Role of primary protectors of plant cells in salinity tolerance: molecular mechanisms and adaptive strategies
5 affiliations
- 1Department of Microbiology and Biotechnology, Sister Nivedita University (SNU)
- 2Department of Botany, MES Keveeyam College
- 3Faculty of Applied Ecology, Agricultural Science, and Biotechnology, University of Inland Norway
- 4Department of Biological and Environmental Sciences, University of Gothenburg
- 5Department of Horticultural Science, Faculty of Agriculture, Shahid Chamran University of Ahvaz
Abstract
Salinity stress is among the most pervasive abiotic factors limiting plant growth and agricultural productivity worldwide, currently affecting more than 20% of irrigated croplands. Elevated salt concentrations induce osmotic imbalance, ionic toxicity, and oxidative stress, leading to disruptions in photosynthesis, metabolism, and plant development. To counteract these deleterious effects, plants have evolved intricate, highly coordinated defense systems comprising structural and functional cellular protectors. At the structural level, the cell wall, plasma membrane, vacuole, and peroxisome play critical roles in maintaining cellular homeostasis under saline conditions. These cellular structures safeguard the cell by regulating ion fluxes, preserving membrane integrity, and mitigating the toxicity of reactive oxygen species (ROS). Ion transporters such as SOS1, NHX1, and HKT1, along with vacuolar proton pumps, maintain optimal Na⁺/K⁺ balance and pH regulation within cellular compartments. Functionally, plants deploy osmolytes and compatible solutes, including proline, glycine betaine, trehalose, and polyamines that act as osmoprotectants, stabilizing proteins and membranes while maintaining cellular turgor. Concurrently, robust antioxidant systems, comprising both enzymatic components (superoxide dismutase, catalase, ascorbate peroxidase) and non-enzymatic molecules (ascorbate, glutathione, carotenoids), scavenge excess ROS generated during salt stress. Stress proteins such as heat shock proteins (HSPs) and late embryogenesis abundant (LEA) proteins also contribute to proteostasis and membrane stabilization during salt stress. Recent advances (2020-2025) have significantly expanded our understanding of the molecular and signaling networks underlying salinity tolerance. While earlier studies have focused on individual components such as ion transporters, osmolytes, or antioxidant systems, this review uniquely integrates structural organelle-based defenses with functional metabolic responses into a unified framework. We highlight the dynamic cross-communication among transcriptional regulators, ion transport systems, ROS detoxification pathways, and hormonal signaling cascades that collectively orchestrate plant adaptation to salinity. By synthesizing recent findings from a systems-level perspective, this work provides novel insights into the coordinated cellular defense network, identifying key regulatory hubs and multi-target strategies for breeding and biotechnological interventions to improve crop resilience and productivity in salt-affected agroecosystems.
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BibTeX
@article{das2026role,
title = {{Role of primary protectors of plant cells in salinity tolerance: molecular mechanisms and adaptive strategies}},
author = {Susmita Das and Edappayil Janeeshma and Hesam Mousavi and Henrik Aronsson and Mohammad Sarraf},
journal = {Plant Signaling \& Behavior},
year = {2026},
month = jun,
doi = {10.1080/15592324.2026.2687962},
url = {https://doi.org/10.1080/15592324.2026.2687962},
note = {CC BY},
}
RIS
TY - JOUR
TI - Role of primary protectors of plant cells in salinity tolerance: molecular mechanisms and adaptive strategies
AU - Susmita Das
AU - Edappayil Janeeshma
AU - Hesam Mousavi
AU - Henrik Aronsson
AU - Mohammad Sarraf
PY - 2026
DA - 2026/06/12
JO - Plant Signaling & Behavior
DO - 10.1080/15592324.2026.2687962
UR - https://doi.org/10.1080/15592324.2026.2687962
AB - Salinity stress is among the most pervasive abiotic factors limiting plant growth and agricultural productivity worldwide, currently affecting more than 20% of irrigated croplands. Elevated salt concentrations induce osmotic imbalance, ionic toxicity, and oxidative stress, leading to disruptions in photosynthesis, metabolism, and plant development. To counteract these deleterious effects, plants have evolved intricate, highly coordinated defense systems comprising structural and functional cellular protectors. At the structural level, the cell wall, plasma membrane, vacuole, and peroxisome play critical roles in maintaining cellular homeostasis under saline conditions. These cellular structures safeguard the cell by regulating ion fluxes, preserving membrane integrity, and mitigating the toxicity of reactive oxygen species (ROS). Ion transporters such as SOS1, NHX1, and HKT1, along with vacuolar proton pumps, maintain optimal Na⁺/K⁺ balance and pH regulation within cellular compartments. Functionally, plants deploy osmolytes and compatible solutes, including proline, glycine betaine, trehalose, and polyamines that act as osmoprotectants, stabilizing proteins and membranes while maintaining cellular turgor. Concurrently, robust antioxidant systems, comprising both enzymatic components (superoxide dismutase, catalase, ascorbate peroxidase) and non-enzymatic molecules (ascorbate, glutathione, carotenoids), scavenge excess ROS generated during salt stress. Stress proteins such as heat shock proteins (HSPs) and late embryogenesis abundant (LEA) proteins also contribute to proteostasis and membrane stabilization during salt stress. Recent advances (2020-2025) have significantly expanded our understanding of the molecular and signaling networks underlying salinity tolerance. While earlier studies have focused on individual components such as ion transporters, osmolytes, or antioxidant systems, this review uniquely integrates structural organelle-based defenses with functional metabolic responses into a unified framework. We highlight the dynamic cross-communication among transcriptional regulators, ion transport systems, ROS detoxification pathways, and hormonal signaling cascades that collectively orchestrate plant adaptation to salinity. By synthesizing recent findings from a systems-level perspective, this work provides novel insights into the coordinated cellular defense network, identifying key regulatory hubs and multi-target strategies for breeding and biotechnological interventions to improve crop resilience and productivity in salt-affected agroecosystems.
SN - 1559-2316
SN - 1559-2324
ER -