Surgical management of a rare bronchial granular cell tumor: a case report
Abstract
Bronchial granular cell tumor (GCT) is exceptionally rare, accounting for only 6%–10% of all GCT cases and may be misdiagnosed because of its nonspecific clinical and radiological features. We report a 50-year-old man with a 20-day history of intermittent cough, sputum production, chest tightness, and dyspnea. Chest computed tomography revealed a 12 × 11 mm nodule in the medial segmental bronchus of the right middle lobe, resulting in incomplete lung expansion. Bronchoscopy demonstrated a polypoid mass obstructing the bronchial lumen. Histopathological examination and immunohistochemical positivity for S100, SOX10, and CD68 confirmed bronchial GCT. The patient underwent video-assisted thoracoscopic right middle lobectomy, followed by an uneventful recovery, with no recurrence at three months. This case highlights the diagnostic challenges of bronchial GCT and supports surgical resection as the preferred treatment, particularly for lesions causing substantial bronchial obstruction.
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BibTeX
@article{wang2026surgical,
title = {{Surgical management of a rare bronchial granular cell tumor: a case report}},
author = {Yilun Wang and Yaojing Zhang and Hongcan Shi},
journal = {Journal of surgical case reports},
year = {2026},
month = oct,
doi = {10.1093/jscr/rjag997},
url = {https://europepmc.org/article/PMC/PMC13722125},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Surgical management of a rare bronchial granular cell tumor: a case report
AU - Yilun Wang
AU - Yaojing Zhang
AU - Hongcan Shi
PY - 2026
DA - 2026/10/01
JO - Journal of surgical case reports
DO - 10.1093/jscr/rjag997
UR - https://europepmc.org/article/PMC/PMC13722125
AB - Bronchial granular cell tumor (GCT) is exceptionally rare, accounting for only 6%–10% of all GCT cases and may be misdiagnosed because of its nonspecific clinical and radiological features. We report a 50-year-old man with a 20-day history of intermittent cough, sputum production, chest tightness, and dyspnea. Chest computed tomography revealed a 12 × 11 mm nodule in the medial segmental bronchus of the right middle lobe, resulting in incomplete lung expansion. Bronchoscopy demonstrated a polypoid mass obstructing the bronchial lumen. Histopathological examination and immunohistochemical positivity for S100, SOX10, and CD68 confirmed bronchial GCT. The patient underwent video-assisted thoracoscopic right middle lobectomy, followed by an uneventful recovery, with no recurrence at three months. This case highlights the diagnostic challenges of bronchial GCT and supports surgical resection as the preferred treatment, particularly for lesions causing substantial bronchial obstruction.
SN - 2042-8812
ER -