Patterns and correlates of HIV pre-exposure prophylaxis use among higher-risk men who have sex with men in the Jakarta Metropolitan Area, Indonesia
- 1The University of Hong Kong
Abstract
BackgroundMen who have sex with men (MSM) in the Jakarta Metropolitan Area (JMA), Indonesia are disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) is a viable strategy for addressing enduring HIV disparities, yet remains underutilized among MSM in the JMA. Patterns and influences of PrEP use may inform future intervention targets but have not been extensively studied in this context.
MethodsGuided by the Andersens Behavioral Model for Health Services Use, the present study investigated multidimensional correlates of varied PrEP use patterns among 183 JMA-based MSM aged 18-51 (median age=29) and at elevated risk of HIV infection. The multinomial regression model identified factors associated with current PrEP use and some use in the past, compared with never use (reference category).
ResultsIn the present study, 107 (58%) participants reported never use, 34 (19%) current use, and 42 (23%) some use of PrEP. Current PrEP use was negatively associated with HIV stigma and positively with perceived social support, online HIV information seeking, and sexualized drug use. Some PrEP use was negatively associated with HIV stigma and positively with online HIV information seeking.
ConclusionsThe study findings provide support for the Andersen models emphasis on predisposing characteristics, enabling resources, and need factors when tailoring PrEP implementation for higher-risk MSM in the JMA. Addressing stigma, reinforcing social support and HIV knowledge, and integrating PrEP care within multiple health care systems appear viable avenues for improving PrEP adoption in this key population.
Related
- Nationwide registry-based analysis of rabies exposures in Iran: Epidemiological patterns and post-exposure prophylaxis adherence
- Prevalence and correlates of depressive symptoms among Ethiopian and Ethiopian-Descent adults in the Seattle metropolitan area: A cross-sectional study
- From Structural Resources to Latent Protective Capacity: A Bayesian Multilevel Analysis of Flood Exposure and Depressive Symptoms in Indonesia
- Awareness and Prescribing Practices for Doxycycline Post‐Exposure Prophylaxis (doxyPEP) Among Healthcare Providers Delivering Sexual Health Care in Australia: A Cross‐Sectional Survey
- Less is more: reconsidering asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae screening for gay, bisexual and other men who have sex with men in the era of doxycycline post-exposure prophylaxis (DoxyPEP)
BibTeX
@misc{lee2026patterns,
title = {{Patterns and correlates of HIV pre-exposure prophylaxis use among higher-risk men who have sex with men in the Jakarta Metropolitan Area, Indonesia}},
author = {Y. G. Lee and L. Nevendorff and W. Reswana and T. Y. Wong and X. Yang and Y. Xu and C. Yang and Y. Huang and J. Oktavianus and E. Wu},
howpublished = {medRxiv},
year = {2026},
month = oct,
doi = {10.64898/2026.10.12.26364848},
url = {https://www.medrxiv.org/content/10.64898/2026.10.12.26364848v1},
note = {CC BY-NC-ND},
}
RIS
TY - UNPB
TI - Patterns and correlates of HIV pre-exposure prophylaxis use among higher-risk men who have sex with men in the Jakarta Metropolitan Area, Indonesia
AU - Y. G. Lee
AU - L. Nevendorff
AU - W. Reswana
AU - T. Y. Wong
AU - X. Yang
AU - Y. Xu
AU - C. Yang
AU - Y. Huang
AU - J. Oktavianus
AU - E. Wu
PY - 2026
DA - 2026/10/12
PB - medRxiv
DO - 10.64898/2026.10.12.26364848
UR - https://www.medrxiv.org/content/10.64898/2026.10.12.26364848v1
AB - BackgroundMen who have sex with men (MSM) in the Jakarta Metropolitan Area (JMA), Indonesia are disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) is a viable strategy for addressing enduring HIV disparities, yet remains underutilized among MSM in the JMA. Patterns and influences of PrEP use may inform future intervention targets but have not been extensively studied in this context. MethodsGuided by the Andersens Behavioral Model for Health Services Use, the present study investigated multidimensional correlates of varied PrEP use patterns among 183 JMA-based MSM aged 18-51 (median age=29) and at elevated risk of HIV infection. The multinomial regression model identified factors associated with current PrEP use and some use in the past, compared with never use (reference category). ResultsIn the present study, 107 (58%) participants reported never use, 34 (19%) current use, and 42 (23%) some use of PrEP. Current PrEP use was negatively associated with HIV stigma and positively with perceived social support, online HIV information seeking, and sexualized drug use. Some PrEP use was negatively associated with HIV stigma and positively with online HIV information seeking. ConclusionsThe study findings provide support for the Andersen models emphasis on predisposing characteristics, enabling resources, and need factors when tailoring PrEP implementation for higher-risk MSM in the JMA. Addressing stigma, reinforcing social support and HIV knowledge, and integrating PrEP care within multiple health care systems appear viable avenues for improving PrEP adoption in this key population.
ER -