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Peer-reviewedCC BY 4.0Trends in Pharmacological Sciences

Why pharmacological concepts survive despite scientific progress

  • Pierre-Louis Toutain
  • Peggy Gandia
  • Didier Concordet
Open at sourcePDFDOICite

Abstract

Scientific disciplines routinely reassess methods but rarely the concepts guiding scientific reasoning. We identify three mechanisms of conceptual persistence: amnesia, institutionalisation, and reificationthe process by which an operational construct is regarded as biological reality. These mechanism s may impede scientific self-correction, a challenge increasingly relevant as artificial intelligence learns from scientific literature.

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Cite

BibTeXRIS
BibTeX
@article{toutain2026pharmacological,
  title = {{Why pharmacological concepts survive despite scientific progress}},
  author = {Pierre-Louis Toutain and Peggy Gandia and Didier Concordet},
  journal = {Trends in Pharmacological Sciences},
  year = {2026},
  month = oct,
  doi = {10.1016/j.tips.2026.08.008},
  url = {https://hal.science/hal-05797871v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Why pharmacological concepts survive despite scientific progress
AU  - Pierre-Louis Toutain
AU  - Peggy Gandia
AU  - Didier Concordet
PY  - 2026
DA  - 2026/10/13
JO  - Trends in Pharmacological Sciences
DO  - 10.1016/j.tips.2026.08.008
UR  - https://hal.science/hal-05797871v1
AB  - Scientific disciplines routinely reassess methods but rarely the concepts guiding scientific reasoning. We identify three mechanisms of conceptual persistence: amnesia, institutionalisation, and reificationthe process by which an operational construct is regarded as biological reality. These mechanism s may impede scientific self-correction, a challenge increasingly relevant as artificial intelligence learns from scientific literature.
SN  - 0165-6147
ER  -