Evaluating the Sealing Potential of Different Materials for Perforation Repair: An In Vitro Study
4 affiliations
- 1Department of Conservative Dentistry and Endodontics, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, IND
- 2Department of Orthodontics and Dentofacial Orthopaedics, Maharaja Ganga Singh Dental College and Research Centre, Sri Ganganagar, IND
- 3Department of Paediatric and Preventive Dentistry, Genesis Institute of Dental Sciences and Research, Firozpur, IND
- 4Department of Paediatric and Preventive Dentistry, Private Practitioner, Delhi, IND
Abstract
Introduction: Root perforations pose a significant challenge in endodontic treatment, necessitating effective sealing materials to prevent microleakage and ensure long-term success. Advances in biocompatible materials have led to the introduction of various repair options, including injectable bioceramics and conventional powder-liquid systems. This study compared the performance of injectable materials (Bio-C Repair, Angelus, Londrina, Paraná, Brazil; and Guttaflow Bioseal, Coltène/Whaledent, Langenau, Germany) with the conventional powder-liquid system (Biodentine, Septodont S.A.S., Saint-Maur-des-Fossés, France) in minimizing microleakage in strip perforation repairs. The null hypothesis stated that there would be no significant difference in microleakage among the tested materials.
Methods: An in vitro study was conducted using 50 extracted human molars. Root canals were prepared using rotary files, and strip perforations were created in the mesiobuccal canal using Gates-Glidden drills. The teeth were divided into five groups of 10 samples each, including three experimental groups (Biodentine, Bio-C Repair, and Guttaflow Bioseal) and two control groups. We assessed microleakage using the dye extraction method and Ultraviolet-Visible spectrophotometry at 550 nm. Statistical analysis was performed using analysis of variance and the Tukey post hoc test, with p < 0.05 considered significant.
Results: Statistically significant differences in microleakage were observed among the groups. Among the experimental groups, Bio-C Repair exhibited the least microleakage, followed by Guttaflow Bioseal and Biodentine.
Conclusion: The findings indicate that injectable root repair materials, such as Bio-C Repair and Guttaflow Bioseal, outperform the conventional powder-and-liquid system of Biodentine in minimizing microleakage. These materials present potential advantages for clinical applications requiring effective root repair.
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BibTeX
@article{kanupriya2026evaluating,
title = {{Evaluating the Sealing Potential of Different Materials for Perforation Repair: An In Vitro Study}},
author = {Kanupriya Kanupriya and Amit Choudhary and Shantun Malhotra and Kanwalpreet K Bhullar and Navchandan Kaur and Monica Monica},
journal = {Cureus},
year = {2026},
month = oct,
doi = {10.7759/cureus.117378},
url = {https://europepmc.org/article/PMC/PMC13725315},
note = {CC BY},
}
RIS
TY - JOUR
TI - Evaluating the Sealing Potential of Different Materials for Perforation Repair: An In Vitro Study
AU - Kanupriya Kanupriya
AU - Amit Choudhary
AU - Shantun Malhotra
AU - Kanwalpreet K Bhullar
AU - Navchandan Kaur
AU - Monica Monica
PY - 2026
DA - 2026/10/03
JO - Cureus
DO - 10.7759/cureus.117378
UR - https://europepmc.org/article/PMC/PMC13725315
AB - Introduction: Root perforations pose a significant challenge in endodontic treatment, necessitating effective sealing materials to prevent microleakage and ensure long-term success. Advances in biocompatible materials have led to the introduction of various repair options, including injectable bioceramics and conventional powder-liquid systems. This study compared the performance of injectable materials (Bio-C Repair, Angelus, Londrina, Paraná, Brazil; and Guttaflow Bioseal, Coltène/Whaledent, Langenau, Germany) with the conventional powder-liquid system (Biodentine, Septodont S.A.S., Saint-Maur-des-Fossés, France) in minimizing microleakage in strip perforation repairs. The null hypothesis stated that there would be no significant difference in microleakage among the tested materials. Methods: An in vitro study was conducted using 50 extracted human molars. Root canals were prepared using rotary files, and strip perforations were created in the mesiobuccal canal using Gates-Glidden drills. The teeth were divided into five groups of 10 samples each, including three experimental groups (Biodentine, Bio-C Repair, and Guttaflow Bioseal) and two control groups. We assessed microleakage using the dye extraction method and Ultraviolet-Visible spectrophotometry at 550 nm. Statistical analysis was performed using analysis of variance and the Tukey post hoc test, with p < 0.05 considered significant. Results: Statistically significant differences in microleakage were observed among the groups. Among the experimental groups, Bio-C Repair exhibited the least microleakage, followed by Guttaflow Bioseal and Biodentine. Conclusion: The findings indicate that injectable root repair materials, such as Bio-C Repair and Guttaflow Bioseal, outperform the conventional powder-and-liquid system of Biodentine in minimizing microleakage. These materials present potential advantages for clinical applications requiring effective root repair.
SN - 2168-8184
ER -