Skip to content
DraconiticResearch
Search Sources API
203,203 studies31 sourcesUpdated 54 min ago
PreprintAll rights reservedbioRxiv

High-throughput platforms for genetic perturbation screening using CRISPR/Cas9 in human iPSC-derived macrophages for drug discovery

  • M. Martufi
  • E. Karagianni
  • T. Papanikos
  • T. Ashlin
  • A. Geladaki
  • B. Carbone
  • K. Remlinger
  • A. Quintero Moreno
  • W. Pembroke
  • C. Haslam
  • N. Zinn
  • D. F. Vlachou
12 more authors
  • M. Almeida
  • D. Tsaousis
  • S. Gade
  • B. Sun
  • M. Maqbool
  • H. Franken
  • F. Ziebell
  • A. Di Tullio
  • L. Entwistle
  • N. Srinivasan
  • M. Lobera
  • L. Mohamet1
  1. 1GSK
Read full textPDFDOICite

Related

  1. 777 High-throughput discovery of rare, functionally potent antigen-reactive TCRs via polyclonal library screening
    Srishti Gupta, Miao Li, Pooja Vaikari +3
    Journal for ImmunoTherapy of CancerPeer-reviewedCC BYFull textImmunologyDOAJ
  2. An AI-Enabled Translational Drug Discovery Framework for NALCN Channelopathy: From High-Throughput Screening to Therapeutic Candidate
    Nattaya Thongsepee, Jeremy A Tanner, Srikanth Polusani +8
    HALPreprintCC BY-NC-ND 4.0Full textNeurosciencePharmacology & toxicologyHALbioRxiv
  3. Closing the phenotyping gap: non-invasive electromagnetic induction enables high-throughput screening of crop root function in the field
    C. Qian, D. Rodriguez, F. A. Monteiro Santos +4
    bioRxivPreprintAll rights reservedFull textPlant biologybioRxiv
  4. An L-threonine-inducible biosensor derived from the tryptophan-repressed trp promoter of Escherichia coli for high-throughput screening of L-threonine overproducers
    B. Su, P. Lai, X. Xiong +4
    bioRxivPreprintAll rights reservedFull text1 citedSystems & synthetic biologybioRxiv
  5. Image-based transposon screening reveals a flavin reductase that restrains intracellular Salmonella replication in macrophages
    C. Ciolli Mattioli, D. Schraivogel, N. Bossel Ben-Moshe +6
    bioRxivPreprintAll rights reservedFull textMicrobiologybioRxiv

Cite

BibTeXRIS
BibTeX
@misc{martufi2026highthroughput,
  title = {{High-throughput platforms for genetic perturbation screening using CRISPR/Cas9 in human iPSC-derived macrophages for drug discovery}},
  author = {M. Martufi and E. Karagianni and T. Papanikos and T. Ashlin and A. Geladaki and B. Carbone and K. Remlinger and A. Quintero Moreno and W. Pembroke and C. Haslam and N. Zinn and D. F. Vlachou and M. Almeida and D. Tsaousis and S. Gade and B. Sun and M. Maqbool and H. Franken and F. Ziebell and A. Di Tullio and L. Entwistle and N. Srinivasan and M. Lobera and L. Mohamet},
  howpublished = {bioRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.11.750978},
  url = {https://www.biorxiv.org/content/10.64898/2026.09.11.750978v1},
}
RIS
TY  - UNPB
TI  - High-throughput platforms for genetic perturbation screening using CRISPR/Cas9 in human iPSC-derived macrophages for drug discovery
AU  - M. Martufi
AU  - E. Karagianni
AU  - T. Papanikos
AU  - T. Ashlin
AU  - A. Geladaki
AU  - B. Carbone
AU  - K. Remlinger
AU  - A. Quintero Moreno
AU  - W. Pembroke
AU  - C. Haslam
AU  - N. Zinn
AU  - D. F. Vlachou
AU  - M. Almeida
AU  - D. Tsaousis
AU  - S. Gade
AU  - B. Sun
AU  - M. Maqbool
AU  - H. Franken
AU  - F. Ziebell
AU  - A. Di Tullio
AU  - L. Entwistle
AU  - N. Srinivasan
AU  - M. Lobera
AU  - L. Mohamet
PY  - 2026
DA  - 2026/09/11
PB  - bioRxiv
DO  - 10.64898/2026.09.11.750978
UR  - https://www.biorxiv.org/content/10.64898/2026.09.11.750978v1
ER  -