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Peer-reviewedCC BYDiagnostics (Basel, Switzerland)

Association Between Vertical Skeletal Pattern and Mandibular Cortical Morphology: A CBCT-Based Radiomorphometric Study.

  1. 1Department of Orthodontics, Faculty of Dentistry, Istanbul Health and Technology University, Istanbul 34180, Türkiye.
  2. 2Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Istanbul Health and Technology University, Istanbul 34180, Türkiye.

Abstract

Background/Objectives: Mandibular cortical morphology has been associated with vertical facial patterns, but differences in standardized radiomorphometric indices remain unclear. This study compared five mandibular indices among vertical skeletal patterns using CBCT-derived panoramic reconstructions. Methods: This retrospective cross-sectional study included 181 adults classified as hypodivergent (n = 42), normodivergent (n = 67), or hyperdivergent (n = 72) according to the sella-nasion-to-mandibular-plane angle. Mental (MI), panoramic mandibular (PMI), gonial (GI), antegonial (AI), and mandibular cortical (MCI) indices were assessed by a blinded dentomaxillofacial radiologist, and bilateral measurements were averaged. Continuous indices were compared using ANOVA or Welch ANOVA and ANCOVA adjusted for age and sex, and the MCI using the chi-square test and logistic regression. p values across the five indices were corrected using the Holm method. Results: No index differed significantly among the groups after correction for multiple comparisons. The MI showed the most notable nominal between-group difference (hypodivergent, 3.92 ± 0.73 mm; normodivergent, 3.73 ± 0.60 mm; hyperdivergent, 3.61 ± 0.68 mm). After adjustment for age and sex, the MI was 0.35 mm greater in hypodivergent than in hyperdivergent subjects (95% CI, 0.04-0.66), but the overall group effect did not remain significant after correction (p = 0.024; Holm p = 0.118). The unadjusted association between the MCI and vertical skeletal pattern (p = 0.035) did not remain significant after correction (Holm p = 0.174) or after adjustment. The PMI, GI, and AI showed no differences. Conclusions: After correction for multiple comparisons, vertical skeletal pattern was not significantly associated with any of the five radiomorphometric indices.

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BibTeX
@article{erdem2026association,
  title = {{Association Between Vertical Skeletal Pattern and Mandibular Cortical Morphology: A CBCT-Based Radiomorphometric Study.}},
  author = {Buket Erdem and Mustafa Ozcan and Eda Didem Yalcin and Cagla Sar},
  journal = {Diagnostics (Basel, Switzerland)},
  year = {2026},
  month = sep,
  doi = {10.3390/diagnostics16193174},
  url = {https://europepmc.org/article/MED/42882330},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Association Between Vertical Skeletal Pattern and Mandibular Cortical Morphology: A CBCT-Based Radiomorphometric Study.
AU  - Buket Erdem
AU  - Mustafa Ozcan
AU  - Eda Didem Yalcin
AU  - Cagla Sar
PY  - 2026
DA  - 2026/09/30
JO  - Diagnostics (Basel, Switzerland)
DO  - 10.3390/diagnostics16193174
UR  - https://europepmc.org/article/MED/42882330
AB  - Background/Objectives: Mandibular cortical morphology has been associated with vertical facial patterns, but differences in standardized radiomorphometric indices remain unclear. This study compared five mandibular indices among vertical skeletal patterns using CBCT-derived panoramic reconstructions. Methods: This retrospective cross-sectional study included 181 adults classified as hypodivergent (n = 42), normodivergent (n = 67), or hyperdivergent (n = 72) according to the sella-nasion-to-mandibular-plane angle. Mental (MI), panoramic mandibular (PMI), gonial (GI), antegonial (AI), and mandibular cortical (MCI) indices were assessed by a blinded dentomaxillofacial radiologist, and bilateral measurements were averaged. Continuous indices were compared using ANOVA or Welch ANOVA and ANCOVA adjusted for age and sex, and the MCI using the chi-square test and logistic regression. p values across the five indices were corrected using the Holm method. Results: No index differed significantly among the groups after correction for multiple comparisons. The MI showed the most notable nominal between-group difference (hypodivergent, 3.92 ± 0.73 mm; normodivergent, 3.73 ± 0.60 mm; hyperdivergent, 3.61 ± 0.68 mm). After adjustment for age and sex, the MI was 0.35 mm greater in hypodivergent than in hyperdivergent subjects (95% CI, 0.04-0.66), but the overall group effect did not remain significant after correction (p = 0.024; Holm p = 0.118). The unadjusted association between the MCI and vertical skeletal pattern (p = 0.035) did not remain significant after correction (Holm p = 0.174) or after adjustment. The PMI, GI, and AI showed no differences. Conclusions: After correction for multiple comparisons, vertical skeletal pattern was not significantly associated with any of the five radiomorphometric indices.
SN  - 2075-4418
ER  -