Cardiometabolic diseases and prescription patterns in a Kuwait tertiary-care hospital: A retrospective cross-sectional chart review.
4 affiliations
- 1Department of Medicine, College of Medicine and Health Sciences, Abdullah Al Salem University, Kuwait.
- 2Division of Gastroenterology, Department of Internal Medicine, Mubarak AlKabeer University Hospital, Kuwait.
- 3School of Medicine, Royal College of Surgeons in Ireland, Medical University of Bahrain, Kingdom of Bahrain.
- 4Department of Community Medicine and Behavioral Sciences, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Abstract
Background
Tertiary-care data can provide critical insights into clinical demographics in Gulf Arab settings where these data remain limited, despite reflecting hospital-based frequencies rather than population-level prevalence. This study aimed to descriptively characterize cardiometabolic disease and medication frequencies in a tertiary-care cohort.Methods
This retrospective cross-sectional chart review included adult patients with ≥1 ICD-10-coded chronic cardiometabolic condition at Mubarak Hospital, Kuwait, between January 1, 2022, and December 31, 2024. Disease and medication frequencies were summarized by age group (<35 years, 35 to < 65 years, and ≥65 years) and sex. Univariate and multivariate associations were evaluated. Binomial regression models estimated adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs), adjusting for age or sex, nationality, and smoking status, with further adjustment for ischemic heart disease (IHD) in selected models.Results
Among 501 patients (54.1% female; mean age 63.7 ± 14.6 years), the most frequent conditions were hypertension (77.8%), diabetes mellitus (58.5%), dyslipidemia (44.7%), and IHD (23.6%). Lipid-lowering medications (76.05%) and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (59.5%) were the most common medications. Disease frequencies increased significantly with age. Compared with those aged 35 to <65 years, patients aged ≥65 years had higher adjusted prevalences of type 2 diabetes (aPR: 1.17, 95% CI: 1.00-1.35), hypertension (aPR: 1.18, 95% CI: 1.07-1.30), and IHD (aPR: 2.37, 95% CI: 1.68-3.35). Males had a significantly higher adjusted prevalence of chronic kidney disease (aPR: 1.96, 95% CI: 1.20-3.19) and IHD (aPR: 1.69, 95% CI: 1.22-2.32) than females. Notably, the higher prevalence of aspirin/clopidogrel antiplatelet therapy in males (aPR: 1.37, 95% CI: 1.11-1.69) persisted even after further adjustment for IHD (aPR: 1.30, 95% CI: 1.05-1.60).Conclusion
Within this selected cohort, the cardiometabolic burden was high and varied by age and sex. Multicenter Gulf studies with patient-level adjustment are needed to characterize the disease burden and prescribing frequencies.
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BibTeX
@article{shehab2026cardiometabolic,
title = {{Cardiometabolic diseases and prescription patterns in a Kuwait tertiary-care hospital: A retrospective cross-sectional chart review.}},
author = {Mohammed Shehab and Abdulwahab AlSayegh and Hala AlOmar and Sharifa Al-Fajri and Ali H Ziyab},
journal = {Journal of Taibah University Medical Sciences},
year = {2026},
month = oct,
doi = {10.1016/j.jtumed.2026.09.009},
url = {https://europepmc.org/article/MED/42903606},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Cardiometabolic diseases and prescription patterns in a Kuwait tertiary-care hospital: A retrospective cross-sectional chart review.
AU - Mohammed Shehab
AU - Abdulwahab AlSayegh
AU - Hala AlOmar
AU - Sharifa Al-Fajri
AU - Ali H Ziyab
PY - 2026
DA - 2026/10/12
JO - Journal of Taibah University Medical Sciences
DO - 10.1016/j.jtumed.2026.09.009
UR - https://europepmc.org/article/MED/42903606
AB - Background Tertiary-care data can provide critical insights into clinical demographics in Gulf Arab settings where these data remain limited, despite reflecting hospital-based frequencies rather than population-level prevalence. This study aimed to descriptively characterize cardiometabolic disease and medication frequencies in a tertiary-care cohort.Methods This retrospective cross-sectional chart review included adult patients with ≥1 ICD-10-coded chronic cardiometabolic condition at Mubarak Hospital, Kuwait, between January 1, 2022, and December 31, 2024. Disease and medication frequencies were summarized by age group (<35 years, 35 to < 65 years, and ≥65 years) and sex. Univariate and multivariate associations were evaluated. Binomial regression models estimated adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs), adjusting for age or sex, nationality, and smoking status, with further adjustment for ischemic heart disease (IHD) in selected models.Results Among 501 patients (54.1% female; mean age 63.7 ± 14.6 years), the most frequent conditions were hypertension (77.8%), diabetes mellitus (58.5%), dyslipidemia (44.7%), and IHD (23.6%). Lipid-lowering medications (76.05%) and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (59.5%) were the most common medications. Disease frequencies increased significantly with age. Compared with those aged 35 to <65 years, patients aged ≥65 years had higher adjusted prevalences of type 2 diabetes (aPR: 1.17, 95% CI: 1.00-1.35), hypertension (aPR: 1.18, 95% CI: 1.07-1.30), and IHD (aPR: 2.37, 95% CI: 1.68-3.35). Males had a significantly higher adjusted prevalence of chronic kidney disease (aPR: 1.96, 95% CI: 1.20-3.19) and IHD (aPR: 1.69, 95% CI: 1.22-2.32) than females. Notably, the higher prevalence of aspirin/clopidogrel antiplatelet therapy in males (aPR: 1.37, 95% CI: 1.11-1.69) persisted even after further adjustment for IHD (aPR: 1.30, 95% CI: 1.05-1.60).Conclusion Within this selected cohort, the cardiometabolic burden was high and varied by age and sex. Multicenter Gulf studies with patient-level adjustment are needed to characterize the disease burden and prescribing frequencies.
SN - 1658-3612
ER -