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Peer-reviewedCC BYDiscover Public Health

Factors associated with microvascular complications in patients with type 2 diabetes in Mueang District, Phitsanulok Province

  1. 1Primary Care Center, Buddhachinaraj Phitsanulok Hospital
  2. 2Department of Environmental Health, School of Public Health, University of Phayao
  3. 3Sirindhorn College of Public Health Phitsanulok, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute

Abstract

Objective To identify factors associated with microvascular complications among patients with type 2 diabetes (T2DM) in Mueang District, Phitsanulok Province, Thailand. Materials and methods A hospital-based case-control study was conducted. A total of 390 patients were included, comprising 130 cases with physician-diagnosed microvascular complications and 260 controls without complications. Data were obtained from medical records and structured interviews covering age, duration of diabetes, antihyperglycemic medication use, glycated hemoglobin (HbA1c), blood pressure, dietary behavior, and perceived stress. Univariable and multivariable logistic regression analyses were performed to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results After adjustment, duration of diabetes ≥ 7 years was associated with increased odds of microvascular complications (adjusted OR [AOR] = 3.05; 95% CI: 1.52–6.15). Patients not receiving metformin (AOR = 108.02; 95% CI: 21.92-532.25) and those not receiving glipizide (AOR = 2.83; 95% CI: 1.59–5.06) had significantly higher odds. Elevated blood pressure ≥ 140/90 mmHg (AOR = 2.55; 95% CI: 1.40–4.65) and high perceived stress (AOR = 2.18; 95% CI: 1.01–4.74) were independently associated. Age > 60 years showed an inverse association (AOR = 0.20; 95% CI: 0.11–0.37). HbA1c level and dietary behavior were not significant after adjustment. Conclusion These findings suggest that sustained pharmacological treatment, blood pressure control, and psychosocial stress management are associated with the risk of microvascular complication among patients with T2DM.

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BibTeX
@article{kamolvoradej2026factors,
  title = {{Factors associated with microvascular complications in patients with type 2 diabetes in Mueang District, Phitsanulok Province}},
  author = {Nathamon Kamolvoradej and Patipat Vongruang and Sakesun Thongtip and Kongprai Tunsuchart},
  journal = {Discover Public Health},
  year = {2026},
  month = oct,
  doi = {10.1186/s12982-026-03187-0},
  url = {https://doi.org/10.1186/s12982-026-03187-0},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Factors associated with microvascular complications in patients with type 2 diabetes in Mueang District, Phitsanulok Province
AU  - Nathamon Kamolvoradej
AU  - Patipat Vongruang
AU  - Sakesun Thongtip
AU  - Kongprai Tunsuchart
PY  - 2026
DA  - 2026/10/25
JO  - Discover Public Health
DO  - 10.1186/s12982-026-03187-0
UR  - https://doi.org/10.1186/s12982-026-03187-0
AB  - Objective To identify factors associated with microvascular complications among patients with type 2 diabetes (T2DM) in Mueang District, Phitsanulok Province, Thailand. Materials and methods A hospital-based case-control study was conducted. A total of 390 patients were included, comprising 130 cases with physician-diagnosed microvascular complications and 260 controls without complications. Data were obtained from medical records and structured interviews covering age, duration of diabetes, antihyperglycemic medication use, glycated hemoglobin (HbA1c), blood pressure, dietary behavior, and perceived stress. Univariable and multivariable logistic regression analyses were performed to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results After adjustment, duration of diabetes ≥ 7 years was associated with increased odds of microvascular complications (adjusted OR [AOR] = 3.05; 95% CI: 1.52–6.15). Patients not receiving metformin (AOR = 108.02; 95% CI: 21.92-532.25) and those not receiving glipizide (AOR = 2.83; 95% CI: 1.59–5.06) had significantly higher odds. Elevated blood pressure ≥ 140/90 mmHg (AOR = 2.55; 95% CI: 1.40–4.65) and high perceived stress (AOR = 2.18; 95% CI: 1.01–4.74) were independently associated. Age > 60 years showed an inverse association (AOR = 0.20; 95% CI: 0.11–0.37). HbA1c level and dietary behavior were not significant after adjustment. Conclusion These findings suggest that sustained pharmacological treatment, blood pressure control, and psychosocial stress management are associated with the risk of microvascular complication among patients with T2DM.
SN  - 3005-0774
ER  -