Three-dimensional motion corrected free-breathing simultaneous multislice-balanced steady state free precession myocardium perfusion imaging
Abstract
Background To develop a 3D motion-corrected simultaneous multislice-balanced steady state free precession (SMS)-bSSFP acquisition to enable free-breathing myocardial perfusion with high spatial resolution and coverage. Methods A fast diaphragmatic respiratory navigator (fastNAV) module (<15 ms) was implemented into an SMS-bSSFP sequence for prospective slice-tracking. The remaining 2D in-plane motion was corrected using inline image registration. This approach (SMS-fastNAV) was compared to a reference SMS perfusion with 2D in-plane motion correction only (SMS-Ref) in 10 patients at 1.5T. Each subject underwent both perfusion protocols (six slices, resolution: 1.9 × 1.9 mm 2 ) in a random order. The residual motion of the left ventricule (LV) was assessed by measuring the average DICE coefficient of the LV (avDICE) and the average displacement of the LV center of mass location (avCOM). Subjective assessment of image quality was also performed. Results SMS-fastNAV led to lower residual LV motion than SMS-Ref before non-rigid image registration as shown by a higher avDICE (0.93±0.02 vs. 0.89±0.04, p<0.002) and decreased avCOM (2.82±0.89 mm vs. 4.23±1.29 mm, p = 0.005). After non-rigid image registration, SMS-fastNAV also led to higher avDICE score (0.95±0.01 vs. 0.94±0.02, p<0.027) and tended to decrease avCOM (0.97±0.21 mm vs. 1.01±0.25 mm, p = 0.23) with respect to SMS-Ref, suggesting a reduction in through-plane motion. There were no statistical significant differences between both approaches in terms of image quality (SMS-fastNAV: 1.79±0.50 vs. SMS-Ref: 2.00±0.59, p = 0.172). Conclusion A 3D motion correction strategy was successfully developed for free-breathing SMS-bSSFP perfusion with high spatial coverage and resolution and provides improved motion correction with respect to standard in-plane image registration only.
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BibTeX
@article{adam2026threedimensional,
title = {{Three-dimensional motion corrected free-breathing simultaneous multislice-balanced steady state free precession myocardium perfusion imaging}},
author = {Naledi Adam and Ronald Mooiweer and Andrew Tyler and Karl Kunze and Radhouene Neji and Peter Speier and Daniel Stäb and John Ng and Shino Kuriakose and Reza Razavi and Muhummad Sohaib Nazir and Amedeo Chiribiri and Sébastien Roujol},
journal = {Journal of Cardiovascular Magnetic Resonance},
year = {2026},
month = oct,
doi = {10.1016/j.jocmr.2025.101897},
url = {https://hal.science/hal-05795980v1},
note = {CC BY},
}
RIS
TY - JOUR
TI - Three-dimensional motion corrected free-breathing simultaneous multislice-balanced steady state free precession myocardium perfusion imaging
AU - Naledi Adam
AU - Ronald Mooiweer
AU - Andrew Tyler
AU - Karl Kunze
AU - Radhouene Neji
AU - Peter Speier
AU - Daniel Stäb
AU - John Ng
AU - Shino Kuriakose
AU - Reza Razavi
AU - Muhummad Sohaib Nazir
AU - Amedeo Chiribiri
AU - Sébastien Roujol
PY - 2026
DA - 2026/10/12
JO - Journal of Cardiovascular Magnetic Resonance
DO - 10.1016/j.jocmr.2025.101897
UR - https://hal.science/hal-05795980v1
AB - Background To develop a 3D motion-corrected simultaneous multislice-balanced steady state free precession (SMS)-bSSFP acquisition to enable free-breathing myocardial perfusion with high spatial resolution and coverage. Methods A fast diaphragmatic respiratory navigator (fastNAV) module (<15 ms) was implemented into an SMS-bSSFP sequence for prospective slice-tracking. The remaining 2D in-plane motion was corrected using inline image registration. This approach (SMS-fastNAV) was compared to a reference SMS perfusion with 2D in-plane motion correction only (SMS-Ref) in 10 patients at 1.5T. Each subject underwent both perfusion protocols (six slices, resolution: 1.9 × 1.9 mm 2 ) in a random order. The residual motion of the left ventricule (LV) was assessed by measuring the average DICE coefficient of the LV (avDICE) and the average displacement of the LV center of mass location (avCOM). Subjective assessment of image quality was also performed. Results SMS-fastNAV led to lower residual LV motion than SMS-Ref before non-rigid image registration as shown by a higher avDICE (0.93±0.02 vs. 0.89±0.04, p<0.002) and decreased avCOM (2.82±0.89 mm vs. 4.23±1.29 mm, p = 0.005). After non-rigid image registration, SMS-fastNAV also led to higher avDICE score (0.95±0.01 vs. 0.94±0.02, p<0.027) and tended to decrease avCOM (0.97±0.21 mm vs. 1.01±0.25 mm, p = 0.23) with respect to SMS-Ref, suggesting a reduction in through-plane motion. There were no statistical significant differences between both approaches in terms of image quality (SMS-fastNAV: 1.79±0.50 vs. SMS-Ref: 2.00±0.59, p = 0.172). Conclusion A 3D motion correction strategy was successfully developed for free-breathing SMS-bSSFP perfusion with high spatial coverage and resolution and provides improved motion correction with respect to standard in-plane image registration only.
SN - 1097-6647
SN - 1532-429X
ER -