Short-term clinical outcomes of 6-Fr versus 8-Fr catheters for percutaneous transhepatic gallbladder drainage in acute calculous cholecystitis: a propensity score-matched analysis
- 1Department of Medicine, Division of Gastroenterology, Showa Medical University Fujigaoka Hospital, Yokohama, 227-8501 Japan
Abstract
Background: Percutaneous transhepatic gallbladder drainage (PTGBD) is a standard drainage option for patients with acute cholecystitis at high surgical risk. The association of between catheter diameter and clinical outcomes remains unclear. We compared short-term clinical outcomes between 6-Fr and 8-Fr catheters used for PTGBD.
Methods: This single-center retrospective observational study included patients who underwent PTGBD for acute calculous cholecystitis. Baseline characteristics between the 6-Fr and 8-Fr groups were adjusted using propensity score matching (PSM). Outcomes were assessed for adverse events (AEs), technical success, clinical success, and 30-day mortality.
Results: A total of 127 and 149 patients were included in the 6-Fr and 8-Fr groups, respectively. After PSM, 71 matched pairs were analyzed. After matching, the AE rate was significantly higher in the 6-Fr group than in the 8-Fr group (28.2% vs. 9.9%; risk difference [RD] 0.18; relative risk 2.85; p = 0.009). Clinical success was significantly higher in the 8-Fr group at days 5 and 7 (91.5% vs. 100%; RD = − 0.08; p = 0.041) but was similar between the groups by day 14 (98.6% vs. 100%; p > 0.999). No significant between-group differences were observed in technical success or 30-day mortality.
Conclusions: Compared with 6-Fr catheters, 8-Fr catheters were associated with fewer short-term AEs and may be associated with earlier clinical improvement. An 8-Fr catheter may be a reasonable option for short-term PTGBD management.
Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s12876-026-05210-9.
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BibTeX
@article{azami2026shortterm,
title = {{Short-term clinical outcomes of 6-Fr versus 8-Fr catheters for percutaneous transhepatic gallbladder drainage in acute calculous cholecystitis: a propensity score-matched analysis}},
author = {Tetsushi Azami and Yuichi Takano and Naoki Tamai and Jun Noda and Fumitaka Niiya and Masatsugu Nagahama},
journal = {BMC Gastroenterology},
year = {2026},
month = aug,
doi = {10.1186/s12876-026-05210-9},
url = {https://doi.org/10.1186/s12876-026-05210-9},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Short-term clinical outcomes of 6-Fr versus 8-Fr catheters for percutaneous transhepatic gallbladder drainage in acute calculous cholecystitis: a propensity score-matched analysis
AU - Tetsushi Azami
AU - Yuichi Takano
AU - Naoki Tamai
AU - Jun Noda
AU - Fumitaka Niiya
AU - Masatsugu Nagahama
PY - 2026
DA - 2026/08/06
JO - BMC Gastroenterology
DO - 10.1186/s12876-026-05210-9
UR - https://doi.org/10.1186/s12876-026-05210-9
AB - Background: Percutaneous transhepatic gallbladder drainage (PTGBD) is a standard drainage option for patients with acute cholecystitis at high surgical risk. The association of between catheter diameter and clinical outcomes remains unclear. We compared short-term clinical outcomes between 6-Fr and 8-Fr catheters used for PTGBD. Methods: This single-center retrospective observational study included patients who underwent PTGBD for acute calculous cholecystitis. Baseline characteristics between the 6-Fr and 8-Fr groups were adjusted using propensity score matching (PSM). Outcomes were assessed for adverse events (AEs), technical success, clinical success, and 30-day mortality. Results: A total of 127 and 149 patients were included in the 6-Fr and 8-Fr groups, respectively. After PSM, 71 matched pairs were analyzed. After matching, the AE rate was significantly higher in the 6-Fr group than in the 8-Fr group (28.2% vs. 9.9%; risk difference [RD] 0.18; relative risk 2.85; p = 0.009). Clinical success was significantly higher in the 8-Fr group at days 5 and 7 (91.5% vs. 100%; RD = − 0.08; p = 0.041) but was similar between the groups by day 14 (98.6% vs. 100%; p > 0.999). No significant between-group differences were observed in technical success or 30-day mortality. Conclusions: Compared with 6-Fr catheters, 8-Fr catheters were associated with fewer short-term AEs and may be associated with earlier clinical improvement. An 8-Fr catheter may be a reasonable option for short-term PTGBD management. Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s12876-026-05210-9.
SN - 1471-230X
ER -