Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 57 min ago
PreprintCC BYmedRxiv

The agrarian imperative as the foundation for how farmers and ranchers diagnosed with alpha-gal syndrome find meaning in their experience: A mixed methods approach

  1. 1University of Nebraska Medical Center

Abstract

The agrarian imperative is the drive of agricultural workers to use their land to provide for their families and communities, even when the environment is hazardous and success is often out of their control. Alpha-gal syndrome (AGS), an emerging tickborne allergy to mammalian derived products, is challenging the agrarian imperative by impacting the workers ability to maintain their operation. This study aimed to characterize farmers and ranchers experiences after receiving an AGS diagnosis related to their land and their work. Using the framework of the agrarian imperative theory and a mixed methods approach, we aimed to determine the impact on daily work tasks, the wellbeing burden of the diagnosis, the financial challenges of the operation and daily life, and dietary changes. Survey data from 201 farmers and ranchers diagnosed with AGS were analyzed alongside qualitative data from interviews with 14 participants. The respondents felt as though their wellbeing was affected, and felt distressed, depressed, and anxious. Anxiety was the most frequently reported mental health impact of AGS due to forced dietary changes, but distress was more highly associated with work factors. Nearly half of the sample were experiencing distress due to having to modify their work tasks and worrying about the productivity of the agricultural operation. We found agricultural operators with animals are more likely to experience greater work challenges. Maintaining a productive farm was the most important objective and reflects the agrarian imperative, but additional costs associated with AGS complicates their work and life.

Related

  1. Stem cell mobilization with G-CSF and on-demand plerixafor in newly diagnosed multiple myeloma patients treated with daratumumab: a single-center experience
    Barbara Skopec, Luka Cemazar, Matevz Skerget
    Frontiers in OncologyPeer-reviewedCC BY 4.0OncologyCrossref
  2. Histopathologic spectrum of focal liver lesions diagnosed by ultrasound-guided percutaneous liver biopsy and predictors of hepatocellular carcinoma: A single-center experience from Sub-Saharan Africa
    Tamrat Petros Elias, Abate Bane Shewaye, Kaleb Assefa Berhane +4
    PLOS OnePeer-reviewedCC BY 4.0Full textMicrobiologyMedical imaging & radiologyPLOS
  3. Digital Health: Improve Patient Care while Preserving the Planet, an Ethical Imperative
    Brigitte Séroussi
    Yearbook of Medical InformaticsPeer-reviewedCC BY 4.0Full textEpidemiology & public healthPMC
  4. Moving Beyond the Plateau in Immune Checkpoint Inhibition-The Imperative of Early Referral and Precision Strategies.
    Razelle Kurzrock
    Journal of immunotherapy and precision oncologyPeer-reviewedCC BY-NC-NDFull textOncologyEurope PMC
  5. Response to the Letter Regarding "If Becker Muscular Dystrophy Initially Manifests with Heart Disease and Rhabdomyolysis, Neurological Work-up Is Imperative"
    Kento Kumai, Hiroki Mochizuki, Takuya Watanabe +16
    Internal MedicinePeer-reviewedCC BY-NC-NDFull textSurgery & anaesthesiaJ-STAGE
BibTeX
@misc{welch2026agrarian,
  title = {{The agrarian imperative as the foundation for how farmers and ranchers diagnosed with alpha-gal syndrome find meaning in their experience: A mixed methods approach}},
  author = {A. M. Welch and C. L. Beseler and S. T. Cross},
  howpublished = {medRxiv},
  year = {2026},
  month = oct,
  doi = {10.64898/2026.10.29.26366631},
  url = {https://www.medrxiv.org/content/10.64898/2026.10.29.26366631v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - The agrarian imperative as the foundation for how farmers and ranchers diagnosed with alpha-gal syndrome find meaning in their experience: A mixed methods approach
AU  - A. M. Welch
AU  - C. L. Beseler
AU  - S. T. Cross
PY  - 2026
DA  - 2026/10/29
PB  - medRxiv
DO  - 10.64898/2026.10.29.26366631
UR  - https://www.medrxiv.org/content/10.64898/2026.10.29.26366631v1
AB  - The agrarian imperative is the drive of agricultural workers to use their land to provide for their families and communities, even when the environment is hazardous and success is often out of their control. Alpha-gal syndrome (AGS), an emerging tickborne allergy to mammalian derived products, is challenging the agrarian imperative by impacting the workers ability to maintain their operation. This study aimed to characterize farmers and ranchers experiences after receiving an AGS diagnosis related to their land and their work. Using the framework of the agrarian imperative theory and a mixed methods approach, we aimed to determine the impact on daily work tasks, the wellbeing burden of the diagnosis, the financial challenges of the operation and daily life, and dietary changes. Survey data from 201 farmers and ranchers diagnosed with AGS were analyzed alongside qualitative data from interviews with 14 participants. The respondents felt as though their wellbeing was affected, and felt distressed, depressed, and anxious. Anxiety was the most frequently reported mental health impact of AGS due to forced dietary changes, but distress was more highly associated with work factors. Nearly half of the sample were experiencing distress due to having to modify their work tasks and worrying about the productivity of the agricultural operation. We found agricultural operators with animals are more likely to experience greater work challenges. Maintaining a productive farm was the most important objective and reflects the agrarian imperative, but additional costs associated with AGS complicates their work and life.
ER  -