Peer-reviewedCC BYChemical Reviews
Methods to Study the Molecular Mechanism and Drive the Design of Protein Degraders
- 1Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James Lindsay Place, Dundee DD1 5JJ, U.K
Abstract
assays and provide a concise framework for prioritizing and mapping them to decision stages. We also discuss the main factors affecting degrader's cellular performance and principles that have emerged to guide drug design.
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BibTeX
@article{crowe2026methods,
title = {{Methods to Study the Molecular Mechanism and Drive the Design of Protein Degraders}},
author = {Charlotte Crowe and Alessio Ciulli},
journal = {Chemical Reviews},
year = {2026},
month = may,
doi = {10.1021/acs.chemrev.5c00800},
url = {https://doi.org/10.1021/acs.chemrev.5c00800},
note = {CC BY},
}
RIS
TY - JOUR
TI - Methods to Study the Molecular Mechanism and Drive the Design of Protein Degraders
AU - Charlotte Crowe
AU - Alessio Ciulli
PY - 2026
DA - 2026/05/14
JO - Chemical Reviews
DO - 10.1021/acs.chemrev.5c00800
UR - https://doi.org/10.1021/acs.chemrev.5c00800
AB - assays and provide a concise framework for prioritizing and mapping them to decision stages. We also discuss the main factors affecting degrader's cellular performance and principles that have emerged to guide drug design.
SN - 0009-2665
SN - 1520-6890
ER -