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Peer-reviewedCC BY-NCAmerican heart journal plus : cardiology research and practice

Latest findings on complications following trans- catheter aortic valve replacement: A literature review.

  • Masoud Rezaei1,2
  • Davood Hekmatpou2,3
  • Mohammad Abbasi4
  • Ahmad Reza Baghernezhad5
  • Niloofar Ahmadi6
6 affiliations
  1. 1Department of Medical and Surgical Nursing, School of Nursing, Arak University of Medical Sciences, Arak, Iran.
  2. 2Traditional and Complementary Medicine Research Center, Arak University of Medical Sciences, Arak, Iran.
  3. 3School of Nursing, Arak University of Medical Sciences, Arak, Iran.
  4. 4Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.
  5. 5Department of Nursing, Khomein University of Medical Sciences, Khomein, Iran.
  6. 6Faculty of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.
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Abstract

Background

Severe aortic stenosis (As) is the most common valvular heart disease in developed countries, and transcatheter aortic valve replacement (TAVR) has expanded across surgical risk groups. However, procedure-related complications remain clinically important, and their reported incidence and management have evolved with newer-generation devices and techniques. This review summarizes major TAVR complications, including their incidence and pathophysiology, risk factors, clinical impact, prevention and management, and outlines remaining knowledge gaps.Materials and methods

A structured narrative review of PubMed/MEDLINE, Scopus, and Web of Science was conducted for studies published between 2012 and 2026, including randomized trials, registries, cohort studies, and systematic reviews.Results

Major complications reviewed included Stroke, Delirium, Conduction disturbances (CD) and Arrhythmias, Bleeding/Vascular(access) site injuries/Paravalvular leak (PVL), Acute Kidney Injury (AKI), Structural valve degeneration and thrombosis, Infective Endocarditis (IE) and Coronary Obstruction (CO).Conclusions

TAVR complications remain multifactorial, and their incidence and management continue to shift with device evolution and procedural experience. Optimized patient selection, procedural refinement, frailty assessment, and individualized antithrombotic strategies remain important areas for improving outcomes.

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Cite

BibTeXRIS
BibTeX
@article{rezaei2026latest,
  title = {{Latest findings on complications following trans- catheter aortic valve replacement: A literature review.}},
  author = {Masoud Rezaei and Davood Hekmatpou and Mohammad Abbasi and Ahmad Reza Baghernezhad and Niloofar Ahmadi},
  journal = {American heart journal plus : cardiology research and practice},
  year = {2026},
  month = oct,
  doi = {10.1016/j.ahjo.2026.100964},
  url = {https://europepmc.org/article/MED/42927049},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Latest findings on complications following trans- catheter aortic valve replacement: A literature review.
AU  - Masoud Rezaei
AU  - Davood Hekmatpou
AU  - Mohammad Abbasi
AU  - Ahmad Reza Baghernezhad
AU  - Niloofar Ahmadi
PY  - 2026
DA  - 2026/10/15
JO  - American heart journal plus : cardiology research and practice
DO  - 10.1016/j.ahjo.2026.100964
UR  - https://europepmc.org/article/MED/42927049
AB  - Background  Severe aortic stenosis (As) is the most common valvular heart disease in developed countries, and transcatheter aortic valve replacement (TAVR) has expanded across surgical risk groups. However, procedure-related complications remain clinically important, and their reported incidence and management have evolved with newer-generation devices and techniques. This review summarizes major TAVR complications, including their incidence and pathophysiology, risk factors, clinical impact, prevention and management, and outlines remaining knowledge gaps.Materials and methods  A structured narrative review of PubMed/MEDLINE, Scopus, and Web of Science was conducted for studies published between 2012 and 2026, including randomized trials, registries, cohort studies, and systematic reviews.Results  Major complications reviewed included Stroke, Delirium, Conduction disturbances (CD) and Arrhythmias, Bleeding/Vascular(access) site injuries/Paravalvular leak (PVL), Acute Kidney Injury (AKI), Structural valve degeneration and thrombosis, Infective Endocarditis (IE) and Coronary Obstruction (CO).Conclusions  TAVR complications remain multifactorial, and their incidence and management continue to shift with device evolution and procedural experience. Optimized patient selection, procedural refinement, frailty assessment, and individualized antithrombotic strategies remain important areas for improving outcomes.
SN  - 2666-6022
ER  -