Skip to content
DraconiticResearch
Search Sources API
197,688 studies31 sourcesUpdated 31 min ago
Peer-reviewedLicence not statedActa Pharmacologica Sinica

Evolution of KRAS molecular glues: from allele-selective to Pan-RAS and protein–protein interaction modulators

  1. 1State Key Laboratory of Innovative Immunotherapy, Shanghai Frontiers Science Center for Drug Target Identification and Delivery, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, 200240 China
  2. 2School·of·Pharmaceutical·Engineering, ·Shenyang·Pharmaceutical·University, Shenyang, 110016 China
  3. 3Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai, 200241 China

Related

  1. PepSpace: An Automated, Physics-Driven Directed Evolution Platform for the De Novo Design of Specific Peptide Binders and Condensate Modulators
    J. Oller Iscar, A. R. Tejedor, A. Feito +4
    bioRxivPreprintCC BY-NC-NDFull textBiophysicsbioRxiv
  2. Conserved and divergent modes of substrate interaction define selective localizations and functions of a Cdc14 phosphatase
    Jun-Song Chen, Alaina H. Willet, Lesley A. Turner +1
    Molecular Biology of the CellPeer-reviewedCC BY 4.0Full textMolecular biology & gene regulationPMC
  3. Direct monitoring of unfolded nascent polypeptides by the CCR4-NOT complex contributes to protein quality control through selective mRNA deadenylation and decay
    G. CAULIER, F. MAUXION, B. SERAPHIN
    bioRxivPreprintAll rights reservedFull textMolecular biology & gene regulationbioRxiv
  4. Protein Folding Interference Enables Selective Cyclin D1 Degradation
    A. Galbiati, E. Colasurdo, A. Patsilinakos +22
    bioRxivPreprintAll rights reservedFull textMolecular biology & gene regulationbioRxiv
  5. BioGraphBench-PPI enables audit-first evaluation of negative-sampling contracts and structural baselines in protein interaction networks
    Alejandro Cabrera-Andrade, Jorge Robalino-Díaz, Iván Dueñas-Espín +2
    Frontiers in bioinformaticsPeer-reviewedCC BYFull textMolecular biology & gene regulationEurope PMC
BibTeX
@article{xiao2026evolution,
  title = {{Evolution of KRAS molecular glues: from allele-selective to Pan-RAS and protein–protein interaction modulators}},
  author = {Xuan-zheng Xiao and Yun-jie Wang and Xiu-feng Pang and Ao Zhang},
  journal = {Acta Pharmacologica Sinica},
  year = {2026},
  month = jul,
  doi = {10.1038/s41401-026-01866-x},
  url = {https://doi.org/10.1038/s41401-026-01866-x},
}
RIS
TY  - JOUR
TI  - Evolution of KRAS molecular glues: from allele-selective to Pan-RAS and protein–protein interaction modulators
AU  - Xuan-zheng Xiao
AU  - Yun-jie Wang
AU  - Xiu-feng Pang
AU  - Ao Zhang
PY  - 2026
DA  - 2026/07/15
JO  - Acta Pharmacologica Sinica
DO  - 10.1038/s41401-026-01866-x
UR  - https://doi.org/10.1038/s41401-026-01866-x
SN  - 1671-4083
SN  - 1745-7254
ER  -