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Peer-reviewedCC BY 4.0Frontiers in Cardiovascular Medicine

Scoring balloon versus plain balloon vessel preparation before drug-coated balloon angioplasty for femoropopliteal atherosclerotic occlusive disease: a two-centre retrospective cohort study

  • Lei Qi1,2
  • Hongzhi Sun3
  • Yaying Wu4
  • Yihao Wang2,5
  • Jiannan Wang2
  • Yizhan Shi1,2
  • Zhijian Dai1,2
  • Jiahe Zhang1,2
  • Shuangshuang Li2
  • Zan Zeng2
  • Jian Zhou2
5 affiliations
  1. 1Oriental Pan-Vascular Devices Innovation College, University of Shanghai for Science and Technology
  2. 2Department of Vascular Surgery, The Third Affiliated Hospital of Naval Medical University
  3. 3Department of Interventional Vascular, The Third People’s Hospital of Hefei (Hefei Third Clinical College of Anhui Medical University)
  4. 4Department of Vascular Surgery, Taicang TCM Hospital Affiliated to Nanjing University of Chinese Medicine (Taicang Hospital of Traditional Chinese Medicine)
  5. 5Department of Vascular Surgery and Intervention, The Fourth Affiliated Hospital of Soochow University
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Abstract

Background: Optimal vessel preparation before drug-coated balloon (DCB) angioplasty in femoropopliteal atherosclerotic occlusive disease remains counteracted by dissection and recoil. We evaluated whether scoring balloon (SB) vessel preparation improves procedural immediate effect and mid-term outcomes compared with plain balloon (PB).

Methods: Patients with femoropopliteal occlusive disease undergoing DCB angioplasty following SB or PB preparation (2022-2025) across two tertiary centers were reviewed. 1:1 propensity score matching (PSM) was implemented. Primary endpoint was target vessel dissection. Secondary endpoints included bailout stenting, procedural complications, ankle-brachial index (ABI), 12-month primary patency, and freedom from clinically driven target vessel revascularisation (CD-TVR).

Results: After matching, 63 patients were in each group. Target vessel dissection occurred in 49.2% of Group PB and 17.5% of Group SB (OR: 5.00, 95% CI: 1.91–13.06, p = 0.001). For Groups PB and SB, bailout stenting rates were 31.7% and 9.5%, respectively (OR: 3.80, 95% CI: 1.42–10.17; p = 0.008). Procedural complication rates were 6.3% and 3.2% (OR: 2.00, 95% CI: 0.37–10.92; p = 0.424). 12-month primary patency were 87.3% and 88.9% (HR: 1.18, 95% CI: 0.44–3.22; p = 0.739). 12-month freedom from CD-TVR were 88.9% and 93.7% (HR: 1.83, 95% CI: 0.52–6.47; p = 0.348).

Conclusion: In this propensity-matched cohort, SB vessel preparation before DCB angioplasty was associated with lower rates of target vessel dissection and bailout stenting than PB. No statistically significant difference in the prespecified procedural complications, 12-month patency or CD-TVR was observed.

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Cite

BibTeXRIS
BibTeX
@article{qi2026scoring,
  title = {{Scoring balloon versus plain balloon vessel preparation before drug-coated balloon angioplasty for femoropopliteal atherosclerotic occlusive disease: a two-centre retrospective cohort study}},
  author = {Lei Qi and Hongzhi Sun and Yaying Wu and Yihao Wang and Jiannan Wang and Yizhan Shi and Zhijian Dai and Jiahe Zhang and Shuangshuang Li and Zan Zeng and Jian Zhou},
  journal = {Frontiers in Cardiovascular Medicine},
  year = {2026},
  month = oct,
  doi = {10.3389/fcvm.2026.1975976},
  url = {https://www.frontiersin.org/articles/10.3389/fcvm.2026.1975976/full},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Scoring balloon versus plain balloon vessel preparation before drug-coated balloon angioplasty for femoropopliteal atherosclerotic occlusive disease: a two-centre retrospective cohort study
AU  - Lei Qi
AU  - Hongzhi Sun
AU  - Yaying Wu
AU  - Yihao Wang
AU  - Jiannan Wang
AU  - Yizhan Shi
AU  - Zhijian Dai
AU  - Jiahe Zhang
AU  - Shuangshuang Li
AU  - Zan Zeng
AU  - Jian Zhou
PY  - 2026
DA  - 2026/10/14
JO  - Frontiers in Cardiovascular Medicine
DO  - 10.3389/fcvm.2026.1975976
UR  - https://www.frontiersin.org/articles/10.3389/fcvm.2026.1975976/full
AB  - Background: Optimal vessel preparation before drug-coated balloon (DCB) angioplasty in femoropopliteal atherosclerotic occlusive disease remains counteracted by dissection and recoil. We evaluated whether scoring balloon (SB) vessel preparation improves procedural immediate effect and mid-term outcomes compared with plain balloon (PB).  Methods: Patients with femoropopliteal occlusive disease undergoing DCB angioplasty following SB or PB preparation (2022-2025) across two tertiary centers were reviewed. 1:1 propensity score matching (PSM) was implemented. Primary endpoint was target vessel dissection. Secondary endpoints included bailout stenting, procedural complications, ankle-brachial index (ABI), 12-month primary patency, and freedom from clinically driven target vessel revascularisation (CD-TVR).  Results: After matching, 63 patients were in each group. Target vessel dissection occurred in 49.2% of Group PB and 17.5% of Group SB (OR: 5.00, 95% CI: 1.91–13.06, p = 0.001). For Groups PB and SB, bailout stenting rates were 31.7% and 9.5%, respectively (OR: 3.80, 95% CI: 1.42–10.17; p = 0.008). Procedural complication rates were 6.3% and 3.2% (OR: 2.00, 95% CI: 0.37–10.92; p = 0.424). 12-month primary patency were 87.3% and 88.9% (HR: 1.18, 95% CI: 0.44–3.22; p = 0.739). 12-month freedom from CD-TVR were 88.9% and 93.7% (HR: 1.83, 95% CI: 0.52–6.47; p = 0.348).  Conclusion: In this propensity-matched cohort, SB vessel preparation before DCB angioplasty was associated with lower rates of target vessel dissection and bailout stenting than PB. No statistically significant difference in the prespecified procedural complications, 12-month patency or CD-TVR was observed.
SN  - 2297-055X
ER  -