Auxological and pubertal outcomes of children with Kawasaki disease: Experience from Chandigarh, India
Abstract
BACKGROUND: Kawasaki disease (KD) is an acute childhood vasculitis with potential long-term cardiovascular sequelae. However, data regarding auxological and pubertal outcomes in children with KD, particularly from developing countries, remain limited.
AIM: To study physical and pubertal growth patterns in male and female children with KD. We also aimed to examine lipid profiles and their relationship with fat distribution in KD patients at higher risk for coronary abnormalities.
METHODS: The research employed a cross-sectional approach and incorporated anthropometric evaluations, puberty assessment, and analyses of lipid profiles. 47 children with KD (32 boys and 15 girls) who were over 8 years old and had been diagnosed at least 5 years prior to the study, along with 54 healthy control participants (35 boys and 19 girls) matched for age, gender, and socioeconomic background were included in this cross-sectional study.
RESULTS: Male patients with KD demonstrated significantly higher height-for-age Z-scores, while weight-for-age Z-scores and body mass index Z-scores were numerically higher compared to controls. Female patients with KD exhibited increased height-for-age Z-scores, skinfold thickness, as well as waist and hip circumferences in comparison to the control group. KD patients demonstrated normal pubertal development, with no signs of delayed or early pubertal onset. Thirteen KD subjects (27.6%) had coronary artery abnormalities.
CONCLUSION: The study’s findings have implications for the long-term follow-up and management of KD in pediatric populations, suggesting that children with KD generally demonstrate normal growth and pubertal development comparable to healthy controls.
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BibTeX
@article{thakur2026auxological,
title = {{Auxological and pubertal outcomes of children with Kawasaki disease: Experience from Chandigarh, India}},
author = {Sudip Thakur and Harvinder Kaur and Rakesh Kumar Pilania and Jayakanthan Kabeerdoss and Surjit Singh},
journal = {World Journal of Clinical Pediatrics},
year = {2026},
month = nov,
doi = {10.5409/wjcp.122376},
url = {https://doi.org/10.5409/wjcp.122376},
note = {CC BY-NC 4.0},
}
RIS
TY - JOUR
TI - Auxological and pubertal outcomes of children with Kawasaki disease: Experience from Chandigarh, India
AU - Sudip Thakur
AU - Harvinder Kaur
AU - Rakesh Kumar Pilania
AU - Jayakanthan Kabeerdoss
AU - Surjit Singh
PY - 2026
DA - 2026/11/03
JO - World Journal of Clinical Pediatrics
DO - 10.5409/wjcp.122376
UR - https://doi.org/10.5409/wjcp.122376
AB - BACKGROUND: Kawasaki disease (KD) is an acute childhood vasculitis with potential long-term cardiovascular sequelae. However, data regarding auxological and pubertal outcomes in children with KD, particularly from developing countries, remain limited. AIM: To study physical and pubertal growth patterns in male and female children with KD. We also aimed to examine lipid profiles and their relationship with fat distribution in KD patients at higher risk for coronary abnormalities. METHODS: The research employed a cross-sectional approach and incorporated anthropometric evaluations, puberty assessment, and analyses of lipid profiles. 47 children with KD (32 boys and 15 girls) who were over 8 years old and had been diagnosed at least 5 years prior to the study, along with 54 healthy control participants (35 boys and 19 girls) matched for age, gender, and socioeconomic background were included in this cross-sectional study. RESULTS: Male patients with KD demonstrated significantly higher height-for-age Z-scores, while weight-for-age Z-scores and body mass index Z-scores were numerically higher compared to controls. Female patients with KD exhibited increased height-for-age Z-scores, skinfold thickness, as well as waist and hip circumferences in comparison to the control group. KD patients demonstrated normal pubertal development, with no signs of delayed or early pubertal onset. Thirteen KD subjects (27.6%) had coronary artery abnormalities. CONCLUSION: The study’s findings have implications for the long-term follow-up and management of KD in pediatric populations, suggesting that children with KD generally demonstrate normal growth and pubertal development comparable to healthy controls.
SN - 2219-2808
ER -