Skip to content
DraconiticResearch
Search Sources API
182,549 studies31 sourcesUpdated 17 min ago
PreprintCC BY-NC-NDbioRxiv

A 28-color panel for classical and non-classical T lymphocytes in decidua and PBMC in rhesus macaques

  • M. J. Mostrom
  • A. Kaur
  • M. D. Fahlberg1
  1. 1Tulane National Biomedical Research Center
Read full textPDFDOICite

Abstract

This 28-color panel was developed to identify classical and non-classical T lymphocytes in decidual leukocytes and peripheral blood mononuclear cells (PBMC) of pregnant rhesus macaques. By profiling these T lymphocytes, we can investigate how maternal immunity balances tolerance to fetal antigens with protection against vertically transmitted pathogens. The selected markers define memory populations and characterize tissue residency, activation, proliferation, cytotoxicity, trafficking, and exhaustion status. This panel also delineates B lymphocytes and NK cells to confirm expected frequencies. The utility of this panel is aimed at evaluating cellular immune correlates of protection against congenital infections at the maternal-fetal interface and PBMC in rhesus macaques.

Related

  1. Movements for Grooming in Rhesus Macaques Co-opted from Feeding Movements
    I. Q. Whishaw, K. Buks, A. Ruiz +2
    bioRxivPreprintAll rights reservedFull textZoology & animal behaviourbioRxiv
  2. A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques
    S. Lee, M. T. Nguyen, M. G. Currier +11
    Nature CommunicationsPeer-reviewedCC BYFull text77 citedMicrobiologyHAL
  3. B-Cell Follicles in the Secondary Lymphatic Tissues Act as a Critical Microanatomical Niche for Sustained Viral Replication, Virus-Host Interaction and Damage During Chronic SIV Infection of Rhesus Macaques.
    Yilun Cheng, Miaoyun Zhao, Jackson Chen +3
    Journal of medical virologyPeer-reviewedCC BYFull textMicrobiologyEurope PMCPMC
  4. Risk management strategies in social grooming among Tonkean and rhesus macaques
    M. Legrand, S. Silvere, N. Bande +6
    bioRxivPreprintCC BY-NC-NDFull textZoology & animal behaviourbioRxiv
  5. Quantitative evaluation of enrichment protocols on rhesus macaques welfare in laboratory environment
    Valentine Morel-Latour, Océane Monnier, Elya Ray +8
    HALPreprintCC BY-NCGeneral biologyHAL

Cite

BibTeXRIS
BibTeX
@misc{mostrom202628color,
  title = {{A 28-color panel for classical and non-classical T lymphocytes in decidua and PBMC in rhesus macaques}},
  author = {M. J. Mostrom and A. Kaur and M. D. Fahlberg},
  howpublished = {bioRxiv},
  year = {2026},
  month = aug,
  doi = {10.64898/2026.08.27.747578},
  url = {https://www.biorxiv.org/content/10.64898/2026.08.27.747578v1},
  note = {CC BY-NC-ND},
}
RIS
TY  - UNPB
TI  - A 28-color panel for classical and non-classical T lymphocytes in decidua and PBMC in rhesus macaques
AU  - M. J. Mostrom
AU  - A. Kaur
AU  - M. D. Fahlberg
PY  - 2026
DA  - 2026/08/27
PB  - bioRxiv
DO  - 10.64898/2026.08.27.747578
UR  - https://www.biorxiv.org/content/10.64898/2026.08.27.747578v1
AB  - This 28-color panel was developed to identify classical and non-classical T lymphocytes in decidual leukocytes and peripheral blood mononuclear cells (PBMC) of pregnant rhesus macaques. By profiling these T lymphocytes, we can investigate how maternal immunity balances tolerance to fetal antigens with protection against vertically transmitted pathogens. The selected markers define memory populations and characterize tissue residency, activation, proliferation, cytotoxicity, trafficking, and exhaustion status. This panel also delineates B lymphocytes and NK cells to confirm expected frequencies. The utility of this panel is aimed at evaluating cellular immune correlates of protection against congenital infections at the maternal-fetal interface and PBMC in rhesus macaques.
ER  -