Skip to content
DraconiticResearch
Search Sources API
203,203 studies31 sourcesUpdated 11 min ago
Peer-reviewedCC BY-NC-NDThe Saudi dental journal

Performance of large language models in providing patient- oriented information on gingival recession: a comparative study.

  1. 1Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, 12372, Saudi Arabia. [email protected].

Abstract

Patients are increasingly turning to large language models (LLMs) for health information, but the quality of patient-oriented information remains uncertain. This article evaluated the performance of three major LLMs in answering clinically relevant patient's questions related to gingival recession. A descriptive comparative study was carried out utilizing twenty standardized patient-centered questions related to gingival recession. Each question was submitted once to ChatGPT 5.5, Gemini 3.5, and Claude Sonnet 5, generating 60 responses. Five board-certified periodontists independently evaluated the responses using the validated Accuracy of Information (AOI) Index, a completeness scale, and expert preference rankings. Word count and response generation time were also recorded. Non-parametric tests and generalized estimating equations (GEE) were applied for statistical analysis, with statistical significance set at p ≤ 0.05. No significant differences were found among the three LLMs in accuracy (p = 0.993) or completeness (p = 0.972). ChatGPT generated responses significantly faster (median: 5.82 s) and with fewer words (median: 232) than Gemini (8.46 s; 438 words) and Claude (14.61 s; 333.5 words) (both p < 0.001). Expert preference rankings differed significantly (p = 0.002): Gemini and Claude were each ranked first in 38% of evaluations, compared with 24% for ChatGPT. For all three models, the highest accuracy was observed in Post-treatment Care. The three LLMs offered broadly comparable levels of accuracy and completeness when answering patient-oriented questions with respect to gingival recession. ChatGPT was faster and more concise, while Gemini and Claude were more often preferred by the expert evaluators. These LLMs may be useful as adjuncts to patient education, but they should complement rather than replace professional periodontal consultation.

Related

  1. Performance of large language models in prescription review: a comparative study
    Can Huang, Yanfang Sun, Wei Liu
    Frontiers in medicinePeer-reviewedCC BYFull textGeneral medicineEurope PMC
  2. Quality, Readability, and Content Deficiencies of Three Large Language Models in Bee Sting Health Information: A Comparative Evaluation with Patient Perspectives
    R. Xu, L. Yang, X. Zhang +3
    medRxivPreprintCC BYFull textEpidemiology & public healthmedRxiv
  3. Quality, readability, and information fidelity of large language model–generated versus physician-authored informed-consent content for targeted therapies: a blinded, paired comparative study
    Yue Xie, Yuan Gao, Jiajing Peng +6
    Frontiers in PharmacologyPeer-reviewedCC BY 4.0Pharmacology & toxicologyFrontiersCrossref
  4. Large language models as sources of diabetic retinopathy patient education: a comparative evaluation of safety, health information quality, and readability
    Zhiqi Chen, Wen Liu, Jing Zhang +6
    Frontiers in public healthPeer-reviewedCC BYFull textEpidemiology & public healthEurope PMCCrossref
  5. Benchmarking the performance of large language models on medical genetics questions: a comparative evaluation of GPT-5.1, Gemini Pro 3, and Claude Opus 4.5.
    Muserref Basdemirci, Melek Tassoker
    Frontiers in medicinePeer-reviewedCC BYFull text1 citedEpidemiology & public healthEurope PMCPMC
BibTeX
@article{albeshri2026performance,
  title = {{Performance of large language models in providing patient- oriented information on gingival recession: a comparative study.}},
  author = {Sultan Albeshri},
  journal = {The Saudi dental journal},
  year = {2026},
  month = oct,
  doi = {10.1007/s44445-026-00247-8},
  url = {https://europepmc.org/article/MED/42895602},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Performance of large language models in providing patient- oriented information on gingival recession: a comparative study.
AU  - Sultan Albeshri
PY  - 2026
DA  - 2026/10/19
JO  - The Saudi dental journal
DO  - 10.1007/s44445-026-00247-8
UR  - https://europepmc.org/article/MED/42895602
AB  - Patients are increasingly turning to large language models (LLMs) for health information, but the quality of patient-oriented information remains uncertain. This article evaluated the performance of three major LLMs in answering clinically relevant patient's questions related to gingival recession. A descriptive comparative study was carried out utilizing twenty standardized patient-centered questions related to gingival recession. Each question was submitted once to ChatGPT 5.5, Gemini 3.5, and Claude Sonnet 5, generating 60 responses. Five board-certified periodontists independently evaluated the responses using the validated Accuracy of Information (AOI) Index, a completeness scale, and expert preference rankings. Word count and response generation time were also recorded. Non-parametric tests and generalized estimating equations (GEE) were applied for statistical analysis, with statistical significance set at p ≤ 0.05. No significant differences were found among the three LLMs in accuracy (p = 0.993) or completeness (p = 0.972). ChatGPT generated responses significantly faster (median: 5.82 s) and with fewer words (median: 232) than Gemini (8.46 s; 438 words) and Claude (14.61 s; 333.5 words) (both p < 0.001). Expert preference rankings differed significantly (p = 0.002): Gemini and Claude were each ranked first in 38% of evaluations, compared with 24% for ChatGPT. For all three models, the highest accuracy was observed in Post-treatment Care. The three LLMs offered broadly comparable levels of accuracy and completeness when answering patient-oriented questions with respect to gingival recession. ChatGPT was faster and more concise, while Gemini and Claude were more often preferred by the expert evaluators. These LLMs may be useful as adjuncts to patient education, but they should complement rather than replace professional periodontal consultation.
SN  - 1013-9052
SN  - 1658-3558
SN  - 2524-1702
ER  -