Traumatology Residency Program, Pontificia Universidad Javeriana, Cali, Colombia.
Abstract
Background
Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm of the central nervous system. Spinal intradural extramedullary SFT is particularly rare and can resemble more common lesions, including meningioma and schwannoma, on preoperative imaging.Case description
A 57-year-old female presented with a 5-month history of progressive motor and sensory thoracic paraparesis. Magnetic resonance imaging demonstrated a 34 × 15 × 10 mm intradural extramedullary mass extending from T3 to T5 with marked spinal cord compression. Surgery included T3-T4 laminectomy, durotomy, microsurgical tumor resection, and T2-T5 posterior instrumented fusion. Subtotal resection was performed because of nerve-root infiltration. Histopathology demonstrated a grade 3 SFT with focal necrosis, up to 6 mitoses per 10 high-power fields, a Ki-67 index of approximately 20%, and diffuse signal transducer and activator of transcription 6 positivity. Two months postoperatively, the patient ambulated independently with 5/5 motor function, residual L5-distribution dysesthesia, and preserved continence.Conclusion
High-grade spinal intradural extramedullary SFT is rare; histopathological and immunohistochemical confirmation is essential, and high-grade histology with subtotal resection warrants prolonged surveillance and multidisciplinary evaluation of adjuvant therapy.
Related
- A Rare Case of Distant Intradural Extramedullary Thoracic Metastasis from an Intracranial Solitary Fibrous Tumor
- A Giant Thoracic Mass and Hypoglycemia: Suspected Solitary Fibrous Tumor-related Doege-Potter Syndrome
- Intradural extramedullary venous hemangioma mimicking meningioma: a case report and literature review.
- Spinal subependymoma mimicking an intradural extramedullary tumor: illustrative case.
- First reported case of intradural extramedullary epithelioid hemangioma of the cauda equina: resection of an extremely rare vascular neoplasm. Illustrative case
BibTeX
@article{fuertesbolanos2026highgrade,
title = {{High-grade thoracic intradural extramedullary solitary fibrous tumor: A case report and literature review.}},
author = {Dario Fernando Fuertes-Bolaños and Yoston Felipe Ramírez-Capuano and Daniel Ortiz},
journal = {Surgical neurology international},
year = {2026},
month = oct,
doi = {10.25259/sni_1055_2026},
url = {https://europepmc.org/article/MED/42974553},
note = {CC BY-NC-SA},
}
RIS
TY - JOUR
TI - High-grade thoracic intradural extramedullary solitary fibrous tumor: A case report and literature review.
AU - Dario Fernando Fuertes-Bolaños
AU - Yoston Felipe Ramírez-Capuano
AU - Daniel Ortiz
PY - 2026
DA - 2026/10/30
JO - Surgical neurology international
DO - 10.25259/sni_1055_2026
UR - https://europepmc.org/article/MED/42974553
AB - Background Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm of the central nervous system. Spinal intradural extramedullary SFT is particularly rare and can resemble more common lesions, including meningioma and schwannoma, on preoperative imaging.Case description A 57-year-old female presented with a 5-month history of progressive motor and sensory thoracic paraparesis. Magnetic resonance imaging demonstrated a 34 × 15 × 10 mm intradural extramedullary mass extending from T3 to T5 with marked spinal cord compression. Surgery included T3-T4 laminectomy, durotomy, microsurgical tumor resection, and T2-T5 posterior instrumented fusion. Subtotal resection was performed because of nerve-root infiltration. Histopathology demonstrated a grade 3 SFT with focal necrosis, up to 6 mitoses per 10 high-power fields, a Ki-67 index of approximately 20%, and diffuse signal transducer and activator of transcription 6 positivity. Two months postoperatively, the patient ambulated independently with 5/5 motor function, residual L5-distribution dysesthesia, and preserved continence.Conclusion High-grade spinal intradural extramedullary SFT is rare; histopathological and immunohistochemical confirmation is essential, and high-grade histology with subtotal resection warrants prolonged surveillance and multidisciplinary evaluation of adjuvant therapy.
SN - 2229-5097
SN - 2152-7806
ER -