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Peer-reviewedCC BY-NC-ND 4.0JACC Case Reports

Tailoring Antiplatelet Adherence

  • Rudra Pratap Singh1
  • Breandan Kelly2
  • Seerat Sachdeva3
  • Stephanie Rosenberg1
  • Harmon R. Cannon2
  • Linda Macdonald1
  1. 1Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA
  2. 2Division of Cardiology, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA
  3. 3Department of Neurology, University of New Mexico, Albuquerque, New Mexico, USA
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Abstract

Background: The use of P2Y12 inhibitor is highly variable, and administration is frequently confounded by inconsistent documentation that heightens risks for mismanagement, particularly following transitions of care.

Project Rationale: Insufficient documentation clearly defining the indication and therapeutic duration for antiplatelet agents carries potential risks for bleeding and/or ischemia. This was observed in patients who were veterans and was felt to represent a modifiable quality gap.

Project Summary: A 2-phase quality improvement initiative at the New Mexico Veterans Affairs Health Care System reviewed documentation among 1,100 veterans prescribed a P2Y12 inhibitor. In a randomly selected sample of 135 patients, 27% lacked documentation clearly defining therapeutic duration, and 8.4% continued P2Y12 inhibitor beyond the intended stop date. A structured electronic health record document and automated reminders were developed using a Plan-Do-Study-Act framework to address these concerns.

Take-Home Message: Structured electronic health record documentation with automated reminders can improve antiplatelet stewardship and safety.

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Cite

BibTeXRIS
BibTeX
@article{singh2026tailoring,
  title = {{Tailoring Antiplatelet Adherence}},
  author = {Rudra Pratap Singh and Breandan Kelly and Seerat Sachdeva and Stephanie Rosenberg and Harmon R. Cannon and Linda Macdonald},
  journal = {JACC Case Reports},
  year = {2026},
  month = sep,
  doi = {10.1016/j.jaccas.2026.109457},
  url = {https://doi.org/10.1016/j.jaccas.2026.109457},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Tailoring Antiplatelet Adherence
AU  - Rudra Pratap Singh
AU  - Breandan Kelly
AU  - Seerat Sachdeva
AU  - Stephanie Rosenberg
AU  - Harmon R. Cannon
AU  - Linda Macdonald
PY  - 2026
DA  - 2026/09/16
JO  - JACC Case Reports
DO  - 10.1016/j.jaccas.2026.109457
UR  - https://doi.org/10.1016/j.jaccas.2026.109457
AB  - Background: The use of P2Y12 inhibitor is highly variable, and administration is frequently confounded by inconsistent documentation that heightens risks for mismanagement, particularly following transitions of care.  Project Rationale: Insufficient documentation clearly defining the indication and therapeutic duration for antiplatelet agents carries potential risks for bleeding and/or ischemia. This was observed in patients who were veterans and was felt to represent a modifiable quality gap.  Project Summary: A 2-phase quality improvement initiative at the New Mexico Veterans Affairs Health Care System reviewed documentation among 1,100 veterans prescribed a P2Y12 inhibitor. In a randomly selected sample of 135 patients, 27% lacked documentation clearly defining therapeutic duration, and 8.4% continued P2Y12 inhibitor beyond the intended stop date. A structured electronic health record document and automated reminders were developed using a Plan-Do-Study-Act framework to address these concerns.  Take-Home Message: Structured electronic health record documentation with automated reminders can improve antiplatelet stewardship and safety.
SN  - 2666-0849
ER  -