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Peer-reviewedCC BY-NC-NDBMC ophthalmology

Selective compartmental plication in small-angle convergence insufficiency exotropia: surgical outcomes and predictive model.

4 affiliations
  1. 1Tianjin Eye Hospital, 300020, Tianjin, China.
  2. 2Tianjin Key Lab of Ophthalmology and Visual Science, 300020, Tianjin, China.
  3. 3Tianjin Eye Hospital, 300020, Tianjin, China. [email protected].
  4. 4Tianjin Key Lab of Ophthalmology and Visual Science, 300020, Tianjin, China. [email protected].

Abstract

Purpose

This study aimed to evaluate a novel surgical approach combining unilateral lateral rectus recession (LRc) with compartmentalized inferior medial rectus plication (CIMRP) for treating small-angle (< 25 prism diopters, PD) convergence insufficiency intermittent exotropia (CI-IXT) in pediatric patients.Methods

A retrospective analysis was conducted on 69 pediatric CI-IXT patients (mean age: 8.13 ± 2.46 years; range: 4-14 years) who underwent unilateral LRc and CIMRP between September 2022 and January 2024 at Tianjin Eye Hospital. All patients completed a minimum 12-month follow-up (mean: 12.41 ± 1.42 months; range: 12-18 months). Outcomes including near and distance deviations, near-distance difference (NDD), control scores, stereopsis, and complications were assessed preoperatively and postoperatively at 1 day, 2 months, 6 months, and final follow-up (12-18 months). Surgical success was defined as an exodeviation ≤ 10 PD or esodeviation ≤ + 5 PD in primary gaze at distance and near, and NDD ≤ 8 PD.Results

The mean LRc amount was 7.08 ± 0.48 mm (range: 6.5-7.5 mm), and the mean CIMRP amount was 3.56 ± 0.39 mm (range: 3.0-4.0 mm). Significant reductions were observed in near exo-deviation (median: -30 [- 32, - 28] PD to - 12 [- 16, - 6] PD), distance deviation (- 20 [- 20, - 18] PD to - 6 [- 10, - 1] PD), and NDD (10 [10, 10] PD to 4 [4, 6] PD; all P < 0.001, Friedman test).Simple linear regression identified an exploratory association between CIMRP amount and corrected NDD (defined as preoperative NDD minus postoperative NDD): Corrected NDD = 5.973 × CIMRP (mm) - 12.48 (P < 0.0001, R² = 0.2042). This indicates that each 1 mm increase in plication amount was associated with an average increase of approximately 5.97 PD in NDD correction within the observed 3.0-4.0 mm range. Surgical success was achieved in 88.41% at both 2 and 6 months, decreasing slightly to 81.16% at the final follow-up. The overcorrection rate peaked at 8.7% at 2 months and subsequently stabilized at 2.9%, whereas the undercorrection rate gradually increased to 15.9%. Control scores and near stereoacuity improved significantly after surgery (P < 0.001 and P < 0.05, respectively).Conclusion

Unilateral LRc combined with CIMRP is an effective and safe approach for small angle CI-IXT (< 25 PD). Based on preliminary evidence from this exploratory analysis, we tentatively suggest CIMRP of ≥ 3.5 mm for preoperative NDD > 10 PD, pending prospective validation. While this targeted technique addresses convergence insufficiency with favorable outcomes, further comparative studies are needed to define its clinical role.

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BibTeX
@article{ding2026selective,
  title = {{Selective compartmental plication in small-angle convergence insufficiency exotropia: surgical outcomes and predictive model.}},
  author = {Juan Ding and Pin Zhu and Liping Chen and Rui Hao and Wei Zhang and Yueping Li},
  journal = {BMC ophthalmology},
  year = {2026},
  month = aug,
  doi = {10.1186/s12886-026-05164-2},
  url = {https://europepmc.org/article/MED/42958107},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Selective compartmental plication in small-angle convergence insufficiency exotropia: surgical outcomes and predictive model.
AU  - Juan Ding
AU  - Pin Zhu
AU  - Liping Chen
AU  - Rui Hao
AU  - Wei Zhang
AU  - Yueping Li
PY  - 2026
DA  - 2026/08/03
JO  - BMC ophthalmology
DO  - 10.1186/s12886-026-05164-2
UR  - https://europepmc.org/article/MED/42958107
AB  - Purpose  This study aimed to evaluate a novel surgical approach combining unilateral lateral rectus recession (LRc) with compartmentalized inferior medial rectus plication (CIMRP) for treating small-angle (< 25 prism diopters, PD) convergence insufficiency intermittent exotropia (CI-IXT) in pediatric patients.Methods  A retrospective analysis was conducted on 69 pediatric CI-IXT patients (mean age: 8.13 ± 2.46 years; range: 4-14 years) who underwent unilateral LRc and CIMRP between September 2022 and January 2024 at Tianjin Eye Hospital. All patients completed a minimum 12-month follow-up (mean: 12.41 ± 1.42 months; range: 12-18 months). Outcomes including near and distance deviations, near-distance difference (NDD), control scores, stereopsis, and complications were assessed preoperatively and postoperatively at 1 day, 2 months, 6 months, and final follow-up (12-18 months). Surgical success was defined as an exodeviation ≤ 10 PD or esodeviation ≤ + 5 PD in primary gaze at distance and near, and NDD ≤ 8 PD.Results  The mean LRc amount was 7.08 ± 0.48 mm (range: 6.5-7.5 mm), and the mean CIMRP amount was 3.56 ± 0.39 mm (range: 3.0-4.0 mm). Significant reductions were observed in near exo-deviation (median: -30 [- 32, - 28] PD to - 12 [- 16, - 6] PD), distance deviation (- 20 [- 20, - 18] PD to - 6 [- 10, - 1] PD), and NDD (10 [10, 10] PD to 4 [4, 6] PD; all P < 0.001, Friedman test).Simple linear regression identified an exploratory association between CIMRP amount and corrected NDD (defined as preoperative NDD minus postoperative NDD): Corrected NDD = 5.973 × CIMRP (mm) - 12.48 (P < 0.0001, R² = 0.2042). This indicates that each 1 mm increase in plication amount was associated with an average increase of approximately 5.97 PD in NDD correction within the observed 3.0-4.0 mm range. Surgical success was achieved in 88.41% at both 2 and 6 months, decreasing slightly to 81.16% at the final follow-up. The overcorrection rate peaked at 8.7% at 2 months and subsequently stabilized at 2.9%, whereas the undercorrection rate gradually increased to 15.9%. Control scores and near stereoacuity improved significantly after surgery (P < 0.001 and P < 0.05, respectively).Conclusion  Unilateral LRc combined with CIMRP is an effective and safe approach for small angle CI-IXT (< 25 PD). Based on preliminary evidence from this exploratory analysis, we tentatively suggest CIMRP of ≥ 3.5 mm for preoperative NDD > 10 PD, pending prospective validation. While this targeted technique addresses convergence insufficiency with favorable outcomes, further comparative studies are needed to define its clinical role.
SN  - 1471-2415
ER  -