A Giant Thoracic Mass and Hypoglycemia: Suspected Solitary Fibrous Tumor-related Doege-Potter Syndrome

Abstract

A 96-year-old woman was brought to the emergency department with impaired mobility and generalized edema. She appeared drowsy, and blood glucose testing demonstrated severe hypoglycemia (38 mg/dL). Chest radiography showed an opacity in the right lower lung field, and computed tomography revealed a large intrathoracic mass. Laboratory testing revealed low serum insulin and C-peptide levels, suggesting non-islet cell tumor hypoglycemia. She had previously been diagnosed with a solitary fibrous tumor via a percutaneous biopsy at another hospital. Corticosteroids and glucose supplementation resolved the recurrent hypoglycemia. In patients with hypoglycemic episodes without diabetes and abnormal chest radiographic opacities, Doege-Potter syndrome should be considered.

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BibTeX RIS

BibTeX

@article{miwa2026giant,
  title = {{A Giant Thoracic Mass and Hypoglycemia: Suspected Solitary Fibrous Tumor-related Doege-Potter Syndrome}},
  author = {Maki Miwa and Yuki Komatsu and Yuna Nagano and Richard H. Kaszynski and Mikio Nakajima},
  journal = {Internal Medicine},
  year = {2026},
  month = aug,
  doi = {10.2169/internalmedicine.7675-26},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7675-26/_article},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - A Giant Thoracic Mass and Hypoglycemia: Suspected Solitary Fibrous Tumor-related Doege-Potter Syndrome
AU  - Maki Miwa
AU  - Yuki Komatsu
AU  - Yuna Nagano
AU  - Richard H. Kaszynski
AU  - Mikio Nakajima
PY  - 2026
DA  - 2026/08/25
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.7675-26
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7675-26/_article
AB  - A 96-year-old woman was brought to the emergency department with impaired mobility and generalized edema. She appeared drowsy, and blood glucose testing demonstrated severe hypoglycemia (38 mg/dL). Chest radiography showed an opacity in the right lower lung field, and computed tomography revealed a large intrathoracic mass. Laboratory testing revealed low serum insulin and C-peptide levels, suggesting non-islet cell tumor hypoglycemia. She had previously been diagnosed with a solitary fibrous tumor via a percutaneous biopsy at another hospital. Corticosteroids and glucose supplementation resolved the recurrent hypoglycemia. In patients with hypoglycemic episodes without diabetes and abnormal chest radiographic opacities, Doege-Potter syndrome should be considered.
SN  - 1349-7235
SN  - 0918-2918
ER  -

Abstract

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