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Peer-reviewedCC BYVaccines

HPV Vaccination Uptake Among Vaccine-Eligible U.S. Adults with and Without a Cancer History: A National Health and Nutrition Examination Survey Analysis, 2011-2023.

  1. 1College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL 32307, USA.

Abstract

Background

Human papillomavirus includes more than 200 types, classified by cancer risk. Since 2006, the vaccine has effectively prevented human papillomavirus infection and associated cancers; however, coverage among adults remains low. Furthermore, research examining human papillomavirus vaccination among adults with a cancer history is limited.Objective

To estimate vaccination uptake for human papillomavirus among U.S. adults aged 20-47 and compare uptake by cancer history.Methods

This study used data from the National Health and Nutrition Examination Survey from 2011 to 2023. The final analytic sample included 13,511 adults aged 20-47 with self-reported vaccination status and cancer history. The data were weighted to account for the complex survey design and produce nationally representative estimates.Results

Among eligible adults, 84.7% were unvaccinated, 2.9% were under-vaccinated, and 12.4% had completed the vaccine series. Among eligible adults with a self-reported cancer history, the majority were unvaccinated. Vaccination completion differed by sociodemographic and healthcare-related factors.Conclusions

Human papillomavirus vaccination remained low among eligible U.S. adults, including those with a self-reported cancer history. These findings support efforts to improve adult vaccination coverage and prevent human papillomavirus infections and associated cancers.

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BibTeX
@article{saintibert2026vaccination,
  title = {{HPV Vaccination Uptake Among Vaccine-Eligible U.S. Adults with and Without a Cancer History: A National Health and Nutrition Examination Survey Analysis, 2011-2023.}},
  author = {Jessica Saintibert and Tammie M Johnson},
  journal = {Vaccines},
  year = {2026},
  month = oct,
  doi = {10.3390/vaccines14100892},
  url = {https://europepmc.org/article/MED/42931421},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - HPV Vaccination Uptake Among Vaccine-Eligible U.S. Adults with and Without a Cancer History: A National Health and Nutrition Examination Survey Analysis, 2011-2023.
AU  - Jessica Saintibert
AU  - Tammie M Johnson
PY  - 2026
DA  - 2026/10/12
JO  - Vaccines
DO  - 10.3390/vaccines14100892
UR  - https://europepmc.org/article/MED/42931421
AB  - Background  Human papillomavirus includes more than 200 types, classified by cancer risk. Since 2006, the vaccine has effectively prevented human papillomavirus infection and associated cancers; however, coverage among adults remains low. Furthermore, research examining human papillomavirus vaccination among adults with a cancer history is limited.Objective  To estimate vaccination uptake for human papillomavirus among U.S. adults aged 20-47 and compare uptake by cancer history.Methods  This study used data from the National Health and Nutrition Examination Survey from 2011 to 2023. The final analytic sample included 13,511 adults aged 20-47 with self-reported vaccination status and cancer history. The data were weighted to account for the complex survey design and produce nationally representative estimates.Results  Among eligible adults, 84.7% were unvaccinated, 2.9% were under-vaccinated, and 12.4% had completed the vaccine series. Among eligible adults with a self-reported cancer history, the majority were unvaccinated. Vaccination completion differed by sociodemographic and healthcare-related factors.Conclusions  Human papillomavirus vaccination remained low among eligible U.S. adults, including those with a self-reported cancer history. These findings support efforts to improve adult vaccination coverage and prevent human papillomavirus infections and associated cancers.
SN  - 2076-393X
ER  -