Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 42 min ago
Peer-reviewedCC BY 4.0Infectious Diseases of Poverty

National Ebola preparedness policy architecture and health system readiness in the Democratic Republic of the Congo and Uganda: a scoping review anchored in the 2026 Bundibugyo outbreak

5 affiliations
  1. 1Institute for Development, Western Area, Freetown, Sierra Leone
  2. 2Ministry of Health, Youyi Building, Freetown, Sierra Leone
  3. 3Ministry of Health, Kampala, Uganda
  4. 4Department of Biological Sciences, School of Basic Sciences, Njala University, Private Mail Bag, Freetown, Sierra Leone
  5. 5Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia

Abstract

Background: The 2026 Bundibugyo virus disease outbreak was declared in the Democratic Republic of the Congo (DRC) on 15 May 2026, and Uganda confirmed its first case the same day. Neither country had a licensed vaccine or treatment for the virus, yet the outbreak took very different courses in the two. This scoping review maps the evidence on their national preparedness instruments and health system readiness.

Methods: We followed the Arksey and O'Malley framework, Joanna Briggs Institute guidance and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. National instruments in force at the onset, International Health Regulations evaluations and outbreak documents were sought from the issuing bodies, verified and charted against 52 component requirements in ten dimensions, with operational specificity as an eleventh. A fixed rule assigned each country a four-level descriptor per dimension, and documented outbreak risks were mapped against the gaps.

Results: We included 57 sources, 15 of them national instruments. Uganda's instruments addressed 47 of 52 components (90.4%) and the DRC's 38 (73.1%), and 31.7% of Ugandan and 15.2% of Congolese provisions were highly specific. Uganda was rated higher in six dimensions, including surveillance, isolation capacity, displaced populations and accountability, and equal in five. Both were inadequate on cross-border governance, and neither had a Bundibugyo-specific countermeasure provision. In the 2023 Joint External Evaluations the mean indicator score was 2.75 in Uganda and 1.63 in the DRC (paired difference 1.13, 95% confidence interval 0.83 to 1.42). Uganda's outbreak ended with 20 confirmed cases, whereas the DRC had reported 7890 confirmed cases by 23 September. The DRC's response plan of May 2026 was highly specific in 21 of 37 provisions.

Conclusions: The two countries differed in standing capacity and in the specificity of their standing instruments. The DRC's highly specific response plan suggests that its gap lay in standing arrangements rather than in response planning. A documentary review cannot establish that these differences caused the different courses of the outbreak. Priorities are surveillance and isolation capacity in the DRC, cross-border governance in both countries and national pathways for investigational Bundibugyo products.

Graphical Abstract:

Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s40249-026-01521-x.

Related

  1. One Health preparedness for Ebola disease caused by Bundibugyo virus: lessons from the 2026 outbreak centred in the Democratic Republic of the Congo.
    Yuxuan Shao, Jue Liu, Lei Zhou
    Science in One HealthPeer-reviewedCC BYFull textInfectious diseaseEurope PMC
  2. Reported fatality ratios and surveillance data readiness: a test applied to health zones in the 2026 Bundibugyo virus disease epidemic, Democratic Republic of the Congo
    J. G. L. Verheyden, C. N. Mudogo, W. Jacquet
    medRxivPreprintCC BY-NC-NDFull textEpidemiology & public healthmedRxiv
  3. Ebola preparedness in Sierra Leone during the 2026 Bundibugyo virus emergency: institutional findings and introduction of the Architectural and Operational Readiness Gap (AORG) framework.
    Eric Nzirakaindi Ikoona, Lucy Namulemo, Mary Magdalene Sinnah +2
    The Pan African medical journalPeer-reviewedCC BYFull textGeneral medicineEurope PMCPMC
  4. Sub-national heterogeneity in the time-varying reproduction number during the 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: a hierarchical Bayesian analysis
    J. G. L. Verheyden, C. N. Mudogo, W. Jacquet
    medRxivPreprintCC BY-NC-NDFull textEpidemiology & public healthmedRxiv
  5. Beyond viral species: the increasing mortality burden of the ongoing Bundibugyo ebolavirus outbreak in the Democratic Republic of the Congo
    Justin Kambale Kahingi, Relindis Mpembe Ngila, Roland Muhindo Muyisa
    Infectious MedicinePeer-reviewedCC BY-NC-ND 4.0Full textInfectious diseasePMC
BibTeX
@article{osborne2026national,
  title = {{National Ebola preparedness policy architecture and health system readiness in the Democratic Republic of the Congo and Uganda: a scoping review anchored in the 2026 Bundibugyo outbreak}},
  author = {Augustus Osborne and Morie Vandi and Hafsa Sentogo Lukwata and Camilla Bangura and Umar Sesay},
  journal = {Infectious Diseases of Poverty},
  year = {2026},
  month = nov,
  doi = {10.1186/s40249-026-01521-x},
  url = {https://doi.org/10.1186/s40249-026-01521-x},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - National Ebola preparedness policy architecture and health system readiness in the Democratic Republic of the Congo and Uganda: a scoping review anchored in the 2026 Bundibugyo outbreak
AU  - Augustus Osborne
AU  - Morie Vandi
AU  - Hafsa Sentogo Lukwata
AU  - Camilla Bangura
AU  - Umar Sesay
PY  - 2026
DA  - 2026/11/05
JO  - Infectious Diseases of Poverty
DO  - 10.1186/s40249-026-01521-x
UR  - https://doi.org/10.1186/s40249-026-01521-x
AB  - Background: The 2026 Bundibugyo virus disease outbreak was declared in the Democratic Republic of the Congo (DRC) on 15 May 2026, and Uganda confirmed its first case the same day. Neither country had a licensed vaccine or treatment for the virus, yet the outbreak took very different courses in the two. This scoping review maps the evidence on their national preparedness instruments and health system readiness.  Methods: We followed the Arksey and O'Malley framework, Joanna Briggs Institute guidance and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. National instruments in force at the onset, International Health Regulations evaluations and outbreak documents were sought from the issuing bodies, verified and charted against 52 component requirements in ten dimensions, with operational specificity as an eleventh. A fixed rule assigned each country a four-level descriptor per dimension, and documented outbreak risks were mapped against the gaps.  Results: We included 57 sources, 15 of them national instruments. Uganda's instruments addressed 47 of 52 components (90.4%) and the DRC's 38 (73.1%), and 31.7% of Ugandan and 15.2% of Congolese provisions were highly specific. Uganda was rated higher in six dimensions, including surveillance, isolation capacity, displaced populations and accountability, and equal in five. Both were inadequate on cross-border governance, and neither had a Bundibugyo-specific countermeasure provision. In the 2023 Joint External Evaluations the mean indicator score was 2.75 in Uganda and 1.63 in the DRC (paired difference 1.13, 95% confidence interval 0.83 to 1.42). Uganda's outbreak ended with 20 confirmed cases, whereas the DRC had reported 7890 confirmed cases by 23 September. The DRC's response plan of May 2026 was highly specific in 21 of 37 provisions.  Conclusions: The two countries differed in standing capacity and in the specificity of their standing instruments. The DRC's highly specific response plan suggests that its gap lay in standing arrangements rather than in response planning. A documentary review cannot establish that these differences caused the different courses of the outbreak. Priorities are surveillance and isolation capacity in the DRC, cross-border governance in both countries and national pathways for investigational Bundibugyo products.  Graphical Abstract:  Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s40249-026-01521-x.
SN  - 2095-5162
SN  - 2049-9957
ER  -