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Peer-reviewedLicence not statedNature Metabolism

Human whole-blood NAD+ levels do not vary with age or lifestyle interventions

20 more authors
23 affiliations
  1. 1Amsterdam Gastroenterology, Endocrinology, Metabolism, Amsterdam, The Netherlands
  2. 2Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
  3. 3Core Facility Metabolomics, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
  4. 4Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands
  5. 5Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain
  6. 6Preclinical Research of Bioactive Compounds and Drugs (PREBIOF), Izpisúa Lab HiTech, Faculty of Health Sciences, Universidad Católica de Murcia (UCAM), Campus los Jerónimos, Murcia, Spain
  7. 7Laboratory Genetic Metabolic Diseases, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
  8. 8Chemistry and Pharmaceutical Sciences Department, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit (VU) Amsterdam, Amsterdam, the Netherlands
  9. 9Department of Cardiology, Amsterdam UMC, University of Amsterdam. Amsterdam Movement Sciences Institute, Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands
  10. 10Department of Nutrition and Dietetics, Faculty of Health, Sport and Physical Activity, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands
  11. 11Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland
  12. 12Biocenter Oulu, Faculty of Medicine, University of Oulu, Oulu, Finland
  13. 13Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
  14. 14Research Unit for Biomedicine and Internal Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland
  15. 15Section of Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands
  16. 16Group of Metabolism and Gene Regulation, UCAM HiTech Sport & Health Innovation Hub, Universidad Católica de Murcia, Guadalupe de Maciascoque, Murcia, Spain
  17. 17Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia
  18. 18Amsterdam Gastroenterology, Endocrinology, Metabolism, Amsterdam, The Netherlands. [email protected]
  19. 19Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. [email protected]
  20. 20Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands. [email protected]
  21. 21Amsterdam Gastroenterology, Endocrinology, Metabolism, Amsterdam, The Netherlands. [email protected]
  22. 22Emma Center for Personalized Medicine, Amsterdam UMC, Amsterdam, The Netherlands. [email protected]
  23. 23Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. [email protected]

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BibTeX
@article{tretowicz2026human,
  title = {{Human whole-blood NAD+ levels do not vary with age or lifestyle interventions}},
  author = {Maria M. Trętowicz and Angelique M. L. Scantlebery and Bauke V. Schomakers and Kaan D. Eroğlu and Michel van Weeghel and Vera Spek and Kasper Tore Vinten and Luc Legon and Evrim Coşkun and Fernando Millán-Domingo and Gloria Olaso González and Maria Carmen Gomez-Cabrera and Silvia Montoro‐García and Clara Noguera-Navarro and André B. P. Kuilenburg and Sofia Moco and Juliette C. van Hattum and Harald Thune Jorstad and Mohammed Benali and Jantine van den Helder and Esmée J.M. Biersteker and Maheswary Muniandy and Kirsi Hannele Pietiläinen and Eija Pirinen and P. Eline Slagboom and Marian Beekman and Joris Deelen and Ruben Zapata Perez and Peter J.M. Weijs and Michael Tieland and Georges E. Janssens and Riekelt H. Houtkooper},
  journal = {Nature Metabolism},
  year = {2026},
  month = may,
  doi = {10.1038/s42255-026-01537-5},
  url = {https://pure.amsterdamumc.nl/en/publications/d07ebdbb-5ae3-4c68-bb01-193d969cbf4f},
}
RIS
TY  - JOUR
TI  - Human whole-blood NAD+ levels do not vary with age or lifestyle interventions
AU  - Maria M. Trętowicz
AU  - Angelique M. L. Scantlebery
AU  - Bauke V. Schomakers
AU  - Kaan D. Eroğlu
AU  - Michel van Weeghel
AU  - Vera Spek
AU  - Kasper Tore Vinten
AU  - Luc Legon
AU  - Evrim Coşkun
AU  - Fernando Millán-Domingo
AU  - Gloria Olaso González
AU  - Maria Carmen Gomez-Cabrera
AU  - Silvia Montoro‐García
AU  - Clara Noguera-Navarro
AU  - André B. P. Kuilenburg
AU  - Sofia Moco
AU  - Juliette C. van Hattum
AU  - Harald Thune Jorstad
AU  - Mohammed Benali
AU  - Jantine van den Helder
AU  - Esmée J.M. Biersteker
AU  - Maheswary Muniandy
AU  - Kirsi Hannele Pietiläinen
AU  - Eija Pirinen
AU  - P. Eline Slagboom
AU  - Marian Beekman
AU  - Joris Deelen
AU  - Ruben Zapata Perez
AU  - Peter J.M. Weijs
AU  - Michael Tieland
AU  - Georges E. Janssens
AU  - Riekelt H. Houtkooper
PY  - 2026
DA  - 2026/05/14
JO  - Nature Metabolism
DO  - 10.1038/s42255-026-01537-5
UR  - https://pure.amsterdamumc.nl/en/publications/d07ebdbb-5ae3-4c68-bb01-193d969cbf4f
SN  - 2522-5812
ER  -