Generating eukaryotic reference genome assemblies: Earth BioGenome Project quality standards and recommendations

@misc{howe2026generating,
  title = {{Generating eukaryotic reference genome assemblies: Earth BioGenome Project quality standards and recommendations}},
  author = {Kerstin Howe and Dolores R. Agius and Tyler Alioto and Jean-Marc Aury and Roberto Biello and Mark Blaxter and Matthew W. Brown and Tom Brown and Bernat Burriel-Carranza and Haoyu Cheng and Dario Copetti and Solenne Correard and Fernando Cruz and Paul Davis and Aleksandra Denisova and Giulio Formenti and Pedro A. F. Galante and Caroline Howard and Kamil S. Jaron and Erich D. Jarvis and Sergei Kliver and Sergey Koren and Ilia J. Leitch and Harris Lewin and Heng Li and Kerstin Lindblad-Toh and Jack A. Medico and Matthieu Muffato and Zemin Ning and Javan Okendo and Shujun Ou and Marc Palmada-Flores and Brendan J. Pinto and Aurora Ruiz-Herrera and Abdoallah Sharaf and Ying Sims and Jeramiah J. Smith and Marco Sollitto and Cibele G. Sotero-Caio and Marcela Uliano-Silva and Sibelle T. Vilaça and Robert M. Waterhouse and Melissa A. Wilson and Chentao Yang and Guojie Zhang and Chenxi Zhou and Yang Zhou and Richard Durbin},
  howpublished = {arXiv},
  year = {2026},
  month = oct,
  doi = {10.48550/arxiv.2610.03075},
  eprint = {2610.03075},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2610.03075},
  note = {CC BY 4.0},
}

TY  - UNPB
TI  - Generating eukaryotic reference genome assemblies: Earth BioGenome Project quality standards and recommendations
AU  - Kerstin Howe
AU  - Dolores R. Agius
AU  - Tyler Alioto
AU  - Jean-Marc Aury
AU  - Roberto Biello
AU  - Mark Blaxter
AU  - Matthew W. Brown
AU  - Tom Brown
AU  - Bernat Burriel-Carranza
AU  - Haoyu Cheng
AU  - Dario Copetti
AU  - Solenne Correard
AU  - Fernando Cruz
AU  - Paul Davis
AU  - Aleksandra Denisova
AU  - Giulio Formenti
AU  - Pedro A. F. Galante
AU  - Caroline Howard
AU  - Kamil S. Jaron
AU  - Erich D. Jarvis
AU  - Sergei Kliver
AU  - Sergey Koren
AU  - Ilia J. Leitch
AU  - Harris Lewin
AU  - Heng Li
AU  - Kerstin Lindblad-Toh
AU  - Jack A. Medico
AU  - Matthieu Muffato
AU  - Zemin Ning
AU  - Javan Okendo
AU  - Shujun Ou
AU  - Marc Palmada-Flores
AU  - Brendan J. Pinto
AU  - Aurora Ruiz-Herrera
AU  - Abdoallah Sharaf
AU  - Ying Sims
AU  - Jeramiah J. Smith
AU  - Marco Sollitto
AU  - Cibele G. Sotero-Caio
AU  - Marcela Uliano-Silva
AU  - Sibelle T. Vilaça
AU  - Robert M. Waterhouse
AU  - Melissa A. Wilson
AU  - Chentao Yang
AU  - Guojie Zhang
AU  - Chenxi Zhou
AU  - Yang Zhou
AU  - Richard Durbin
PY  - 2026
DA  - 2026/10/02
PB  - arXiv
DO  - 10.48550/arxiv.2610.03075
UR  - https://arxiv.org/abs/2610.03075
AB  - Reference genome assemblies are foundational resources across the biological sciences as they begin to expose the fundamental building blocks of each species and the molecular toolkits vital for adaptation and survival. High-quality genomes enable insights into evolution, facilitate ecosystem monitoring and protection and conservation of species, access to new biomaterials and biomedicine, advances in agri- and aquaculture, and support planetary health. The amount of information gathered from a species' genome assembly is directly dependent on its quality. However, different sequencing technologies and software solutions generate a wide range of quality outcomes. Here, the Earth BioGenome Project's Sequencing and Assembly committee, together with a large community of researchers performing eukaryote sequencing and assembly, outlines quality standards for a "reference" assembly and formulates recommendations to ensure these standards are met.
ER  -