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Peer-reviewedCC BY-NCOman Medical Journal

Subacute Thyroiditis Following Third Dose of Pfizer-BioNTech COVID-19 (mRNA) Vaccine in a Patient with Clear Cell Renal Cell Carcinoma: A Case Report

  1. 1Division of Nephrology, Department of Medicine, Sultan Qaboos Comprehensive Cancer Care, Muscat, Oman
  2. 2Department of Medical Oncology, Sultan Qaboos Comprehensive Cancer Care, Muscat, Oman
  3. 3Department of Pharmacy, Sultan Qaboos Comprehensive Cancer Care, Muscat, Oman

Abstract

Over 160 cases of subacute thyroiditis (SAT) following COVID-19 vaccination or infection have been reported in the literature. Roughly one-half were attributed to either the first or second dose of the COVID-19 vaccine. We report a rare case of SAT in a 47-year-old male patient with a history of clear cell renal cell carcinoma and advanced chronic kidney disease, among other comorbidities, excluding thyroid disease. After he received the third dose of the Pfizer mRNA vaccine, a deranged thyroid profile was accidentally discovered. His SAT remained asymptomatic and normalized in about six months without treatment. SAT post-COVID vaccination is a self-limiting and rare condition that should be considered in the differential diagnosis of silent thyroiditis.

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BibTeX
@article{nagy2026subacute,
  title = {{Subacute Thyroiditis Following Third Dose of Pfizer-BioNTech COVID-19 (mRNA) Vaccine in a Patient with Clear Cell Renal Cell Carcinoma: A Case Report}},
  author = {Amro Nagy and Muhammad Yaqut and Doaa Abbas and Amna Mohamed},
  journal = {Oman Medical Journal},
  year = {2026},
  month = jul,
  doi = {10.5001/omj.2026.10},
  url = {https://doi.org/10.5001/omj.2026.10},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Subacute Thyroiditis Following Third Dose of Pfizer-BioNTech COVID-19 (mRNA) Vaccine in a Patient with Clear Cell Renal Cell Carcinoma: A Case Report
AU  - Amro Nagy
AU  - Muhammad Yaqut
AU  - Doaa Abbas
AU  - Amna Mohamed
PY  - 2026
DA  - 2026/07/01
JO  - Oman Medical Journal
DO  - 10.5001/omj.2026.10
UR  - https://doi.org/10.5001/omj.2026.10
AB  - Over 160 cases of subacute thyroiditis (SAT) following COVID-19 vaccination or infection have been reported in the literature. Roughly one-half were attributed to either the first or second dose of the COVID-19 vaccine. We report a rare case of SAT in a 47-year-old male patient with a history of clear cell renal cell carcinoma and advanced chronic kidney disease, among other comorbidities, excluding thyroid disease. After he received the third dose of the Pfizer mRNA vaccine, a deranged thyroid profile was accidentally discovered. His SAT remained asymptomatic and normalized in about six months without treatment. SAT post-COVID vaccination is a self-limiting and rare condition that should be considered in the differential diagnosis of silent thyroiditis.
SN  - 1999-768X
SN  - 2070-5204
ER  -