Peer-reviewedCC BY-NC-NDMaterials Today
Tissue engineering by self-assembly
Abstract
A long-standing limitation in tissue engineering has been the dogmatic reliance on synthetic scaffolds for building tissues with significant mechanical functions despite their deleterious effects (inflammation, scarring, infection, etc.). Tissue engineering by self-assembly (TESA) is a novel approach that relies on the cell's ability to produce natural extracellular matrix TESA can be used to produce structures that have physiological strength and are not recognized as foreign in vivo. We have developed a tissue-engineered blood vessel that has shown great promise as an arteriovenous shunt. Here, we review our journey from bench-top to bedside and discuss future applications of the TESA approach.
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BibTeX
@article{peck2026tissue,
title = {{Tissue engineering by self-assembly}},
author = {Marissa Peck and Nathalie Dusserre and Todd Mcallister and Nicolas L'Heureux},
journal = {Materials Today},
year = {2026},
month = oct,
doi = {10.1016/s1369-7021(11)70117-1},
url = {https://hal.science/hal-05797634v1},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Tissue engineering by self-assembly
AU - Marissa Peck
AU - Nathalie Dusserre
AU - Todd Mcallister
AU - Nicolas L'Heureux
PY - 2026
DA - 2026/10/13
JO - Materials Today
DO - 10.1016/s1369-7021(11)70117-1
UR - https://hal.science/hal-05797634v1
AB - A long-standing limitation in tissue engineering has been the dogmatic reliance on synthetic scaffolds for building tissues with significant mechanical functions despite their deleterious effects (inflammation, scarring, infection, etc.). Tissue engineering by self-assembly (TESA) is a novel approach that relies on the cell's ability to produce natural extracellular matrix TESA can be used to produce structures that have physiological strength and are not recognized as foreign in vivo. We have developed a tissue-engineered blood vessel that has shown great promise as an arteriovenous shunt. Here, we review our journey from bench-top to bedside and discuss future applications of the TESA approach.
SN - 1369-7021
ER -