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Peer-reviewedCC BYFrontiers in surgery

Factors associated with prolonged postoperative hospital stay after cholecystectomy for acute cholecystitis in a Peruvian emergency hospital.

  • Yudi N Tolentino-Alania1
  • Fiorella A Sanchez-Ubaldo2
  • Miguel A Arce-Huamani2
  1. 1Programa Académico de Medicina Humana, Facultad de Ciencias de la Salud, Universidad Privada San Juan Bautista, Lima, Peru.
  2. 2Programa Académico de Medicina Humana, Facultad de Ciencias de la Salud, Universidad Privada Norbert Wiener, Lima, Peru.
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Abstract

Prolonged postoperative hospital stay after cholecystectomy for acute cholecystitis may reflect baseline vulnerability and disease severity. We assessed preoperative factors associated with prolonged postoperative stay in a Peruvian emergency hospital. We conducted a retrospective cohort study of patients undergoing cholecystectomy for acute cholecystitis in 2024. All potentially eligible source records were screened. Prolonged postoperative stay was defined as >3 days from surgery to discharge. Adjusted risk ratios (aRRs) and 95% confidence intervals (CIs) were estimated using modified Poisson regression with robust variance in a prespecified model restricted to preoperative variables. Of 540 records screened, 422 patients were eligible. Median postoperative stay was 2.4 days (IQR, 1.0-3.8), and 158 patients (37.4%) stayed >3 days. Higher risk was observed for age 45-64 years (aRR, 1.51; 95% CI, 1.09-2.10), age ≥65 years (aRR, 1.95; 95% CI, 1.37-2.76), diabetes mellitus (aRR, 1.31; 95% CI, 1.02-1.67), and ASA IV-V status (aRR, 1.50; 95% CI, 1.04-2.16). Hypertension and active smoking showed inverse associations and require cautious interpretation. Postoperative complications occurred in 111 patients (26.3%) and were analyzed descriptively. Older age, diabetes mellitus, and higher preoperative ASA status were associated with prolonged postoperative stay. These findings warrant prospective validation and should not be interpreted as causal.

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Cite

BibTeXRIS
BibTeX
@article{tolentinoalania2026factors,
  title = {{Factors associated with prolonged postoperative hospital stay after cholecystectomy for acute cholecystitis in a Peruvian emergency hospital.}},
  author = {Yudi N Tolentino-Alania and Fiorella A Sanchez-Ubaldo and Miguel A Arce-Huamani},
  journal = {Frontiers in surgery},
  year = {2026},
  month = oct,
  doi = {10.3389/fsurg.2026.1921693},
  url = {https://europepmc.org/article/MED/42952932},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Factors associated with prolonged postoperative hospital stay after cholecystectomy for acute cholecystitis in a Peruvian emergency hospital.
AU  - Yudi N Tolentino-Alania
AU  - Fiorella A Sanchez-Ubaldo
AU  - Miguel A Arce-Huamani
PY  - 2026
DA  - 2026/10/14
JO  - Frontiers in surgery
DO  - 10.3389/fsurg.2026.1921693
UR  - https://europepmc.org/article/MED/42952932
AB  - Prolonged postoperative hospital stay after cholecystectomy for acute cholecystitis may reflect baseline vulnerability and disease severity. We assessed preoperative factors associated with prolonged postoperative stay in a Peruvian emergency hospital. We conducted a retrospective cohort study of patients undergoing cholecystectomy for acute cholecystitis in 2024. All potentially eligible source records were screened. Prolonged postoperative stay was defined as >3 days from surgery to discharge. Adjusted risk ratios (aRRs) and 95% confidence intervals (CIs) were estimated using modified Poisson regression with robust variance in a prespecified model restricted to preoperative variables. Of 540 records screened, 422 patients were eligible. Median postoperative stay was 2.4 days (IQR, 1.0-3.8), and 158 patients (37.4%) stayed >3 days. Higher risk was observed for age 45-64 years (aRR, 1.51; 95% CI, 1.09-2.10), age ≥65 years (aRR, 1.95; 95% CI, 1.37-2.76), diabetes mellitus (aRR, 1.31; 95% CI, 1.02-1.67), and ASA IV-V status (aRR, 1.50; 95% CI, 1.04-2.16). Hypertension and active smoking showed inverse associations and require cautious interpretation. Postoperative complications occurred in 111 patients (26.3%) and were analyzed descriptively. Older age, diabetes mellitus, and higher preoperative ASA status were associated with prolonged postoperative stay. These findings warrant prospective validation and should not be interpreted as causal.
SN  - 2296-875X
ER  -