An Endoscopic Ultrasound-guided Fine-needle Biopsy as a Diagnostic Tool for Isolated Hepatic Sarcoidosis
Abstract
A 72-year-old man was referred for the evaluation of multiple hepatic lesions incidentally detected on contrast-enhanced computed tomography during prostate cancer staging. Imaging could not exclude malignancy, but the tumor markers were within the normal limits, except for prostate-specific antigen, and endoscopic examinations revealed no primary malignancy. A percutaneous biopsy was not feasible because of the lesion size and location. Endoscopic ultrasound (EUS) revealed a 25-mm caudate lobe lesion, from which fine-needle biopsy (FNB) was performed without complications. A histopathological examination confirmed a diagnosis of hepatic sarcoidosis. This case highlights the utility of EUS-FNB for the diagnosis of hepatic sarcoidosis, especially when a conventional biopsy is impractical.
Related
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BibTeX
@article{honda2026endoscopic,
title = {{An Endoscopic Ultrasound-guided Fine-needle Biopsy as a Diagnostic Tool for Isolated Hepatic Sarcoidosis}},
author = {Hideho Honda and Hiroto Tanoue and Haruka Goda and Yuya Komoto and Tomohisa Nakaya and Yasuhiko Gotoh and Koichi Kagawa and Kazuhiro Mizukami},
journal = {Internal Medicine},
year = {2026},
month = aug,
doi = {10.2169/internalmedicine.6666-25},
url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/16/65_6666-25/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - An Endoscopic Ultrasound-guided Fine-needle Biopsy as a Diagnostic Tool for Isolated Hepatic Sarcoidosis
AU - Hideho Honda
AU - Hiroto Tanoue
AU - Haruka Goda
AU - Yuya Komoto
AU - Tomohisa Nakaya
AU - Yasuhiko Gotoh
AU - Koichi Kagawa
AU - Kazuhiro Mizukami
PY - 2026
DA - 2026/08/15
JO - Internal Medicine
DO - 10.2169/internalmedicine.6666-25
UR - https://www.jstage.jst.go.jp/article/internalmedicine/65/16/65_6666-25/_article
AB - A 72-year-old man was referred for the evaluation of multiple hepatic lesions incidentally detected on contrast-enhanced computed tomography during prostate cancer staging. Imaging could not exclude malignancy, but the tumor markers were within the normal limits, except for prostate-specific antigen, and endoscopic examinations revealed no primary malignancy. A percutaneous biopsy was not feasible because of the lesion size and location. Endoscopic ultrasound (EUS) revealed a 25-mm caudate lobe lesion, from which fine-needle biopsy (FNB) was performed without complications. A histopathological examination confirmed a diagnosis of hepatic sarcoidosis. This case highlights the utility of EUS-FNB for the diagnosis of hepatic sarcoidosis, especially when a conventional biopsy is impractical.
SN - 1349-7235
SN - 0918-2918
ER -