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Peer-reviewedCC BY-NC-ND 4.0Nature Communications

Sub-stoichiometric degradation is dispensable for potent PROTACs as demonstrated by irreversible covalent BTK degraders

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BibTeX
@article{cheng2026substoichiometric,
  title = {{Sub-stoichiometric degradation is dispensable for potent PROTACs as demonstrated by irreversible covalent BTK degraders}},
  author = {Ran Cheng and Hanfeng Lin and Xin Yu and Shrilekha Misra and Andrew D. Mitchell and Jennifer A. Woyach and Xiaoli Qi and Jin Wang},
  journal = {Nature Communications},
  year = {2026},
  month = oct,
  doi = {10.1038/s41467-026-78239-9},
  url = {https://www.nature.com/articles/s41467-026-78239-9},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Sub-stoichiometric degradation is dispensable for potent PROTACs as demonstrated by irreversible covalent BTK degraders
AU  - Ran Cheng
AU  - Hanfeng Lin
AU  - Xin Yu
AU  - Shrilekha Misra
AU  - Andrew D. Mitchell
AU  - Jennifer A. Woyach
AU  - Xiaoli Qi
AU  - Jin Wang
PY  - 2026
DA  - 2026/10/07
JO  - Nature Communications
DO  - 10.1038/s41467-026-78239-9
UR  - https://www.nature.com/articles/s41467-026-78239-9
SN  - 2041-1723
ER  -